Acetone
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Acetone Extra Pure is a high-purity grade of acetone (≥99.5%) specifically purified to meet stringent quality standards for laboratory and industrial applications. This volatile, colorless solvent is characterized by its rapid evaporation rate, excellent solvency power, and minimal impurity content, making it suitable for sensitive chemical processes and analytical applications
Description
Table of Contents
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Primary Uses
- Industrial & Chemical Solvent
- One of the most widely used polar aprotic solvents in laboratories and industries.
- Effective for dissolving plastics, resins, synthetic fibers, and varnishes.
- Used in paint thinners, nail polish removers, and adhesive cleaners.
- Pharmaceutical & Cosmetic Manufacturing
- Used as a solvent in drug formulations (e.g., antibiotics, steroids).
- Key ingredient in nail polish removers due to its ability to dissolve nitrocellulose.
- Found in skincare products (in controlled amounts for exfoliation).
- Laboratory & Research Applications
- Common cleaning agent for lab glassware due to fast evaporation.
- Used in DNA/RNA extraction and protein precipitation.
- Solvent in HPLC (High-Performance Liquid Chromatography).
- Plastics & Synthetic Materials Production
- Key precursor in manufacturing polycarbonates, epoxy resins, and plexiglass (PMMA).
- Used in producing bisphenol A (BPA), a component of plastics.
- Fuel & Energy Applications
- Added to acetylene cylinders to stabilize the gas for welding.
- Investigated as a biofuel additive for improving combustion efficiency.
Secondary Uses
- Household & Cleaning Products
- Removes superglue, grease, and permanent markers.
- Used in electronics cleaning (circuit boards, contacts).
- Medical & Forensic Uses
- Used in histology labs for tissue dehydration before embedding in paraffin.
- Helps in fingerprint development on porous surfaces.
- Food Industry (Indirect Use)
- Approved as an extraction solvent for spices and hops (though residues must be minimized).
- Textile Industry
- Used in dyeing and degreasing wool.
- 3D Printing & Additive Manufacturing
- Used for smoothing ABS (Acrylonitrile Butadiene Styrene) prints via vapor polishing.
PRODUCT KEY FEATURE
Basic Identification Attributes
- Chemical Name (IUPAC): Propan-2-one
- Common/Trade Names:
- Acetone
- Dimethyl ketone
- 2-Propanone
- β-Ketopropane
- CAS Number: 67-64-1
- HS Code: 2914.11.00
- Molecular Formula: C₃H₆O
- Synonyms:
- Dimethyl formaldehyde
- Pyroacetic spirit
- Ketone propane
2. Physical & Chemical Properties
- Physical State: Colorless liquid
- Color & Odor: Colorless with a characteristic sweetish odor
- Melting Point: -94.9°C (-138.8°F)
- Boiling Point: 56.05°C (132.9°F)
- Density: 0.791 g/cm³ at 20°C
- Solubility:
- Miscible with water, ethanol, ether, chloroform, most oils
- pH Level: Neutral (~7)
- Vapor Pressure: 184 mmHg at 20°C
- Flash Point: -20°C (-4°F) (closed cup)
- Autoignition Temperature: 465°C (869°F)
- Viscosity: 0.32 cP at 20°C
- Refractive Index: 1.359 at 20°C
3. Safety & Hazard Attributes
- Hazard Class (GHS):
- Flammable Liquid (Category 2)
- Eye Irritant (Category 2)
- STOT Single Exposure (Category 3)
- NFPA Ratings:
- Health: 1
- Flammability: 3
- Reactivity: 0
- Exposure Limits:
- OSHA PEL: 1000 ppm (2400 mg/m³)
- ACGIH TLV: 500 ppm (1180 mg/m³)
- NIOSH REL: 250 ppm (590 mg/m³)
- Reactivity:
- Forms explosive peroxides with strong oxidizers
- Reacts violently with chloroform + base
- Incompatible with strong acids, alkalis, oxidizing agents
4. Storage & Handling Attributes
- Storage Conditions:
- Store in cool, well-ventilated area
- Keep away from heat/sparks/open flames
- Temperature <30°C recommended
- Incompatible Materials:
- Strong oxidizers (nitric acid, hydrogen peroxide)
- Chloroform + base mixtures
- Strong acids
- Container Type:
- Steel, aluminum, or HDPE containers
- Ground containers during transfer
- Shelf Life: Indefinite if properly stored
- Special Handling:
- Use explosion-proof equipment
- Chemical goggles and gloves recommended
- Local exhaust ventilation preferred
5. Regulatory & Compliance Attributes
- Regulatory Status:
- EPA: Listed as VOC (40 CFR 51.100)
- REACH: Registered
- FDA: Approved as indirect food additive (21 CFR 175.105)
- Hazard Symbols (GHS):
- Flame
- Exclamation mark
- Transportation Restrictions:
- UN Number: 1090
- Hazard Class: 3 (Flammable Liquid)
- Packing Group: II
- Waste Disposal:
- RCRA: Not listed as hazardous waste
- Incineration preferred method
6. Environmental & Health Impact
- Ecotoxicity:
- LC50 (fish): 4,400-8,800 mg/L (96h)
- EC50 (daphnia): >1,000 mg/L (48h)
- Persistence in Environment:
- Readily biodegradable (aerobic half-life: 1-10 days)
- Atmospheric half-life: ~22 days
- Carcinogenicity/Mutagenicity:
- IARC: Not classifiable (Group 3)
- NTP: Not listed
- ACGIH: Not classified
- Biodegradability:
- 90% in 28 days (OECD 301B)
- BOD5: 0.8-1.2 g O₂/g acetone
SAFETY HANDLING
1. Safety Precautions
Personal Protective Equipment (PPE):
- Gloves: Nitrile or neoprene (latex provides limited protection)
- Eye Protection: Safety goggles or face shield
- Respiratory Protection: Organic vapor respirator in poorly ventilated areas
- Clothing: Lab coat or chemical-resistant apron
Handling & Storage:
- Use in well-ventilated areas (preferably fume hood for large quantities)
- Ground containers to prevent static sparks
- Keep away from heat, sparks, open flames, and oxidizers
- Store in approved flammable liquid containers
- Maintain temperature below 38°C (100°F)
Hygiene Practices:
- No eating, drinking, or smoking in handling areas
- Wash hands thoroughly after use
- Avoid inhalation of vapors
2. First Aid Measures
Inhalation:
- Move to fresh air immediately
- Administer oxygen if breathing is difficult
- Seek medical attention if symptoms persist
Skin Contact:
- Remove contaminated clothing
- Wash with soap and water for 15 minutes
- Apply moisturizer if dryness occurs
Eye Contact:
- Flush with running water for at least 15 minutes
- Hold eyelids open during flushing
- Seek immediate medical attention
Ingestion:
- Rinse mouth with water
- Do NOT induce vomiting
- Seek medical attention immediately
3. Firefighting Measures
Fire Characteristics:
- Extremely flammable (Flash point: -20°C/-4°F)
- Vapors can travel to ignition sources and flash back
- Forms explosive mixtures with air (LEL 2.5%, UEL 12.8%)
Extinguishing Media:
- Dry chemical powder
- CO₂
- Alcohol-resistant foam
- Water spray (to cool containers)
Firefighting Procedures:
- Evacuate area immediately
- Wear self-contained breathing apparatus (SCBA)
- Cool containers with water spray from protected position
- Stop leak if safe to do so
- Do not use water jet (may spread fire)
4. Spill Management
Small Spills:
- Absorb with inert material (vermiculite, sand)
- Place in chemical waste container
- Ventilate area thoroughly
Large Spills:
- Evacuate area
- Eliminate all ignition sources
- Contain spill with non-combustible absorbents
- Prevent entry into drains or watercourses
5. Storage & Disposal
Storage:
- Store in flammable liquids cabinet
- Keep containers tightly closed
- Separate from oxidizers and acids
- Use explosion-proof electrical equipment
Disposal:
- Collect as hazardous waste
- Follow local regulations for disposal
- Never pour down drains
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