

Dioctyl Phthalate (DOP)
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Dioctyl phthalate (DOP) is a clear, colorless liquid with a slightly fruity odor. It is a commonly used industrial chemical and a type of phthalate ester, which is a plasticizer. DOP is often added to plastics, such as polyvinyl chloride (PVC), to make them more flexible and easier to process. It is also used as a solvent and a lubricant in a variety of industrial and consumer applications. However, due to concerns about its potential health and environmental effects, DOP is being replaced by other plasticizers in many applications.
Dioctyl phthalate (DOP) Uses
Primary uses of Dioctyl phthalate (dop)
1. PVC Plasticizer
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Flexible PVC Products:
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Vinyl flooring, cables, hoses, and synthetic leather (imparts softness and elasticity).
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Medical tubing & blood bags (though being phased out due to toxicity concerns).
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Inflatable products (toys, rafts, mattresses).
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Films & Coatings:
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Used in food packaging films, adhesive tapes, and waterproof coatings.
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2. Rubber Industry
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Improves flexibility in synthetic rubber products (e.g., gaskets, seals, shoe soles).
3. Adhesives & Sealants
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Enhances viscosity and flexibility in paints, glues, and caulks.
4. Printing Inks & Dyes
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Acts as a solvent and carrier in inks for textiles and packaging.
5. Automotive Components
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Used in car interiors (dashboards, seat covers), wiring insulation, and undercoating.
Secondary Uses of Dioctyl Phthalate (DOP/DEHP)
1. Cosmetics & Fragrances (Historically, Now Restricted)
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Once used as a solvent/fixative in perfumes and lotions (now banned in many countries).
2. Pesticide Formulations
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Helps dissolve and stabilize agricultural chemicals.
3. Lubricants & Hydraulic Fluids
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Used in industrial lubricants for machinery.
4. Laboratory & Chemical Research
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Occasionally used as a reference standard in chromatography.
5. Artificial Leather & Upholstery
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Found in fake leather products (e.g., furniture, car seats).
- Basic Identification Attributes
- Chemical Name (IUPAC): Bis(2-ethylhexyl) benzene-1,2-dicarboxylate
- Common/Trade Names:
- Dioctyl phthalate (DOP)
- Di(2-ethylhexyl) phthalate (DEHP)
- Bisoflex 81
- Octoil
- CAS Number: [117-81-7]
- HS Code: 2917.32.00 (Phthalic acid esters)
- Molecular Formula: C₂₄H₃₈O₄
- Synonyms:
- DEHP
- DOP
- 1,2-Benzenedicarboxylic acid, dioctyl ester
- Ethylhexyl phthalate
- Physical & Chemical Properties
- Physical State: Clear, oily liquid
- Color & Odor: Colorless to pale yellow; faint ester-like odor
- Boiling Point: 386 °C (727 °F)
- Melting Point: -50 °C (-58 °F)
- Density: 0.986 g/cm³ at 20 °C
- Solubility:
- Insoluble in water (<0.01 g/L at 25 °C)
- Miscible with most organic solvents (ethanol, acetone, benzene)
- pH Level: Neutral (~7)
- Vapor Pressure: 1.42 × 10⁻⁶ mmHg at 25 °C (low volatility)
- Flash Point: 207 °C (405 °F) (combustible but not highly flammable)
- Autoignition Temperature: 390 °C (734 °F)
- Viscosity: 56.7 cP at 25 °C (similar to light machine oil)
- Safety & Hazard Attributes
- Hazard Class (GHS):
- Reproductive Toxicity (Category 1B) (H360: May damage fertility or unborn child)
- Environmental Hazard (Aquatic Chronic 2) (H411: Toxic to aquatic life with long-lasting effects)
- NFPA Ratings:
- Health: 2 | Flammability: 1 | Reactivity: 0
- Exposure Limits:
- OSHA PEL: 5 mg/m³ (8-hour TWA for airborne dust/mist)
- ACGIH TLV: 5 mg/m³ (respirable fraction)
- Reactivity:
- Stable under normal conditions.
- Avoid strong oxidizers (e.g., peroxides, nitric acid).
- Storage & Handling Attributes
- Storage Conditions:
- Store in a cool, dry, well-ventilated area away from heat/open flames.
- Keep containers tightly sealed to prevent moisture absorption.
- Incompatible Materials: Strong acids, bases, oxidizers.
- Container Type:
- High-density polyethylene (HDPE) or stainless steel.
- Avoid PVC (can leach plasticizers).
- Shelf Life: Indefinite if stored properly (check for discoloration).
- Special Handling:
- Wear nitrile gloves, safety goggles, and chemical-resistant clothing.
- Use local exhaust ventilation to control airborne levels.
- Regulatory & Compliance Attributes
- Regulatory Status:
- EPA: Listed as a Hazardous Air Pollutant (HAP) under Clean Air Act.
- REACH: Restricted (Annex XVII) due to reproductive toxicity.
- EU: Banned in toys/childcare articles (Directive 2005/84/EC).
- FDA: Restricted in food packaging (21 CFR 175.105).
- Hazard Symbols (GHS):
- ⚠️ (Health hazard)
- 🌊 (Environmental hazard)
- Transportation Restrictions:
- UN Number: 3082 (Environmentally hazardous substance, liquid, n.o.s.)
- Packing Group: III (Low hazard for transport).
- Waste Disposal:
- Incinerate or dispose via licensed hazardous waste facilities (EPA/RCRA).
- Environmental & Health Impact
- Ecotoxicity:
- Aquatic Toxicity: LC50 (fish): 0.1–10 mg/L (highly toxic).
- Biodegradability: Not readily biodegradable (persistent).
- Persistence:
- Half-life in water: >100 days; adsorbs to sediments.
- Carcinogenicity/Mutagenicity:
- IARC: Group 2B (Possibly carcinogenic to humans).
- NTP: Reasonably anticipated to be a human carcinogen.
- Human Health:
- Endocrine disruptor (affects reproductive system).
- Chronic exposure linked to liver/kidney damage.
Personal Protective Equipment (PPE):
- Gloves:Nitrile or neoprene gloves (resistant to organic solvents).
- Eye Protection:Chemical safety goggles or face shield.
- Clothing:Lab coat or chemical-resistant apron.
- Respiratory Protection:Use a NIOSH-approved organic vapor respirator if ventilation is insufficient.
Handling & Storage:
- Use in a well-ventilated area(avoid inhalation of vapors/mist).
- Avoid skin and eye contact—DOP can be absorbed through skin.
- Store in tightly sealed containersaway from heat, sparks, and open flames.
- Keep away from strong oxidizers, acids, and bases.
Hygiene Practices:
- Wash hands thoroughly after handling.
- Do not eat, drink, or smoke near DOP.
Inhalation:
- Move to fresh air
- If breathing is difficult, provide oxygen and seek medical attention.
Skin Contact:
- Remove contaminated clothing.
- Wash affected area with soap and waterfor at least 15 minutes.
- If irritation persists, seek medical help.
Eye Contact:
- Rinse eyes with lukewarm waterfor at least 15 minutes, holding eyelids open.
- Seek immediate medical attentionif irritation continues.
Ingestion:
- Do NOT induce vomiting(risk of aspiration).
- Rinse mouth with water and give 200-300 mL of waterto drink if conscious.
- Seek emergency medical help(may cause gastrointestinal irritation).
Flammability:
- Combustible liquid(Flash Point: ~200°C / 392°F).
- Burns with thick, black smokeand may release toxic fumes (CO, CO₂, phthalic acid derivatives).
Extinguishing Media:
- Dry chemical powder, CO₂, foam, or water spray.
- For large fires, use alcohol-resistant foam.
Firefighting Procedures:
- Wear self-contained breathing apparatus (SCBA)and full protective gear.
- Cool containers with water sprayto prevent explosion.
- Avoid runoff contamination (environmental hazard).
Spill/Leak Response:
- Contain spill with inert absorbents(e.g., sand, vermiculite).
- Avoid washing into drains (DOP is toxic to aquatic life).
- Dispose of as hazardous wasteper local regulations.
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