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Vitamin B1 Mono Nitrate Extra Pure
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Vitamin B1 Mono Nitrate Extra Pure is a high-purity, white to pale yellow crystalline powder widely used as a vitamin B1 source in pharmaceutical, nutritional, and analytical applications. It is known for its enhanced chemical stability compared to thiamine hydrochloride and is commonly used in sustained-release supplements and fortified foods. This grade meets stringent purity requirements suitable for research, pharmaceutical formulation, and dietary supplementation. The compound is sensitive to moisture and should be stored in dry, cool, and dark conditions. Proper PPE is recommended during handling due to dust potential, though it is generally safe under normal conditions.
Description
Vitamin B1 Mono Nitrate Extra Pure
PRIMARY USES
Analytical Reagent & Laboratory Applications
- Used as a reference standard in vitamin B1 quantification by HPLC and other analytical techniques
- Employed in biochemical research to study thiamine nitrate metabolism and enzymatic functions
- Utilized in quality control of vitamin B1 nitrate pharmaceutical and nutraceutical products
- Applied in cell culture studies focusing on vitamin B1’s metabolic roles
Pharmaceutical & Nutraceutical Industry
- Active ingredient in oral vitamin B1 supplements, particularly sustained-release formulations due to improved stability
- Used for prevention and treatment of thiamine deficiency diseases such as beriberi and neuropathies
- Incorporated in multivitamin and multimineral complexes supporting nervous system and energy metabolism
- Preferred in certain formulations for its enhanced chemical stability compared to thiamine hydrochloride
SECONDARY USES
Food Industry (in regulated quantities)
- Added as a fortificant in cereals, flour, and bakery products to improve dietary vitamin B1 intake
- Included in infant formula and nutritional beverages for enrichment
- Used in animal feed to support growth and metabolic functions
Cosmetic and Personal Care Industry
- Occasionally used in skin care products for its antioxidant and conditioning properties
PRODUCT KEY FEATURES
- Basic Identification Attributes
- Chemical Name: Thiamine Mononitrate (Vitamin B1 Mono Nitrate)
- CAS Number: 1054-81-7
- HS Code: 2936.29.00
- Molecular Formula: C₁₂H₁₇N₄O₃S
- Synonyms: Thiamine Nitrate, Vitamin B1 Nitrate
- Physical & Chemical Properties
- Physical State: Fine crystalline powder
- Color & Odor: White to pale yellow, odorless
- Melting Point: 248–252 °C (decomposes)
- Solubility: Slightly soluble in water (~4.5 g/100 mL at 20 °C), practically insoluble in ethanol
- Stability: More chemically stable than thiamine hydrochloride, especially in dry form
- pH Level: Slightly acidic in aqueous solution
- Safety & Hazard Attributes
- Hazard Class (GHS Classification): Not classified as hazardous under normal handling
- NFPA Ratings: Health 1, Flammability 0, Reactivity 0
- Exposure Limits: No specific OSHA PEL or ACGIH TLV established
- Reactivity: Stable under recommended storage conditions
- Storage & Handling Attributes
- Storage Conditions: Store in a cool, dry, dark, and well-ventilated place
- Incompatible Materials: Strong oxidizers and alkalis
- Container Type: Sealed, airtight containers preferably amber or opaque
- Shelf Life & Expiration Date: Stable for 2–3 years if properly stored
- Special Handling Requirements: Use gloves, avoid dust inhalation, handle in well-ventilated environment
- Regulatory & Compliance Attributes
- Regulatory Status: Approved for pharmaceutical, food, and nutraceutical use by FDA and other authorities
- Transportation Restrictions: Not classified as hazardous for transport
- Environmental & Health Impact
- Ecotoxicity: Low aquatic toxicity
- Persistence in Environment: Biodegradable under aerobic conditions
- Carcinogenicity/Mutagenicity: Not classified as carcinogenic or mutagenic
- Biodegradability: Biodegradable
SAFETY HANDLING PRECAUTIONS
SAFETY PRECAUTIONS
Personal Protective Equipment (PPE):
- Wear chemical-resistant gloves
- Use safety goggles
- Wear protective clothing
- Use dust mask if dust is generated
Handling:
- Handle in a well-ventilated area
- Avoid skin and eye contact
- Avoid inhalation of dust
- Wash hands thoroughly after handling
Storage:
- Store in tightly closed containers
- Keep in cool, dry, and dark conditions
- Avoid exposure to incompatible substances and moisture
FIRST AID MEASURES
Inhalation:
- Move to fresh air immediately
- Seek medical attention if breathing difficulty occurs
Skin Contact:
- Wash with soap and water thoroughly
- Remove contaminated clothing
- Seek medical advice if irritation develops
Eye Contact:
- Rinse immediately with plenty of water for 15 minutes
- Seek medical attention if irritation persists
Ingestion:
- Rinse mouth with water
- Do not induce vomiting unless advised
- Seek medical attention if symptoms occur
FIRE FIGHTING MEASURES
Flammability:
- Combustible but not highly flammable
Extinguishing Media:
- Use dry chemical, CO₂, foam, or water spray
Hazardous Combustion Products:
- May release nitrogen oxides, sulfur oxides, carbon monoxide, and dioxide upon decomposition
Firefighter Protection:
- Wear self-contained breathing apparatus (SCBA) and protective gear
- Avoid inhalation of combustion products
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