Vitamin B2 (Riboflavin base)

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Vitamin B2 Riboflavin base, commonly known as Riboflavin Base, is a water-soluble vitamin essential for energy production, cellular function, and metabolism of fats, drugs, and steroids. It is a vital component of coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), which participate in numerous biological oxidation-reduction reactions. Riboflavin base is widely used in pharmaceuticals, food fortification, and dietary supplements.

Description

Vitamin B2 (Riboflavin base)

Primary Uses

  1. Pharmaceutical Industry
  • Nutritional Supplement: Used in tablets, capsules, and injections to prevent and treat riboflavin deficiency and related disorders such as ariboflavinosis.
  • Supportive Therapy: Included in B-complex vitamin formulations to enhance metabolic and enzymatic functions.
  1. Food & Beverage Industry
  • Fortification Agent: Added to cereals, dairy products, beverages, and infant formulas to improve nutritional value and prevent deficiencies.
  1. Nutraceuticals & Dietary Supplements
  • Used in multivitamin and B-complex supplements to promote energy metabolism, skin, eye health, and overall wellness.

Secondary Uses

  1. Animal Nutrition
  • Feed Additive: Supplemented in animal feed to support growth, reproductive health, and metabolic processes in livestock and pets.
  1. Cosmetics
  • Ingredient in skin care products for its antioxidant properties and to support healthy skin.
  1. Research & Development
  • Utilized in biochemical and clinical research focusing on vitamin metabolism and deficiency.
KEY PRODUCT FEATURES

1. Basic Identification Attributes

  • Chemical Name (IUPAC): 7,8-Dimethyl-10-(D-riboflavanosyl)isoalloxazine
  • Common/Trade Name: Riboflavin Base, Vitamin B2
  • CAS Number: 83-88-5
  • HS Code: 2936.21.00
  • Synonyms: Riboflavin, Vitamin B2, Lactoflavin

2. Physical & Chemical Properties

  • Physical State: Orange to reddish-orange crystalline powder
  • Color & Odor: Orange-red; odorless to faint odor
  • Solubility: Sparingly soluble in water; insoluble in organic solvents
  • Melting Point: 280 °C (decomposes)
  • Density: Approx. 1.6 g/cm³

3. Safety & Hazard Attributes

  • GHS Classification: Not classified as hazardous under normal conditions
  • Toxicity: Low toxicity; safe within recommended dosages
  • Exposure Limits: No specific occupational exposure limits established

4. Storage & Handling Attributes

  • Storage Conditions: Store in a cool, dry, dark place to prevent degradation by light
  • Container Type: Sealed, light-protective containers
  • Shelf Life: 24 months under proper storage conditions
  • Handling Precautions: Avoid dust generation and exposure to light

5. Regulatory & Compliance Attributes

  • Complies with USP, BP, and other relevant pharmacopeia standards
  • Manufactured under GMP to ensure quality and safety
  • Approved for use in pharmaceuticals, dietary supplements, and food fortification
  • Meets international regulatory requirements

6. Environmental & Health Impact

  • Biodegradability: Biodegradable under normal environmental conditions
  • Ecotoxicity: Low environmental impact
  • Bioaccumulation: Not significant
SAFETY HANDLING PRECAUTIONS

Safety Handling Precautions

  • PPE Required: Gloves and dust mask recommended during handling
  • Handling Guidelines: Use adequate ventilation; avoid inhalation of dust
  • Storage Measures: Keep containers tightly closed and protected from light

First Aid Measures

  • Inhalation: Move to fresh air; seek medical attention if irritation persists
  • Skin Contact: Wash thoroughly with soap and water
  • Eye Contact: Flush with water for 15 minutes; seek medical help if irritation continues
  • Ingestion: Rinse mouth; obtain medical advice if necessary

Firefighting Measures

  • Fire Hazards: Combustible but not highly flammable
  • Extinguishing Media: Water spray, foam, or dry chemical extinguishers
  • Hazardous Combustion Products: May produce carbon oxides and nitrogen oxides upon combustion