Sodium Dihydrogen Phosphate Extra Pure
Sodium Dihydrogen Phosphate Extra Pure is a white, water-soluble crystalline compound commonly used as a buffering agent in analytical and biochemical applications. It offers precise pH control in phosphate buffer systems, making it ideal for lab-scale titrations, enzyme reactions, and chromatography. Due to its high solubility and consistent purity, it is also widely used in pharmaceutical formulations, food processing (as E339), and electrolyte replacement therapies. Its Extra Pure grade ensures reliability in sensitive chemical and biological procedures.
Sodium Dihydrogen Phosphate Extra Pure
PRIMARY USES
Analytical Reagent & Laboratory Applications:
• Used as a buffering agent in analytical chemistry and biochemistry
• Applied in the preparation of phosphate buffer solutions with controlled pH
• Helps stabilize enzyme activity in biochemical assays
• Involved in titrations, electrophoresis, and chromatography applications
Pharmaceutical & Medical Formulations:
• Serves as a laxative or urinary acidifier in some medicinal products
• Functions as an excipient and buffering agent in injectable solutions
• Included in electrolyte replacement preparations and dialysis fluids
Food & Beverage Industry (regulated use):
• Acts as a pH stabilizer and acidity regulator (E339) in food processing
• Used in cheese making and meat curing to improve texture and moisture retention
• Prevents precipitation of metal ions in soft drinks and beverages
SECONDARY USES
Water Treatment:
• Functions as a corrosion inhibitor and metal ion sequestrant in water systems
• Adjusts water alkalinity and aids in pH stabilization of treated water
Textile & Dyeing Industry:
• Employed as a buffering salt during dyeing processes
• Enhances color fastness by controlling pH during fabric treatment
Agricultural & Soil Applications:
• Used as a source of phosphorus in specialty nutrient solutions for hydroponics and fertigation
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Basic Identification Attributes
• Chemical Name: Sodium Dihydrogen Phosphate
• CAS Number: 7558-80-7
• HS Code: 2835.12.00
• Molecular Formula: NaH₂PO₄
• Synonyms:
- Monosodium phosphate
- Sodium phosphate monobasic
- Monobasic sodium phosphate
- MSP
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Physical & Chemical Properties
Physical State: Solid (crystalline powder or granules)
• Color & Odor: White, odorless
• Melting Point: ~60 °C (dihydrate), decomposes at higher temperatures
• Density/Specific Gravity: ~2.04 g/cm³
• Solubility:
- Highly soluble in water (~85 g/100 mL at 20 °C)
- Insoluble in alcohol
• pH Level: ~4.5 to 5.5 (1% aqueous solution)
• Vapor Pressure & Volatility: Non-volatile
• Flash Point: Not applicable (non-flammable)
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Safety & Hazard Attributes
Hazard Class (GHS Classification):
- Not classified as hazardous under normal use
• NFPA Ratings: - Health: 1
- Flammability: 0
- Reactivity: 0
• Exposure Limits: - No established OSHA PEL or ACGIH TLV
• Reactivity: - Stable under normal conditions
- May react with strong oxidizers
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Storage & Handling Attributes
Storage Conditions:
- Store in a cool, dry, and well-ventilated place
- Keep container tightly closed to avoid moisture absorption
• Incompatible Materials: - Strong acids, strong bases, oxidizing agents
• Container Type: - HDPE, polyethylene-lined drums, or sealed containers
• Shelf Life & Expiration Date: - Stable for several years if stored properly
• Special Handling Requirements: - Avoid generating dust
- Use appropriate PPE when handling in bulk
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Regulatory & Compliance Attributes
Regulatory Status:
- GRAS (Generally Recognized As Safe) by the FDA for food use
- Approved under USP and FCC for pharmaceutical and food applications
• Transportation Restrictions: - Not classified as hazardous for transport
• Waste Disposal Method: - Dispose according to local environmental regulations
- Non-hazardous waste classification
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Environmental & Health Impact
Ecotoxicity:
- Low toxicity to aquatic life
• Persistence in Environment: - Phosphates may contribute to eutrophication in large quantities
• Carcinogenicity/Mutagenicity: - Not classified as carcinogenic or mutagenic
• Biodegradability:
- Inorganic compound; not biodegradable but readily assimilated in biological systems
SAFETY PRECAUTIONS
Personal Protective Equipment (PPE):
• Use chemical-resistant gloves (e.g., nitrile)
• Wear safety goggles or protective eyewear
• Use a lab coat or appropriate protective clothing
• Use dust mask if handling powder in bulk
Handling:
• Avoid inhalation of dust
• Wash hands thoroughly after handling
• Use with adequate ventilation
Storage:
• Store in sealed containers away from moisture and incompatible substances
• Keep in a dry, cool location
FIRST AID MEASURES
Inhalation:
• Move to fresh air
• Seek medical attention if breathing difficulty occurs
Skin Contact:
• Wash skin with soap and water
• Remove contaminated clothing
Eye Contact:
• Rinse with water for at least 15 minutes
• Seek medical advice if irritation persists
Ingestion:
• Rinse mouth with water
• Do not induce vomiting
• Seek medical attention if large quantities are ingested
FIRE FIGHTING MEASURES
Flammability:
• Not flammable
Extinguishing Media:
• Use appropriate media for surrounding fire (water, foam, dry chemical, CO₂)
Hazardous Combustion Products:
• May produce sodium oxides or phosphorus oxides if heated to decomposition
Firefighter Protection:
• Use full protective gear and SCBA in case of fire