Sulphadoxine BP 98 Amaris Chemicals
Chocolate Liquid Flavour Food Grade Amaris Chemicals
Chocolate Liquid Flavour Original price was: $ 34.55.Current price is: $ 34.44.
Back to products
Coconut Water Soluble Fragrance Amaris Chemicals
Coconut Water Soluble Fragrance Original price was: $ 22.20.Current price is: $ 22.11.
PHARMACEUTICAL GRADE USP GRADE

Sulphadoxine

WhatsApp Order

Sulphadoxine BP is a long-acting synthetic sulfonamide antibiotic used primarily in combination therapies for treating malaria and certain bacterial infections. Its prolonged half-life makes it suitable for single-dose treatments and prophylaxis. The British Pharmacopoeia (BP) 98% grade ensures pharmaceutical-grade purity, making it suitable for incorporation into human and veterinary medicinal formulations.

Compare
Add to wishlist
Category: Tags: , , , , ,
Description

Sulphadoxine

Primary Uses 

  1. Human Medicine
  • Antimalarial Agent: Primarily used in combination with pyrimethamine (as Fansidar) for treatment and prophylaxis of malaria, especially Plasmodium falciparum infections.
  • Antibacterial Agent: Occasionally used to treat bacterial infections susceptible to sulfonamides, particularly in tropical regions.
  1. Veterinary Medicine
  • Antimicrobial Agent: Used in combination therapies for prevention and treatment of protozoal and bacterial infections in livestock.

Secondary Uses

  1. Research & Development
  • Pharmaceutical Studies: Used in pharmacokinetic and formulation research for antimalarial and sulfonamide drugs.
  • Drug Resistance Monitoring: Utilized in studies monitoring drug resistance patterns in malaria parasites.
  1. Public Health Programs
  • Mass Drug Administration: Employed in malaria-endemic regions as part of public health interventions.
KEY PRODUCT FEATURES

1. Basic Identification Attributes

  • Chemical Name (IUPAC): 4-Amino-N-(5,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide
  • Common/Trade Name: Sulphadoxine BP 98
  • CAS Number: 2447-57-6
  • HS Code: 2941.20.00
  • Synonyms: Sulfadoxine, Sulphadoxine

2. Physical & Chemical Properties

  • Physical State: White crystalline powder
  • Color & Odor: White; odorless to faint sulfur-like odor
  • Melting Point: 190–194 °C
  • Solubility: Slightly soluble in water; soluble in alkaline solutions and organic solvents
  • Density: Approx. 1.5 g/cm³

3. Safety & Hazard Attributes

  • GHS Classification: May cause allergic skin reactions and serious hypersensitivity reactions
  • Toxicity: Moderate toxicity; risk of severe adverse reactions like Stevens-Johnson syndrome
  • Exposure Limits: No specific occupational limits; handle with care

4. Storage & Handling Attributes

  • Storage Conditions: Store in a cool, dry, well-ventilated area, away from light and moisture
  • Container Type: Sealed HDPE or glass containers
  • Shelf Life: 24 months under recommended storage conditions
  • Handling Precautions: Avoid dust generation; use PPE such as gloves and masks

5. Regulatory & Compliance Attributes

  • Complies with British Pharmacopoeia (BP) standards
  • Manufactured under Good Manufacturing Practices (GMP)
  • Approved for use in antimalarial combination therapies by relevant regulatory authorities

6. Environmental & Health Impact

  • Biodegradability: Limited biodegradability under aerobic conditions
  • Ecotoxicity: Potentially toxic to aquatic organisms; avoid environmental release
  • Bioaccumulation: Not significant
SAFETY HANDLING PRECAUTIONS

Safety Handling Precautions

  • PPE Required: Gloves, protective clothing, and dust masks recommended
  • Handling Guidelines: Use in well-ventilated areas; avoid inhalation and skin contact
  • Storage Measures: Keep containers tightly closed and dry

First Aid Measures

  • Inhalation: Remove to fresh air; seek medical attention if respiratory symptoms develop
  • Skin Contact: Wash thoroughly with soap and water; discontinue use if irritation occurs
  • Eye Contact: Rinse eyes with water for at least 15 minutes; seek medical help if irritation persists
  • Ingestion: Rinse mouth and seek medical advice promptly

Firefighting Measures

  • Fire Hazards: Combustible solid
  • Extinguishing Media: Use water spray, foam, dry chemical, or CO₂ extinguishers
  • Hazardous Combustion Products: Carbon oxides, nitrogen oxides, sulfur oxides

Related products

Dicyclomine HCL Amaris Chemicals
Compare

Dicyclomine Hydrochloride

Dicyclomine Hydrochloride is an anticholinergic and antispasmodic agent used primarily to relieve smooth muscle spasms in the gastrointestinal tract. It works by blocking muscarinic receptors, thereby reducing muscle contractions and spasms, which helps alleviate symptoms of irritable bowel syndrome (IBS) and other functional bowel disorders. It is commonly available in oral tablets, capsules, and injectable formulations.

Add to wishlist
Diphenhydramine HCL BP Amaris Chemicals
Compare

Diphenhydramine HCL BP

Diphenhydramine HCL BP is a first-generation antihistamine with potent anticholinergic, sedative, and antiemetic properties. It is commonly used to relieve symptoms associated with allergies, hay fever, the common cold, and motion sickness. Diphenhydramine HCL is a white crystalline powder, highly soluble in water, making it suitable for oral, topical, and injectable pharmaceutical formulations. Due to its ability to cross the blood-brain barrier, it causes sedation and is often used as a sleep aid and for managing Parkinson’s disease symptoms.

Add to wishlist
Guaiphenesin BP Amaris Chemicals
Compare

Guaiphenesin BP

Guaiphenesin BP is a white crystalline powder or granules with a faint characteristic odor, classified as an expectorant used primarily in pharmaceutical formulations to relieve chest congestion. It works by loosening and thinning mucus in the airways, making it easier to cough up and clear from the respiratory tract. It is widely utilized in cough syrups, tablets, and cold remedies. Recognized for its mucolytic and muscle-relaxant properties, Guaiphenesin is included in both prescription and over-the-counter medications worldwide.

Add to wishlist
Hydrocortisone Acetate Amaris Chemicals
Compare

Hydrocortisone Acetate

Hydrocortisone Acetate is a synthetic corticosteroid ester derived from hydrocortisone (cortisol). It is a white to off-white crystalline powder, practically insoluble in water but soluble in alcohol and acetone. This compound exhibits potent anti-inflammatory, immunosuppressive, and anti-allergic properties, making it widely used in pharmaceutical and dermatological formulations. Hydrocortisone Acetate acts by modulating gene expression to reduce the production of inflammatory mediators, thereby alleviating symptoms in various inflammatory and autoimmune conditions.

Add to wishlist
Ivermectin BP Vet Amaris Chemicals
Compare

Ivermectin BP Vet

Ivermectin BP Vet is a potent, broad-spectrum antiparasitic agent widely used in veterinary medicine. It belongs to the avermectin family and works by disrupting nerve and muscle function in parasites, leading to paralysis and death. Ivermectin is highly effective against a range of internal and external parasites, including gastrointestinal worms, lungworms, mites, lice, and certain ticks. Available in oral, injectable, and topical forms, it is trusted for use in livestock, poultry, and companion animals. Its reliable efficacy, wide safety margin, and ease of administration make it an essential treatment in animal health and parasite control programs.

Add to wishlist
Methyl Salicylate BP Amaris Chemicals
Compare

Methyl Salicylate BP

Methyl Salicylate BP is a clear, colorless to pale yellow oily liquid with a characteristic strong, sweet, and minty odor. It is an organic ester commonly used for its analgesic, anti-inflammatory, and flavoring properties. Methyl Salicylate is widely used in pharmaceutical preparations, topical pain relief products, cosmetics, and as a fragrance ingredient.

Add to wishlist
Metronidazole Benzoate BP Amaris Chemicals
Compare

Metronidazole Benzoate BP

Metronidazole Benzoate BP is a benzoate ester derivative of metronidazole, used primarily as an antiprotozoal and antibacterial agent. It is a prodrug that hydrolyzes in the body to release metronidazole, making it more palatable for pediatric and geriatric oral suspensions. It complies with the British Pharmacopoeia (BP) standards for purity and efficacy.

Add to wishlist
Norfloxacin Amaris Chemicals
Compare

Norfloxacin

Norfloxacin is a synthetic broad-spectrum fluoroquinolone antibiotic used primarily to treat bacterial infections. It works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication, transcription, repair, and recombination, leading to bacterial cell death. Norfloxacin is effective against various Gram-negative and some Gram-positive bacteria and is commonly used in urinary tract infections, prostatitis, and gastroenteritis.

 

Add to wishlist