Lactose Monohydrate Extra Pure
Lactose Monohydrate Extra Pure is a high-purity, crystalline disaccharide composed of glucose and galactose, containing one molecule of water per lactose unit. It is widely used in laboratory settings for biochemical research, nutrient media preparation, and as an excipient in pharmaceutical formulation studies. Its consistent solubility and stability make it ideal for carbohydrate analysis, fermentation experiments, and as a mild reducing sugar in analytical reactions. The extra pure grade ensures low impurity levels, supporting accurate and reproducible results in sensitive scientific applications. Proper storage in a cool, dry environment is essential to maintain its crystalline form and prevent caking.
Lactose Monohydrate Extra Pure
Primary Laboratory Uses:
- Pharmaceutical Excipient:
Widely used as a diluent or filler in tablet and capsule formulations due to its stability, compressibility, and low reactivity. - Microbiological Culture Media Component:
Included as a carbohydrate source in various culture media (e.g., MacConkey agar) to support the growth and differentiation of microorganisms. - Calibration Standard in Analytical Chemistry:
Utilized as a reference compound or standard in HPLC, IR, and NMR for method development and validation, especially in pharmaceutical analysis.
Secondary Laboratory Uses:
- Carrier for Dry Powder Inhalation Studies:
Employed as a carrier substance in dry powder inhaler (DPI) formulations during aerosol and respiratory drug delivery research. - Research on Carbohydrate Metabolism:
Serves as a model for disaccharide sugar in biochemical studies of enzyme activity (e.g., lactase) and lactose intolerance mechanisms. - Lyophilization (Freeze Drying) Support:
Used as a cryoprotectant or bulking agent in the freeze-drying of biologicals and pharmaceuticals.
1. Basic Identification Attributes
- Chemical Name: Lactose Monohydrate
- Synonyms: Milk sugar; β-D-Galactopyranosyl-(1→4)-D-glucose monohydrate
- Chemical Formula: C₁₂H₂₂O₁₁·H₂O
- CAS Number: 64044-51-5
- Molecular Weight: 360.31 g/mol
- Grade: Extra Pure (suitable for analytical and laboratory use)
- Appearance: White crystalline powder
- Odor: Odorless
- Solubility: Soluble in water, practically insoluble in alcohol
- Taste: Mildly sweet
2. Safety & Hazard Attributes
- GHS Classification: Not classified as hazardous
- Hazard Statements: None under normal laboratory handling
- Precautionary Statements:
- Avoid inhalation of dust
- Use in a well-ventilated area
- Avoid contact with eyes
- Personal Protective Equipment (PPE):
- Lab coat
- Safety goggles
- Dust mask or respirator if powder is airborne
- Gloves (nitrile or latex)
- First Aid Measures:
- Inhalation: Move to fresh air; seek attention if symptoms persist
- Skin Contact: Wash with soap and water
- Eye Contact: Rinse with plenty of water for at least 15 minutes
- Ingestion: Rinse mouth; non-toxic but seek medical advice if necessary
- Fire Hazards:
- Not highly flammable, but dust may form explosive mixtures with air
- Extinguishing Media: Use water spray, dry chemical, CO₂, or foam
- Special Notes: Handle powders with caution to prevent airborne dispersion
3. Storage & Handling Attributes
- Storage Conditions:
- Store in a tightly sealed container
- Keep in a cool, dry place
- Protect from moisture and strong oxidizing agents
- Handling Tips:
- Avoid generating dust
- Use clean, dry utensils to avoid contamination
4. Laboratory Applications
- Primary Uses:
- As a carrier or diluent in pharmaceutical formulations
- Standard in biochemical assays and enzyme reactions
- Used in microbiology culture media
- Excipient in tablet and capsule production
- Secondary Uses:
- Used in food analysis and nutritional studies
- Research in carbohydrate metabolism and lactose intolerance
- Calibration and quality control testing in pharmaceutical labs
SAFETY PRECAUTIONS
Personal Protective Equipment (PPE):
- Wear a lab coat, protective goggles, and nitrile gloves.
- Use a dust mask if airborne powder is generated.
- Ensure good ventilation or use under a fume hood.
Handling:
- Avoid creating or inhaling dust.
- Avoid contact with skin, eyes, and clothing.
- Wash hands thoroughly after handling.
- Handle in accordance with good laboratory hygiene practices.
Storage:
- Store in a cool, dry, and well-ventilated place.
- Keep the container tightly closed.
- Protect from moisture and incompatible substances like strong oxidizers.
FIRST AID MEASURES
Inhalation:
- Move the affected person to fresh air.
- If breathing is difficult, seek medical attention.
Skin Contact:
- Wash skin with soap and water.
- Remove contaminated clothing.
- Seek medical attention if irritation develops.
Eye Contact:
- Rinse cautiously with water for several minutes.
- Remove contact lenses if present and easy to do.
- Continue rinsing and get medical advice if irritation persists.
Ingestion:
- Rinse mouth with water.
- Drink water if the person is conscious.
- Seek medical advice if symptoms occur.
FIRE FIGHTING MEASURES
Flammability:
- Not highly flammable but can form explosive dust-air mixtures.
Extinguishing Media:
- Use water spray, dry chemical powder, or CO₂.
- Avoid high-pressure water streams that may disperse dust.
Hazardous Combustion Products:
- May produce carbon monoxide and carbon dioxide when burned.
Firefighter Protection:
- Use self-contained breathing apparatus (SCBA).
- Wear full protective gear.
- Avoid inhalation of combustion gases or dust.