HPMC Vivapharm
Whatsapp Order
HPMC Vivapharm is a high-quality, pharmaceutical-grade hydroxypropyl methylcellulose polymer widely used as an excipient and functional ingredient. It appears as a fine, white to off-white, odorless powder with excellent solubility in cold water and forms clear, viscous solutions. This cellulose ether derivative offers excellent film-forming, thickening, emulsifying, and controlled-release properties. Vivapharm E50 is prized in pharmaceutical, food, and cosmetic industries for its versatility, stability, and safety profile.
Description
Table of Contents
Toggle
HPMC Vivapharm
Primary UsesÂ
- Pharmaceutical Industry
- Used as a tablet binder and film former in oral solid dosage forms to improve tablet integrity and controlled drug release.
- Acts as a matrix former in sustained-release formulations, providing controlled dissolution profiles for active pharmaceutical ingredients.
- Functions as a disintegrant or swellable excipient to facilitate tablet disintegration where required.
- Utilized as a suspending agent and viscosity enhancer in liquid oral formulations and ophthalmic preparations.
- Serves as a protective coating agent for tablets and capsules to mask taste and improve stability.
- Food Industry
- Employed as a thickener, stabilizer, and emulsifier in sauces, dressings, bakery products, and dairy alternatives.
- Used as a gluten substitute or additive in gluten-free baked goods to improve texture and moisture retention.
- Enhances mouthfeel and shelf-life in low-fat and reduced-calorie food formulations.
- Cosmetics and Personal Care
- Functions as a thickening agent and film former in lotions, creams, shampoos, and conditioners.
- Provides stabilization in emulsions and suspensions, preventing ingredient separation.
- Used in hair gels and styling products for desired viscosity and texture.
- Industrial Applications
- Acts as a rheology modifier in paints, adhesives, and printing inks to control flow properties.
- Used in construction materials such as tile adhesives and cementitious coatings to improve workability and water retention.
Secondary UsesÂ
- Biomedical Research
- Used as a hydrogel base for drug delivery and tissue engineering studies.
- Employed in cell culture media as a viscosity modifier.
- Agriculture
- Utilized as a carrier or binder in pesticide formulations to improve adhesion and controlled release.
- Packaging
- Incorporated into biodegradable films and edible coatings for food packaging applications.
KEY ATTRIBUTES
- Basic Identification Attributes
- Chemical Name (IUPAC): Hydroxypropyl methylcellulose
- Common/Trade Name: HPMC Vivapharm E50
- CAS Number: 9004-65-3
- HS Code: 3912.90.00
- Molecular Formula: C56H108O30 (approximate polymer unit)
- Synonyms: Hypromellose; Methylhydroxypropyl cellulose; Methocel E50
- Physical & Chemical Properties
- Physical State: Fine powder
- Color & Odor: White to off-white; odorless
- Viscosity (2% aqueous solution): ~50 mPa·s at 20°C
- Solubility: Soluble in cold water, insoluble in hot water and organic solvents
- pH (1% solution): Neutral to slightly alkaline (6.5–8.5)
- Thermal Stability: Stable up to ~200°C
- Film-Forming Ability: Excellent, clear films upon drying
- Safety & Hazard Attributes
- GHS Classification: Non-hazardous; Generally Recognized As Safe (GRAS)
- Toxicity: Non-toxic and non-irritant at typical use levels
- Exposure Limits: No specific occupational exposure limits
- Storage & Handling Attributes
- Container Type: Sealed polyethylene bags or drums with moisture barrier
- Storage Conditions: Store in cool, dry place away from moisture and direct sunlight
- Shelf Life: Up to 36 months if stored properly
- Handling Notes: Avoid dust generation; use dust masks in bulk handling
- Regulatory & Compliance Attributes
- Approved for pharmaceutical use by USP, EP, JP
- Food additive status approved by FDA (E464) and EFSA
- Complies with REACH and other global chemical regulations
- Environmental & Health Impact
- Biodegradability: Biodegradable under aerobic conditions
- Ecotoxicity: Low environmental toxicity
- Bioaccumulation: Not expected to bioaccumulate
- Carcinogenicity/Mutagenicity: Not classified
SAFETY HANDLING PRECAUTIONS
- Safety Handling Precautions
- PPE Required: Dust mask, gloves, and safety goggles recommended during powder handling
- Handling Guidelines: Use in well-ventilated areas; avoid dust accumulation
- Hygiene Practices: Wash hands after handling; avoid inhalation of dust
- First Aid Measures
- Inhalation: Move to fresh air if respiratory irritation occurs
- Skin Contact: Wash with soap and water if irritation develops
- Eye Contact: Rinse thoroughly with water for 15 minutes; seek medical advice if irritation persists
- Ingestion: Generally regarded as safe; seek medical advice if excessive ingestion occurs
- Firefighting Measures
- Fire Hazards: Non-flammable, but may burn under extreme heat
- Extinguishing Media: Water spray, foam, dry chemical, or COâ‚‚
- Special Precautions: Avoid inhalation of smoke from burning material
- Combustion Products: Carbon oxides and other organic compounds
Related products
Ceteareth 20 Ginonic CSA 20
Ceteareth 20 Ginonic CSA 20 is a nonionic surfactant and emulsifier derived from the ethoxylation of cetearyl alcohol, incorporating approximately 20 ethylene oxide units per molecule. It appears as a white to off-white waxy solid or viscous liquid, depending on temperature and formulation. This emulsifier is widely used in cosmetic, pharmaceutical, and industrial formulations for its excellent ability to stabilize oil-in-water emulsions, improve texture, and enhance the sensory properties of finished products. Its high hydrophilic-lipophilic balance (HLB) makes it especially effective in forming stable emulsions and solubilizing lipophilic ingredients in aqueous phases. Ceteareth 20 is valued for its mildness, broad compatibility, and multifunctional performance.
Ceteareth 25 Ginonic CSA 25
Ceteareth 25 Ginonic CSA 25 is a nonionic surfactant and emulsifier derived from the ethoxylation of cetearyl alcohol, incorporating approximately 20 ethylene oxide units per molecule. It appears as a white to off-white waxy solid or viscous liquid, depending on temperature and formulation. This emulsifier is widely used in cosmetic, pharmaceutical, and industrial formulations for its excellent ability to stabilize oil-in-water emulsions, improve texture, and enhance the sensory properties of finished products. Its high hydrophilic-lipophilic balance (HLB) makes it especially effective in forming stable emulsions and solubilizing lipophilic ingredients in aqueous phases. Ceteareth 20 is valued for its mildness, broad compatibility, and multifunctional performance.
Cetyl Alcohol
Cetyl Alcohol, also known as 1-Hexadecanol or Palmityl Alcohol, is a fatty alcohol derived primarily from natural sources such as palm oil and coconut oil. It appears as a waxy, white to pale yellow solid with a faint fatty odor. Cetyl Alcohol is widely used in cosmetic, pharmaceutical, and industrial formulations due to its emollient, emulsifying, thickening, and stabilizing properties. It helps improve texture, consistency, and moisturizing effects in personal care products. Cetyl Alcohol is compatible with many ingredients, making it a versatile multifunctional ingredient.
Dimethicone Silicon Oil
Dimethicone Silicon Oil, also known as polydimethylsiloxane (PDMS) or silicone oil, is a clear, odorless, and non-volatile silicone-based polymer widely used for its lubricating, anti-foaming, water-repellent, and skin-conditioning properties. It is a linear silicone polymer composed of repeating dimethylsiloxane units. Dimethicone exhibits excellent thermal stability, chemical inertness, and low surface tension, making it highly versatile in pharmaceutical, cosmetic, personal care, industrial, and food applications. It is available in various viscosities, from very low to high viscosity oils, enabling tailored formulations.
Fish Collagen
Fish Collagen is a natural protein derived from the skin, scales, and bones of various fish species through enzymatic hydrolysis or acid extraction. It is predominantly Type I collagen, known for its excellent bioavailability and biocompatibility. Fish Collagen typically appears as a fine white to off-white powder with low odor and high solubility in water and acidic solutions. It is widely prized in cosmetics, nutraceuticals, pharmaceuticals, and food industries due to its superior absorption compared to mammalian collagen, making it highly effective in skin, joint, and bone health applications. Fish Collagen supports the body’s extracellular matrix, promoting skin elasticity, hydration, and tissue repair.
Hycryl
Hycryl is a specialized acrylic copolymer resin designed primarily for industrial and cosmetic applications. It appears as a white to off-white powder or granules with excellent film-forming, adhesive, and thickening properties. Known for its compatibility with a wide range of solvents and plasticizers, Hycryl 77 provides excellent clarity, flexibility, and durability in coatings, adhesives, and personal care formulations. Its balanced molecular weight and functional groups enable it to deliver strong binding and aesthetic properties in both aqueous and solvent-based systems.
Hydroxyethyl Cellulose
Hydroxyethyl Cellulose , marketed under brand names such as Natrosol, is a non-ionic, water-soluble polymer derived from cellulose by reacting alkali cellulose with ethylene oxide. It appears as a white to off-white, free-flowing powder with excellent thickening, binding, and film-forming properties. HEC is widely used as a rheology modifier and stabilizer due to its high water retention, solubility, and compatibility with a broad range of ingredients. It is valued in many industries including cosmetics, pharmaceuticals, paints, adhesives, and personal care products.
Inosoft Softener Flakes
Inosoft Softener Flakes is a solid, flaked fabric softener designed for use in textile finishing processes. These flakes are typically composed of cationic softening agents derived from quaternary ammonium compounds or fatty amine derivatives, formulated to impart softness, smoothness, and antistatic properties to fabrics. The flaked form allows for easy storage, handling, and controlled dosing in industrial textile softening applications. Inosoft flakes dissolve readily in water during processing to provide uniform softening and enhanced fabric feel.