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Polysorbates
Polysorbates are a class of nonionic surfactants derived from sorbitol and fatty acids, commonly used as emulsifiers, solubilizers, and dispersing agents in a wide range of industries. They improve the mixing of oil and water phases, stabilize emulsions, and enhance the texture and consistency of formulations. Polysorbates are widely used in pharmaceuticals, cosmetics, food products, and industrial applications due to their biocompatibility, low toxicity, and effectiveness at low concentrations.
Polysorbates
Primary Uses
- Pharmaceutical Industry
- Used as emulsifiers and solubilizing agents in oral, topical, and injectable drug formulations.
- Helps to stabilize suspensions and emulsions.
- Improves bioavailability of poorly soluble drugs.
- Food Industry
- Acts as emulsifiers in baked goods, ice creams, salad dressings, and beverages.
- Enhances texture, shelf life, and consistency of food products.
- Used in fat-based spreads and confectionery to improve mixing and prevent separation.
- Cosmetics and Personal Care
- Emulsifies oils and water in creams, lotions, shampoos, and conditioners.
- Enhances product texture, stability, and skin feel.
- Helps disperse fragrances and active ingredients evenly.
- Industrial Applications
- Used in textile processing, detergents, and paints as emulsifiers and dispersants.
- Facilitates the formulation of emulsions and suspensions in various manufacturing processes.
Secondary Uses
- Agriculture
- Used as adjuvants in pesticide formulations to improve spreading and adhesion.
- Biomedical Research
- Employed as stabilizers in vaccine formulations and cell culture media.
- Lubricants and Coatings
- Improves miscibility and stability in lubricant and coating formulations.
- Improves miscibility and stability in lubricant and coating formulations.
1. Basic Identification Attributes
- Chemical Name (IUPAC): Polyoxyethylene sorbitan esters (varies by fatty acid chain)
- Common/Trade Name: Polysorbate 20, Polysorbate 40, Polysorbate 60, Polysorbate 80 (most common types)
- CAS Number: Varies (e.g., Polysorbate 80: 9005-65-6)
- HS Code: 3402.19.00 (Surface-active agents)
- Synonyms: Tween (common trade name), Polyoxyethylene sorbitan fatty acid esters
2. Physical & Chemical Properties
- Physical State: Viscous liquid or semi-solid
- Color: Pale yellow to amber
- Odor: Mild, characteristic odor
- pH: Typically 6.0–8.0 in aqueous solution
- Solubility: Soluble in water and alcohol; forms stable emulsions
- HLB (Hydrophilic-Lipophilic Balance): Range from 8.6 to 16.7 depending on type (higher HLB = more hydrophilic)
- Density: Approx. 1.05 g/cm³
3. Safety & Hazard Attributes
- GHS Classification: Generally not classified as hazardous
- Toxicity: Low toxicity; considered safe for food and cosmetic use within regulatory limits
- Irritation Potential: Mild skin and eye irritant at high concentrations
- Flammability: Non-flammable
4. Storage & Handling Attributes
- Storage Conditions: Store in a cool, dry place away from direct sunlight and heat
- Container Type: Supplied in plastic drums, bottles, or bulk containers
- Shelf Life: Typically 2–3 years if stored properly
- Handling Precautions: Avoid inhalation of aerosols and prolonged skin contact
5. Regulatory & Compliance Attributes
- Complies with:
- FDA regulations for food-grade emulsifiers
- Cosmetic ingredient safety standards (e.g., EU Cosmetic Regulation)
- USP/NF monographs for pharmaceutical grades
- REACH and other international chemical safety regulations
- FDA regulations for food-grade emulsifiers
6. Environmental & Health Impact
- Biodegradability: Readily biodegradable
- Ecotoxicity: Low environmental impact when used as directed
- Bioaccumulation: Not expected to bioaccumulate
- Carcinogenicity/Mutagenicity: Not classified as hazardous
Safety Handling Precautions
- PPE Required: Gloves and safety goggles recommended during handling of concentrated material
- Handling Guidelines: Use in well-ventilated areas; avoid inhalation of mist or aerosols
- Storage Measures: Keep containers tightly closed; avoid contamination
First Aid Measures
- Inhalation: Move to fresh air if irritation occurs
- Skin Contact: Wash with soap and water; seek medical advice if irritation persists
- Eye Contact: Rinse thoroughly with water for at least 15 minutes; seek medical attention if irritation continues
- Ingestion: Rinse mouth; seek medical advice if discomfort or symptoms develop
Firefighting Measures
- Fire Hazards: Not flammable but can burn under fire conditions
- Extinguishing Media: Water spray, foam, dry chemical, or CO₂
- Special Precautions: Use standard protective equipment
- Hazardous Combustion Products: May produce carbon oxides and other toxic fumes during combustion
Related products
Booster Emulsifier
Booster Emulsifier is a specialized surfactant-based additive formulated to enhance the stability, texture, and uniformity of emulsions in food, cosmetic, and pharmaceutical formulations. It acts by reducing surface tension between immiscible liquids such as oil and water, facilitating the formation of stable, homogeneous emulsions. Booster Emulsifier is valued for its ability to improve product appearance, extend shelf life, and enhance sensory properties such as mouthfeel and creaminess. It is typically available as a liquid or powder and compatible with a wide range of ingredients.
Carboxymethyl Cellulose Food Grade
Carboxymethyl Cellulose Food Grade is a water-soluble cellulose derivative produced by the etherification of cellulose with monochloroacetic acid. It appears as a fine, white to off-white powder with excellent thickening, stabilizing, and water retention properties. Designed specifically for food applications, this grade complies with food safety regulations and is widely used as a texture modifier, stabilizer, and emulsifier in a variety of processed foods. It enhances product consistency, extends shelf life, and improves moisture retention without altering taste or odor. Being non-toxic, biodegradable, and non-caloric, it is considered safe for human consumption and is approved as a food additive in many countries.
Centrimonium Chloride Solution
Centrimonium Chloride Solution (also known as Cetyltrimethylammonium Chloride), with the chemical formula C₁₉H₄₂ClN, is a quaternary ammonium compound presented here as a 30% aqueous solution. It is a cationic surfactant widely used as an antistatic agent, conditioner, and emulsifier in personal care and industrial applications. This 25kg packaged solution is highly soluble and stable, providing excellent conditioning and antimicrobial properties in hair care formulations, fabric softeners, and disinfectants.
Emulsifying Wax Anionic
Emulsifying Wax Anionic is a versatile surfactant blend composed primarily of fatty alcohols (such as cetyl or stearyl alcohol) and anionic surfactants like sodium lauryl sulfate. It is designed to stabilize oil-in-water (O/W) emulsions by reducing interfacial tension between water and oil phases. It appears as white to off-white solid flakes or pellets, with a mild fatty odor and is dispersible in water with agitation and mild heat. Known for its excellent emulsification, cleansing, and thickening properties, this emulsifying wax is widely used in cosmetics, pharmaceuticals, household cleaners, and industrial applications.
Galaxy MW 257( Lutensol A07)
Galaxy MW 257( Lutensol A07), also known commercially as Lutensol A07, is a nonionic surfactant belonging to the class of ethoxylated alcohols. It is synthesized by ethoxylation of C7 fatty alcohols, resulting in a hydrophilic-lipophilic balance (HLB) suitable for versatile applications in detergency, emulsification, wetting, and dispersing. This liquid surfactant is valued for its excellent surface-active properties, biodegradability, low toxicity, and compatibility with other formulation ingredients. It is widely used in industrial, household, agricultural, and personal care products to improve formulation stability and performance.
Galsilk 700( polyquartenum 7)
Galsilk 700( polyquartenum 7) is a water-soluble cationic polymer known chemically as Polyquaternium-7. It is widely used as a conditioning agent in personal care and cosmetic formulations, prized for its excellent substantivity to hair and skin, providing softness, smoothness, and antistatic effects. This polymer is typically supplied as a clear to slightly hazy viscous liquid or gel. It is compatible with a broad range of surfactants and ingredients, enhancing the sensory profile of shampoos, conditioners, styling products, and skincare formulations. Galsilk 700 is also valued for its film-forming properties and ability to improve product stability.
Polyglyceryl
Polyglyceryl refers to a family of non-ionic surfactants and emulsifiers made by the polymerization of glycerol units. Depending on the number of glycerol units (e.g., Polyglyceryl-2, -3, -6, -10) and fatty acid esterification (e.g., laurate, oleate, stearate), they offer different emulsifying and solubilizing properties. These compounds are biodegradable, mild, and skin-friendly, making them ideal for use in cosmetics, food, pharmaceuticals, and personal care products. Polyglyceryl esters are often chosen in natural and organic product formulations due to their origin and non-toxic profile.
Triethanolamine (TEA)
Triethanolamine (TEA) is a viscous, colorless to pale yellow liquid with a mild ammonia-like odor. It is a multifunctional organic compound widely used in cosmetics, pharmaceuticals, and industrial applications as a pH adjuster, emulsifier, surfactant, and corrosion inhibitor. Triethanolamine neutralizes fatty acids to form soaps and helps stabilize emulsions, making it essential in personal care formulations and various chemical manufacturing processes. Its versatility and compatibility with other ingredients make it a valuable additive in numerous industries.
