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LABORATORY GRADE

Diethyl Ether Extra Pure

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SHORT DESCRIPTION

Diethyl Ether Extra Pure is a volatile, highly flammable solvent widely used in laboratory settings for extractions, recrystallization, and as a reaction medium in organic synthesis. Its low boiling point and high volatility make it ideal for evaporative processes and rapid solvent removal. In analytical labs, it is commonly employed for liquid-liquid extraction due to its excellent miscibility with a variety of organic compounds. This extra pure grade ensures minimal impurities, making it suitable for sensitive chemical reactions and research applications. Proper storage in a tightly sealed, cool, and well-ventilated area is essential to maintain stability and safety.

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Description

USES

Table of Contents

Primary Uses 

  1. Solvent in Organic Reactions

    • Widely used as a non-polar solvent for Grignard reactions, extractions, and recrystallizations.

  2. Reagent Preparation & Purification

    • Common for dissolving fats, oils, waxes, and alkaloids during sample purification and separation techniques.

  3. Anaesthetic Research

    • Historically important in anesthesia studies, still referenced in pharmacological lab simulations (non-clinical use only).

Secondary Uses

  • Chromatography – Employed in TLC or column chromatography as an eluent or co-solvent.

  • Microbiology – Occasionally used for lipid extraction from microbial biomass.

  • Demonstration Labs – Its high volatility and flammability are useful for combustion experiments and evaporation studies.

KEY PRODUCT FEATURES

KEY ATTRIBUTES

1. Basic Identification Attributes

  • Chemical Name: Diethyl Ether

  • Other Names: Ethyl ether, Ether

  • Chemical Formula: C₄H₁₀O

  • CAS Number: 60-29-7

  • Grade: Extra Pure (Laboratory Grade)

  • Molecular Weight: 74.12 g/mol

  • Appearance: Clear, colorless volatile liquid

  • Odor: Sweet, characteristic ether-like

2. Physical & Chemical Properties

  • Boiling Point: 34.6 °C

  • Melting Point: -116.3 °C

  • Density: 0.713 g/cm³ at 20 °C

  • Solubility: Slightly soluble in water; miscible with alcohol, chloroform, and many organic solvents

  • Vapor Pressure: ~440 mmHg at 20 °C

  • Flash Point: -45 °C (closed cup)

  • Autoignition Temperature: ~160 °C

  • Flammability: Extremely flammable

3. Safety & Hazard Attributes

  • GHS Classification:

    • Flammable Liquids (Category 1)

    • Narcotic Effects (Category 3)

    • Peroxide Former (Dangerous on prolonged exposure to air)

  • Hazard Statements:

    • H224: Extremely flammable liquid and vapor

    • H336: May cause drowsiness or dizziness

    • EUH019: May form explosive peroxides

  • PPE Requirements:

    • Flame-resistant lab coat

    • Nitrile gloves

    • Chemical splash goggles

    • Use only in fume hood

  • First Aid:

    • Inhalation: Move to fresh air, administer oxygen if needed

    • Skin Contact: Wash thoroughly with soap and water

    • Eye Contact: Rinse immediately with plenty of water

    • Ingestion: Do NOT induce vomiting; seek immediate medical attention

4. Storage & Handling Attributes

  • Storage Conditions:

    • Store in tightly sealed containers under inert gas (nitrogen/argon)

    • Keep in a cool, dry, well-ventilated, flame-proof storage area

    • Protect from light and air (to avoid peroxide formation)

  • Stability Note:

    • Diethyl ether forms explosive peroxides on standing—test regularly

    • Store with added stabilizers unless specifically unstabilized

5. Regulatory & Compliance Attributes

  • EC Number: 200-467-2

  • UN Number: UN 1155

  • Hazard Class (Transport): Class 3 (Flammable Liquids)

  • Packing Group: I (high danger)

  • REACH Registration: Registered

  • DOT Classification (US): Flammable liquid

6. Laboratory Applications

  • Primary Uses:

    • Widely used as an organic solvent in labs

    • Extraction of organics from aqueous solutions

    • Grignard and other anhydrous reactions

    • Recrystallization and purification processes

  • Other Uses:

    • Historical use as an anesthetic (no longer recommended)

    • Cooling baths with dry ice

    • Precursor or diluent in reagent preparation
SAFETY HANDLING PRECAUTIONS

SECURITY MEASURES

LABORATORY SAFETY & HANDLING

  • PPE Required:

    • Flame-resistant lab coat

    • Nitrile or neoprene gloves

    • Chemical splash goggles

    • Work in a fume hood only

  • Storage Guidelines:

    • Store in tightly sealed containers under inert atmosphere (e.g., nitrogen)

    • Keep in flammable solvent cabinets, away from heat, sparks, or open flames

    • Protect from light to avoid peroxide formation

    • Avoid long-term storage: test for peroxides periodically

  • Handling Tips:

    • Ground and bond containers when dispensing

    • Never heat in open containers

    • Avoid contact with strong oxidizers and acids

FIRST AID MEASURES

  • Inhalation: Move to fresh air immediately; provide oxygen if needed

  • Skin Contact: Wash with soap and water

  • Eye Contact: Rinse thoroughly for 15 minutes and seek medical help

  • Ingestion: Do not induce vomiting; get emergency medical assistance

FIRE SAFETY MEASURES

  • Fire Hazard: Extremely flammable – forms explosive vapors

  • Explosion Risk: Vapor can travel far to an ignition source

  • Extinguishing Agents: Dry chemical, foam, or CO₂ (never use water directly)

  • Combustion Products: CO, CO₂, potentially irritating vapors

 

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