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Trisodium Citrate BP 98%

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Trisodium Citrate BP 98% is a high-purity, pharmaceutical-grade salt of citric acid, widely used for its buffering, alkalizing, and chelating properties. It is a white crystalline powder that dissolves readily in water, forming an alkaline solution. This compound is primarily utilized in pharmaceutical formulations as a buffering agent, anticoagulant, and alkalizer. It also finds extensive use in food, cosmetic, and industrial applications. The British Pharmacopoeia (BP) grade ensures compliance with stringent quality standards for medicinal and food-grade use.

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Description

Primary Uses
Pharmaceutical Industry:

Used as a buffering agent in intravenous solutions, oral rehydration salts, and pharmaceutical preparations to maintain pH stability.

Acts as an anticoagulant by chelating calcium in blood collection tubes and diagnostic applications.

Used in formulations to alkalinize urine in treatment of urinary tract infections and kidney stones.

Food Industry:

Employed as an acidity regulator, sequestrant, and flavor enhancer in beverages, dairy products, canned foods, and confections.

Functions as an emulsifier and preservative to improve texture and shelf life of processed foods.

Secondary Uses
Cosmetics and Personal Care:

Used as a pH adjuster and buffering agent in skin creams, lotions, and shampoos.

Industrial Applications:

Serves as a chelating agent in detergents and cleaning products to enhance cleaning efficiency by binding metal ions.

Laboratory Use:

Utilized as a reagent and buffer in biochemical and molecular biology research.

PRODUCT KEY FEATURES

Chemical Name (IUPAC): Trisodium 2-hydroxypropane-1,2,3-tricarboxylate

Common/Trade Name: Trisodium Citrate BP 98%

CAS Number: 6132-04-3

HS Code: 2918.16.00

Synonyms: Sodium citrate tribasic, trisodium citrate dihydrate (depending on hydration)

 

Physical & Chemical Properties
Physical State: White crystalline powder or granules

Color & Odor: White; odorless

Melting Point: Decomposes above 300 °C

Solubility: Highly soluble in water; insoluble in alcohol

pH: Alkaline aqueous solution (pH ~8.5–9.5)

 

Safety & Hazard Attributes
GHS Classification: Not classified as hazardous under normal handling

Toxicity: Low toxicity; generally recognized as safe (GRAS) in food and pharmaceuticals

Exposure Limits: No specific occupational exposure limits; follow standard hygiene practices

 

Storage & Handling Attributes
Storage Conditions: Store in a cool, dry, and well-ventilated area, protected from moisture and contaminants

Container Type: Sealed moisture-proof bags or drums

Shelf Life: Typically 24 months when stored under recommended conditions

Handling Precautions: Avoid dust formation and exposure to moisture

 

Regulatory & Compliance Attributes
Complies with British Pharmacopoeia (BP) standards

Manufactured under Good Manufacturing Practices (GMP)

Listed on regulatory inventories including TSCA, REACH, and FDA GRAS list

Approved for use in pharmaceutical, food, and cosmetic products

 

Environmental & Health Impact
Biodegradability: Biodegradable under aerobic conditions

Ecotoxicity: Low toxicity to aquatic organisms

Bioaccumulation: Not significant

SAFETY HANDLING PRECAUTIONS

PPE Required: Gloves, dust mask, and eye protection recommended during handling

Handling Guidelines: Use adequate ventilation; avoid dust inhalation

Storage Measures: Keep containers sealed and dry

 

First Aid Measures
Inhalation: Move to fresh air; seek medical attention if respiratory symptoms occur

Skin Contact: Wash with soap and water

Eye Contact: Rinse with plenty of water for at least 15 minutes; seek medical help if irritation persists

Ingestion: Rinse mouth; seek medical advice if adverse effects occur

 

Firefighting Measures
Fire Hazards: Non-flammable

Extinguishing Media: Use water spray, foam, or dry chemical extinguishers

Hazardous Combustion Products: May emit carbon oxides upon decomposition

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