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Lactose Monohydrate 500gm

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Lactose monohydrate is a crystalline form of lactose, a disaccharide sugar composed of glucose and galactose. In its monohydrate form, each lactose molecule is associated with one water molecule, resulting in a hydrated crystalline structure. This white to off-white, odorless powder is widely used in various industries for its functional properties. As a key component of milk and dairy products, lactose monohydrate serves important roles in pharmaceuticals, food manufacturing, and biotechnology. It is commonly employed as a filler or binder in pharmaceutical tablets and capsules, as well as a sweetening agent and texture enhancer in the food industry. The monohydrate form of lactose provides versatility in applications, contributing to its widespread use in different sectors.

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Lactose Monohydrate

Lactose monohydrate has several laboratory uses, primarily in pharmaceutical and analytical applications. Here are some key uses:

  1. Excipient in Drug Formulation:
    • Filler/Diluent: Used as a filler in the preparation of tablets and capsules due to its excellent compressibility.
    • Binder: Acts as a binder in tablet formulations, aiding in the formation of a cohesive mass.
    • Carrier for Dry Powder Inhalers (DPIs): Serves as a carrier substance in dry powder inhalation formulations to aid in the delivery of the active pharmaceutical ingredient.
  2. Reagent in Analytical Chemistry:
    • Chromatography: Used as a standard in chromatography for the analysis of carbohydrates.
    • Calibration: Employed in the calibration of instruments and validation of analytical methods.
  3. Microbiological Media:
    • Culture Media: Incorporated into microbiological culture media to provide a carbohydrate source for the growth of microorganisms, particularly for lactose-fermenting bacteria.
  4. Quality Control and Stability Testing:
    • Reference Standard: Used as a reference standard in quality control laboratories for the development and validation of analytical methods.
    • Stability Studies: Involved in stability studies to assess the shelf life and stability of pharmaceutical products.
  5. Pharmaceutical Research:
    • Formulation Development: Utilized in the research and development of new drug formulations to study the effect of various excipients on the stability and bioavailability of active ingredients.
    • Solubility Studies: Employed in solubility studies to determine the solubility profile of different compounds.
  6. Chemical Synthesis:
    • Precursor: Can be used as a precursor in the synthesis of more complex carbohydrate derivatives.
SKU: ACS47844CHEM0 Category:

When handling lactose monohydrate in a laboratory setting, it’s important to follow standard safety precautions to ensure safe usage and avoid potential hazards. Here are key safety precautions:

Personal Protective Equipment (PPE):

  1. Eye Protection: Wear safety goggles or a face shield to prevent any accidental contact with the eyes.
  2. Skin Protection: Use appropriate protective gloves and a lab coat to minimize skin contact.
  3. Respiratory Protection: If there is a risk of inhaling dust, use a dust mask or respirator.

Handling and Storage:

  1. Ventilation: Work in a well-ventilated area to avoid the accumulation of dust.
  2. Avoid Inhalation: Minimize dust generation and accumulation. Avoid breathing in dust.
  3. Hygiene: Wash hands thoroughly after handling the substance and before eating, drinking, or smoking.
  4. Storage: Store in a cool, dry place, away from direct sunlight and moisture. Ensure containers are tightly closed when not in use.

Spill and Accident Procedures:

  1. Spills: In case of a spill, avoid raising dust. Clean up by sweeping or vacuuming and place the material in a suitable waste container. Use water to clean the spill area if necessary.
  2. First Aid Measures:
    • Inhalation: Move to fresh air. If breathing is difficult, seek medical attention.
    • Skin Contact: Wash with soap and water. Remove contaminated clothing.
    • Eye Contact: Rinse immediately with plenty of water for at least 15 minutes. Seek medical attention if irritation persists.
    • Ingestion: Rinse mouth with water. Seek medical advice if feeling unwell.

Waste Disposal:

  1. Disposal: Dispose of lactose monohydrate waste according to local regulations. Do not release it into the environment.
  2. Containment: Use appropriate containers for disposal to avoid environmental contamination.

Fire Safety:

  1. Fire Hazards: Lactose monohydrate is not highly flammable but can burn if exposed to a strong ignition source.
  2. Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide to extinguish fires.
  3. Firefighting Measures: Wear appropriate protective equipment and self-contained breathing apparatus (SCBA) when fighting fires involving lactose monohydrate.

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