Santophene (4-chloro-2-benzylphenol)
Santophene (4-chloro-2-benzylphenol) is a chlorinated phenolic compound used primarily as a biocide and preservative in various industrial applications. It exhibits strong antimicrobial properties, effectively controlling the growth of bacteria, fungi, and algae. This compound is widely applied in coatings, paints, wood preservation, and water treatment to protect materials from microbial degradation and extend their service life.
Primary Uses
Industrial Biocide
Used in paints, coatings, and varnishes to prevent microbial growth and spoilage.
Employed as a wood preservative to protect against fungal decay and insect attack.
Incorporated in cooling water systems and paper mills as a biocide to control microbial contamination.
Preservative
Utilized in adhesives and sealants to inhibit microbial degradation.
Applied in leather processing to prevent bacterial and fungal growth.
Secondary Uses
Agriculture
Investigated as a potential pesticide or fungicide due to its antimicrobial properties.
Research
Used in microbiological studies to evaluate antimicrobial efficacy and resistance mechanisms.
Basic Identification Attributes
Chemical Name (IUPAC): 4-chloro-2-benzylphenol
Common/Trade Name: Santophene
CAS Number: 118-92-3
HS Code: 2907.19
Synonyms: Chlorobenzylphenol; 4-chloro-2-(phenylmethyl)phenol
Physical & Chemical Properties
Physical State: Solid (crystalline powder)
Color & Odor: White to pale yellow; phenolic odor
Melting Point: Approx. 80–85 °C
Solubility: Slightly soluble in water; soluble in organic solvents such as ethanol and ether
Safety & Hazard Attributes
GHS Classification: Harmful if swallowed; irritant to skin and eyes
Toxicity: Moderate; handle with care to avoid exposure
Exposure Limits: Follow safety guidelines for phenolic compounds
Storage & Handling Attributes
Storage Conditions: Store in a cool, dry, well-ventilated area away from oxidizing agents and heat sources
Container Type: Sealed, moisture-proof containers
Shelf Life: Stable for 2–3 years under proper storage
Handling Precautions: Use gloves and eye protection; avoid dust generation
Regulatory & Compliance Attributes
Complies with relevant industrial biocide regulations
Subject to chemical safety and environmental regulations in various jurisdictions
Environmental & Health Impact
Biodegradability: Moderately biodegradable
Ecotoxicity: Toxic to aquatic life; avoid environmental release
Bioaccumulation: Potential for moderate bioaccumulation
PPE Required: Gloves, goggles, and protective clothing recommended
Handling Guidelines: Work in well-ventilated areas; avoid inhalation and skin contact
Storage Measures: Keep containers tightly closed and stored in a dry environment
First Aid Measures
Inhalation: Move to fresh air; seek medical attention if respiratory irritation occurs
Skin Contact: Wash immediately with soap and water; seek medical advice if irritation persists
Eye Contact: Rinse thoroughly with water for 15 minutes; obtain medical attention if needed
Ingestion: Do not induce vomiting; seek immediate medical care
Firefighting Measures
Fire Hazards: Combustible solid; emits toxic fumes when heated or burned
Extinguishing Media: Use foam, dry chemical, or CO₂
Special Precautions: Wear full protective gear and self-contained breathing apparatus
Hazardous Combustion Products: Carbon oxides, chlorine-containing compounds

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