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LABORATORY GRADE

Ammonium Acetate Extra Pure

Ammonium Acetate Extra Pure is a high-purity, white crystalline solid that is highly soluble in water and commonly used as a buffer component in laboratory and analytical chemistry. It is especially valuable in high-performance liquid chromatography (HPLC), mass spectrometry, and biochemical assays where pH control and minimal ionic interference are essential. This compound also serves as a reagent in organic synthesis, particularly in the preparation of acetamides and other nitrogen-containing compounds. Its extra pure grade ensures excellent consistency, low contaminant levels, and compatibility with sensitive instrumentation. To maintain stability and prevent moisture absorption, it should be stored in a tightly sealed container in a cool, dry environment.

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Description

USES

Primary Uses

  1. Buffer Preparation in Analytical Chemistry

    • Widely used to prepare acetate buffer systems for pH control in HPLC, electrophoresis, and titrations.

  2. Reagent in Mass Spectrometry (LC-MS/HPLC-MS)

    • Acts as a volatile buffer component in mobile phases for mass spectrometric detection of biomolecules.

  3. Protein and Enzyme Studies

    • Maintains pH in biochemical assays and enzyme activity studies, particularly in low-salt conditions.

  4. Precursor in Organic Synthesis

    • Used in the synthesis of diazomethane, acetamide, and other small organic molecules in research labs.

  5. Salt for Ionic Strength Control

    • Adjusts ionic strength in analytical solutions, helping stabilize reaction conditions in titrations and calibrations.

Secondary Uses

  1. Reagent for Molecular Biology Workflows

    • Sometimes used in nucleic acid purification protocols to precipitate DNA or RNA under specific conditions.

  2. Study of Salt Hydrolysis and Buffer Systems

    • Ideal for demonstrating the behavior of weak acid/base salts and their buffering capacity in educational labs.

  3. Chromatographic Additive in Ion-Exchange Studies

    • Helps in pH modulation and ion interaction in experimental ion-exchange chromatography systems.

  4. Volatile Salt in Sample Preparation

    • Leaves minimal residue after drying—useful when samples need to be lyophilized or evaporated post-treatment.

  5. Decomposition and Thermal Stability Testing

    • Used in thermogravimetric studies to observe salt decomposition and volatilization behavior.
Additional information
AVAILABLE GRADES

LABORATORY GRADE,
PACK SIZE AVERAGE

Plastic Tin ( 20g- 500g)
AVAILABLE TEXTURES

Crystalline – Structured, geometric solids (e.g., sugar, citric acid crystals).
KEY ATTRIBUTES

1. Basic Identification Attributes

  • Chemical Name: Ammonium Acetate

  • CAS Number: 631-61-8

  • HS Code: 29152990 (Other salts of acetic acid)

  • Molecular Formula: Câ‚‚H₇NOâ‚‚ or CH₃COONHâ‚„

  • Synonyms:

    • Acetic acid, ammonium salt

    • Ethanoic acid ammonium salt

    • Ammonium ethanoate

    • NHâ‚„OAc

2. Physical & Chemical Properties

  • Physical State: Solid (crystalline powder or granules)

  • Color & Odor: White crystals; faint acetic odor

  • Boiling Point: Decomposes before boiling

  • Melting Point: ~114°C (with decomposition)

  • Density/Specific Gravity: ~1.17 g/cm³

  • Solubility:

    • Water: Very soluble (~148 g/100 mL at 25°C)

    • Alcohol: Soluble

  • pH Level: ~6.6–7.0 (5% solution in water)

  • Vapor Pressure: Negligible (non-volatile solid)

  • Flash Point: Not flammable

  • Autoignition Temperature: Not applicable

  • Viscosity: Not applicable (solid)

3. Safety & Hazard Attributes

  • Hazard Class (GHS):

    • Not classified as hazardous under normal laboratory conditions

    • May cause mild irritation to eyes or respiratory tract (dust)

  • NFPA Ratings:

    • Health: 1

    • Flammability: 0

    • Reactivity: 0

  • Exposure Limits:

    • No specific OSHA or ACGIH limits

    • General nuisance dust limit applies

  • Reactivity:

    • Reacts with strong acids (may release acetic acid fumes)

    • Decomposes on heating to form acetamide and water

4. Storage & Handling Attributes 

  • Storage Conditions:

    • Store in a cool, dry, well-ventilated area

    • Keep tightly sealed to prevent absorption of moisture (hygroscopic)

  • Incompatible Materials:

    • Strong acids, strong oxidizers, nitrates

  • Container Type:

    • HDPE or amber glass containers

  • Shelf Life & Expiration Date:

    • Typically 2 years in sealed containers

  • Special Handling Requirements:

    • Avoid inhalation of dust

    • Use gloves and goggles; handle under fume hood if heating

5. Regulatory & Compliance Attributes

  • Regulatory Status:

    • Listed under TSCA, REACH, and other global inventories

  • Hazard Symbols (GHS Pictograms):

    • None required

  • Transportation Restrictions:

    • Not classified as hazardous for transport

  • Waste Disposal Method:

    • Dissolve in water and neutralize if necessary

    • Dispose of according to local non-hazardous chemical waste protocols

6. Environmental & Health Impact

  • Ecotoxicity:

    • Low; readily biodegradable

    • Ammonium ions may affect aquatic life at high concentrations

  • Persistence in Environment:

    • Rapidly dissociates into ammonium and acetate ions

  • Carcinogenicity/Mutagenicity:

    • Not classified as carcinogenic or mutagenic

  • Biodegradability:

    • Fully biodegradable in soil and water systems
SAFETY HANDLING PRECAUTIONS
  1. Personal Protective Equipment (PPE):

    • Wear a lab coat, chemical-resistant gloves (e.g., nitrile), and safety goggles.

    • Use a dust mask or respirator when handling powder or in poorly ventilated areas.

  2. Handling:

    • Avoid contact with skin, eyes, and clothing.

    • Minimize dust generation and accumulation.

    • Handle in a well-ventilated laboratory or under a fume hood.

    • Keep away from incompatible materials like strong oxidizers and acids.

  3. Storage:

    • Store in a tightly sealed container in a cool, dry, well-ventilated area.

    • Protect from moisture—ammonium acetate is hygroscopic and may clump if exposed to air.

    • Keep separate from strong oxidizing agents and strong acids.

  4. Hygiene Measures:

    • Wash hands thoroughly after handling.

    • Avoid eating, drinking, or smoking in the lab.

    • Clean up spills promptly to avoid exposure.

FIRST AID MEASURES 

  1. Inhalation:

    • Move the person to fresh air.

    • If breathing is difficult or irritation occurs, seek medical attention.

    • Rinse nose and mouth with water if needed.

  2. Skin Contact:

    • Wash skin with soap and plenty of water.

    • Remove contaminated clothing and shoes.

    • Get medical help if irritation develops or persists.

  3. Eye Contact:

    • Rinse cautiously with water for at least 15 minutes.

    • Keep eyelids open and remove contact lenses if easy to do.

    • Seek medical advice if irritation persists.

  4. Ingestion:

    • Rinse mouth with water.

    • Do not induce vomiting.

    • If conscious, give water to dilute.

    • Seek medical attention, especially if symptoms occur.

FIRE FIGHTING MEASURES

  1. Suitable Extinguishing Media:

    • Use water spray, dry chemical powder, alcohol-resistant foam, or carbon dioxide (COâ‚‚).

  2. Specific Hazards:

    • Not highly flammable, but decomposes upon heating to produce irritating fumes such as ammonia and acetic acid vapors.

    • Fire can intensify in the presence of strong oxidizers.

  3. Protective Equipment for Firefighters:

    • Wear full protective gear and a self-contained breathing apparatus (SCBA).

  4. Firefighting Instructions:

    • Cool fire-exposed containers with water spray.

    • Avoid inhaling fumes.

    • Contain water runoff to prevent environmental contamination.

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