Citric Acid Monohydrate Extra Pure
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Citric Acid Monohydrate Extra Pure is a highly refined, crystalline organic acid commonly used in laboratory settings for its chelating, buffering, and acidifying properties. With one molecule of water of crystallization, it serves as a reliable pH adjuster and complexing agent in analytical chemistry, titrations, and biochemical experiments. Its extra pure grade ensures minimal contaminants, making it suitable for sensitive applications in pharmaceutical research, food analysis, and preparation of reagent solutions. Soluble in water and ethanol, it is stable under normal lab conditions but should be stored in a cool, dry place in tightly sealed containers to prevent clumping and moisture absorption.
Citric Acid Monohydrate Extra Pure
Primary Uses
- Buffer Preparation
- Commonly used to prepare citrate buffers for maintaining acidic to neutral pH (3.0–6.2) in biochemical and analytical experiments.
- Chelating Agent
- Binds to metal ions like Ca²⁺, Mg²⁺, and Fe³⁺ in complexometric titrations or metal ion removal experiments.
- Standard for Titration
- Used in acid-base titration to calibrate alkaline solutions or as a primary standard in volumetric analysis.
- pH Adjustment
- Added to experimental media and solutions to adjust and stabilize pH, especially in microbial and enzymatic studies.
Secondary Uses
- Analytical Reagent
- Employed in colorimetric tests or precipitation reactions involving metal ions.
- Carbon Source in Microbiology
- Serves as an organic carbon source in selective culture media for microbial growth.
- Cleaning Agent in Laboratory Equipment
- Helps remove limescale or metal salt deposits from lab glassware or metal instruments without the use of strong acids.
- Precursor for Citrate Salts
- Used in the synthesis of other laboratory-grade chemicals like sodium citrate or ammonium citrate.
1. Basic Identification Attributes
- Chemical Name: Citric Acid Monohydrate
- CAS Number: 5949-29-1
- HS Code: 2918.14.00
- Molecular Formula: C₆H₈O₇·H₂O
- Molecular Weight: 210.14 g/mol
- Synonyms: 2-Hydroxy-1,2,3-propane-tricarboxylic acid monohydrate
2. Physical & Chemical Properties
- Appearance: Colorless to white crystalline powder
- Odor: Odorless
- Taste: Strongly acidic (sour)
- Solubility: Freely soluble in water (59 g/100 mL at 20°C), soluble in ethanol
- Melting Point: ~100°C (decomposes with loss of water)
- Density: ~1.542 g/cm³
- pH (1% solution): ~2.2
3. Safety & Hazard Attributes
- GHS Classification:
- H319: Causes serious eye irritation
- NFPA Ratings:
- Health: 1
- Flammability: 0
- Reactivity: 0
- First Aid Measures:
- Inhalation: Move to fresh air, rinse nose with water
- Skin/Eyes: Rinse thoroughly with water for several minutes
- Ingestion: Rinse mouth and drink water; generally regarded as safe in small quantities
4. Storage & Handling Attributes
- Storage Conditions:
- Store in a cool, dry, well-ventilated area
- Keep container tightly closed and protected from moisture
- Container Type: Polyethylene or HDPE jars, fiber drums with liners
- Stability: Stable under normal storage conditions
- Incompatible Materials: Strong oxidizers, strong bases
- Shelf Life: 2–3 years (if kept dry and sealed)
5. Regulatory & Compliance Attributes
- Hazard Symbols:
- EINECS Number: 201-069-1
- FDA Status: GRAS (Generally Recognized As Safe)
- E Number: E330 (Food additive)
6. Applications in Laboratory & Industry
- Laboratory Use:
- Buffering agent
- Standard acid in titrations
- pH adjustment in biochemical experiments
- Other Industries:
- Food & Beverage: Flavoring agent, preservative
- Cosmetics: pH regulator, antioxidant
- Pharmaceuticals: Effervescent formulations
- Cleaning Products: Lime scale remover, chelating agent
SAFETY PRECAUTIONS
- PPE Required:
- Lab coat
- Safety goggles
- Nitrile gloves
- Dust mask (if powder is airborne)
- Handling:
- Avoid inhaling dust.
- Avoid contact with eyes and prolonged skin exposure.
- Handle in a well-ventilated area or under fume hood if in powder form.
- Wash hands thoroughly after use.
- Storage:
- Store in a tightly sealed container.
- Keep in a cool, dry place away from strong bases or oxidizing agents.
FIRST AID MEASURES
- Inhalation:
- Move to fresh air.
- Seek medical advice if irritation persists.
- Skin Contact:
- Wash with soap and water.
- Remove contaminated clothing.
- Seek medical attention if skin becomes irritated.
- Eye Contact:
- Rinse thoroughly with water for at least 15 minutes.
- Keep eyelids open and move eyes around during flushing.
- Get medical attention if irritation continues.
- Ingestion:
- Rinse mouth with water.
- Drink water to dilute.
- Usually not harmful in small quantities, but seek medical advice if discomfort occurs.
FIREFIGHTING MEASURES
- Flammability:
- Not flammable under normal conditions, but combustible in powder form.
- Suitable Extinguishers:
- Dry chemical
- CO₂
- Water spray
- Foam
- Fire Hazards:
- Combustion may release CO, CO₂, and irritating fumes.
- Fine dust may form explosive mixtures with air.
- Firefighting Gear:
- Wear full protective clothing and self-contained breathing apparatus (SCBA).
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