Dextromethorphan Hydrobromide (Dextromethorphan HBr)
Dextromethorphan Hydrobromide (Dextromethorphan HBr) is a synthetic derivative of morphinan and a widely used antitussive agent that suppresses cough reflex. It acts centrally on the cough center in the medulla without causing typical opioid side effects such as analgesia or dependence. It is commonly formulated in syrups, tablets, lozenges, and combination cold and flu medications. Due to its rapid onset, good oral bioavailability, and well-tolerated safety profile, Dextromethorphan HBr is a preferred active pharmaceutical ingredient (API) in cough suppressant products worldwide.