Sulphadimidine Sodium BP

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Sulphadimidine Sodium BP is the sodium salt form of sulphadimidine, a synthetic sulfonamide antibacterial agent primarily used in veterinary and pharmaceutical applications. It offers improved solubility in water compared to the base form, making it suitable for injectable solutions, oral suspensions, and medicated feed additives. The British Pharmacopoeia (BP) grade assures pharmaceutical quality and purity for effective treatment of bacterial infections.

Description

Primary Uses
Veterinary Medicine
Antibacterial Agent: Used to treat respiratory, urinary tract, gastrointestinal, and soft tissue infections in livestock such as cattle, swine, and poultry.

Injectable Formulations: Commonly formulated as injectable solutions for rapid systemic treatment of bacterial infections.

Medicated Feeds and Water: Used as a water-soluble additive for prevention and control of infections in herd/flock management.

Human Medicine
Antimicrobial Agent: Occasionally used in human medicine for treatment of certain bacterial infections, especially in topical or oral suspension forms (subject to regulatory approval).

 

Secondary Uses
Aquaculture
Fish Health Management: Applied in fish farms to control bacterial infections under veterinary supervision.

Research & Development
Pharmaceutical Research: Used as a standard compound in studies on sulfonamide antibiotics and bacterial resistance mechanisms.

Formulation Development: Utilized in developing new veterinary and human pharmaceutical formulations.

PRODUCT KEY FEATURES

Basic Identification Attributes
Chemical Name (IUPAC): Sodium 4-amino-N-(4,6-dimethyl-2-pyrimidinyl)benzenesulfonamide

Common/Trade Name: Sulphadimidine Sodium BP

CAS Number: 144-82-1

HS Code: 2941.20.00

Synonyms: Sulphadimidine sodium salt, Sulfadimidine sodium

 

Physical & Chemical Properties
Physical State: White to pale yellow crystalline powder

Color & Odor: Off-white to yellow; odorless or faint sulfurous odor

Melting Point: 165–167 °C (decomposes)

Solubility: Highly soluble in water; soluble in alkaline solutions and ethanol

Density: Approx. 1.6 g/cm³

 

Safety & Hazard Attributes
GHS Classification: May cause allergic skin reactions; handle with care

Toxicity: Moderate toxicity; avoid inhalation and prolonged skin contact

Exposure Limits: No specific occupational exposure limits, but good industrial hygiene is recommended

 

Storage & Handling Attributes
Storage Conditions: Store in a cool, dry, well-ventilated area protected from light and moisture

Container Type: Sealed HDPE or glass containers

Shelf Life: 24 months under recommended conditions

Handling Precautions: Avoid dust generation; use appropriate PPE including gloves and masks

 

Regulatory & Compliance Attributes
Complies with British Pharmacopoeia (BP) veterinary and pharmaceutical standards

Manufactured under Good Manufacturing Practices (GMP)

Meets relevant veterinary and pharmaceutical regulatory requirements

 

Environmental & Health Impact
Biodegradability: Limited biodegradability; sulfonamides degrade slowly under aerobic conditions

Ecotoxicity: Potentially toxic to aquatic organisms; minimize environmental release

Bioaccumulation: Not significant

SAFETY HANDLING PRECAUTIONS

PPE Required: Gloves, protective clothing, and dust masks recommended

Handling Guidelines: Use in well-ventilated areas; avoid dust inhalation and skin contact

Storage Measures: Keep containers tightly closed and dry

 

First Aid Measures
Inhalation: Move to fresh air; seek medical attention if respiratory symptoms develop

Skin Contact: Wash thoroughly with soap and water; discontinue use if irritation occurs

Eye Contact: Flush eyes with water for at least 15 minutes; seek medical help if irritation persists

Ingestion: Rinse mouth and seek medical advice immediately

 

Firefighting Measures
Fire Hazards: Combustible solid

Extinguishing Media: Use water spray, foam, dry chemical, or COâ‚‚ extinguishers

Hazardous Combustion Products: Carbon oxides, nitrogen oxides, sulfur oxides