Polyethylene Glycol (PEG 6000)
Polyethylene Glycol 6000 (PEG 6000) is a high-molecular-weight polymer derived from ethylene oxide. It appears as a white, waxy solid or flake and is non-toxic, water-soluble, and chemically stable. PEG 6000 is widely used in pharmaceuticals, cosmetics, food processing, industrial formulations, and biotechnology, valued for its lubricating, solubilizing, binding, and moisturizing properties. It is odorless and tasteless, making it suitable for sensitive formulations.
lsions and improves product consistency.
Food Industry
Used as a processing aid, carrier, or anti-caking agent in food additives.
May be found in confectionery coatings, chewing gums, and bakery items.
Recognized as safe (GRAS) for indirect food contact applications.
Industrial Applications
Employed as a mold release agent and lubricant in plastic and rubber processing.
Used as an anti-static and anti-dust agent in powder formulations.
Functions as a dispersant and lubricant in textile and leather finishing.
Biotechnology & Laboratory Use
Commonly used for protein precipitation and DNA purification.
Acts as a crowding agent in cell fusion and virus precipitation.
Serves as a medium for enzyme storage and protein stabilization.
Secondary Uses
Paints and Coatings
Used to improve flow, leveling, and flexibility in water-based paints and coatings.
Printing Inks & Toners
Functions as a binder and viscosity regulator for better print quality and stability.
Ceramics and Construction
Acts as a binder and plasticizer in ceramic slurries and dry mix mortars.
Improves workability and water retention.
Agricultural Chemicals
Used as a carrier and wetting agent in pesticide and fertilizer formulations.
Adhesives and Sealants
Improves flexibility and tack in hot-melt adhesives and sealant compositions.
Basic Identification Attributes
Chemical Name (IUPAC): Poly(oxy-1,2-ethanediyl), α-hydro-ω-hydroxy-
Common/Trade Name: PEG 6000
CAS Number: 25322-68-3
HS Code: 3907.20.00 (Polyethylene glycol and derivatives)
Synonyms: Polyethylene oxide; Macrogol 6000
Physical & Chemical Properties
Physical State: Solid (flakes or powder)
Color & Odor: White; odorless
Solubility: Completely soluble in water and alcohol
Melting Point: 55–63°C
Molecular Weight: Approx. 6,000 g/mol
Viscosity (25°C, 20% solution): 90–130 cP
pH (5% solution): 4.5–7.5
Safety & Hazard Attributes
GHS Classification: Not classified as hazardous
Toxicity: Non-toxic; safe for topical, oral, and parenteral use
Allergen Status: Hypoallergenic
Inhalation: Low risk; avoid excessive dust exposure
Storage & Handling Attributes
Storage Conditions: Store in a dry, cool, well-ventilated area away from moisture and heat
Container Type: Typically supplied in 25kg kraft paper bags or fiber drums with liners
Shelf Life: Up to 3 years under proper storage conditions
Handling Precautions: Use gloves and dust mask during bulk handling; avoid contact with eyes
Regulatory & Compliance Attributes
Complies with:
USP/NF, Ph. Eur., JP (pharmaceutical grades)
FDA (GRAS for food contact and excipient use)
REACH and RoHS (industrial use)
ISO 9001 certified production
Environmental & Health Impact
Biodegradability: Biodegradable under aerobic conditions
Ecotoxicity: Low ecological risk
Bioaccumulation: Not expected
Allergenic Potential: None
Safety Handling Precautions
PPE Required: Gloves, safety glasses, dust mask (bulk use)
Handling Guidelines:
Minimize dust generation
Avoid ingestion or eye contact
Use in well-ventilated areas
Storage Measures: Keep sealed in moisture-proof containers
First Aid Measures
Inhalation: Move to fresh air; seek help if coughing or discomfort persists
Skin Contact: Wash with water and mild soap
Eye Contact: Rinse cautiously with water for 15 minutes
Ingestion: Rinse mouth with water; generally non-toxic, but consult a physician if large amounts are ingested
Firefighting Measures
Fire Hazards: Slightly combustible at high temperatures
Flash Point: >200°C
Extinguishing Media: Water spray, COâ‚‚, dry chemical, or foam
Special Precautions: Avoid dust cloud formation
Hazardous Combustion Products: Carbon dioxide, carbon monoxide