Acidulants
Antioxidants
Nutraceutical Ingredients (food)
Collectors
Dust Suppressants
Explosives and Blasting Agents
Flocculants and Coagulants
Frothers
Leaching Agents
pH Modifiers
Precious Metal Extraction Agents
Antioxidants(plastic)
Colorants (Pigments, Dyes)
Fillers and Reinforcements
Flame Retardants
Monomers
Plasticizers
Polymerization Initiators
Stabilizers (UV, Heat)
Antifoaming Agents
Chelating Agents
Coagulants and Flocculants
Corrosion Inhibitors
Disinfectants and Biocides
Oxidizing Agents
pH Adjusters
Scale Inhibitors( water)
Antioxidants(cosmetic)
Emollients
Fragrances and Essential Oils
Humectants
Preservatives
Surfactants(cosmetic)
Thickeners
UV Filters
Fertilizers
Soil Conditioners
Plant Growth Regulators
Animal Feed Additives
Biostimulants
Pesticides (Herbicides, Insecticides, Fungicides)
Active Pharmaceutical Ingredients (APIs)
Excipients
Solvents(pharmaceutical)
Antibiotics
Antiseptics and Disinfectants
Vaccine Adjuvants
Nutraceutical Ingredients (pharmaceutical)
Analgesics & Antipyretics
Analytical Reagents
Chromatography Chemicals
Spectroscopy Reagents
Molecular Biology Reagents
Biochemical Reagents
Inorganic and Organic Standards
Laboratory Safety Chemicals
Specialty Laboratory Chemicals(Special Laboratory Equipment)
Demulsifiers
Hydraulic Fracturing Fluids
Scale Inhibitors(oil)
Surfactants(oil)
Drilling Fluids
Dyes and Pigments
Bleaching Agents
Softening Agents
Finishing Agents
Antistatic Agents
Admixtures
Waterproofing Agents
Sealants and Adhesives
Curing Compounds
Concrete Repair Chemicals
Anti-Corrosion Coatings
Surfactants(cleaning)
Builders
Enzymes
Solvents (Cleaning)
Fragrances
Electronic Chemicals
Catalysts
Lubricants
Photographic Chemicals
Refrigerants
Automotive chemicals
Pyrotechnic Chemicals
Biodegradable Surfactants
Bio-based Solvents
Renewable Polymers
Carbon Capture Chemicals
Wastewater Treatment Chemicals
Pigments
Solvents(paint)
Specialty Coatings
Binders/Resins
Additives
Driers
Anti-Corrosion Agents
Functional Coatings
Application-Specific Coatings
Fresh Herbs
Ground Spices
Whole Spices
Spice Blends
Dried Herbs
Leavening Agents
Dough Conditioners
Flour Treatments
Fat Replacers
Decoratives
Preservatives(baking)
Plasticizers & Softeners
Reinforcing Agents
Adhesion Promoters
Vulcanizing Agents
Antidegradants
Blowing Agents
Fillers & Extenders
Accelerators & Retarders
Cross Carmellose Sodium BP
Whatsapp Order
Cross Carmellose Sodium BP (also known as Croscarmellose Sodium or CCS) is a cross-linked sodium carboxymethyl cellulose polymer. It is a highly efficient, super-disintegrant commonly used in pharmaceutical tablet and capsule formulations. This white to off-white, odorless, and tasteless powder exhibits excellent swelling properties and rapid water uptake, which facilitates fast tablet disintegration and improves drug bioavailability. It is chemically stable, non-toxic, and compatible with a wide range of active pharmaceutical ingredients (APIs).
Description
Cross Carmellose Sodium BP
Primary Uses
Pharmaceuticals
- Acts as a superdisintegrant in tablets and capsules to promote rapid break-up and dissolution, enhancing drug absorption.
- Used in direct compression and wet granulation tablet formulations for improved mechanical strength and disintegration efficiency.
- Utilized in orally disintegrating tablets (ODTs) and fast-dissolving formulations.
- Serves as a binder in controlled-release formulations to modify drug release profiles.
Personal Care & Cosmetics
- Employed as a thickener and stabilizer in topical gels and creams.
- Used to improve texture and moisture retention in skincare products.
Secondary Uses
Food Industry
- Occasionally used as a stabilizer or thickening agent in food processing (subject to regulatory approvals).
Industrial Applications
- Applied as a thickener, binder, and stabilizer in paints, adhesives, and detergents.
PRODUCT KEY FEATURES
1. Basic Identification Attributes
- Chemical Name (IUPAC): Cross-linked sodium carboxymethyl cellulose
- Common/Trade Name: Cross Carmellose Sodium, Croscarmellose Sodium, CCS
- CAS Number: 74811-65-7
- HS Code: 3912.90.00
- Molecular Formula: Variable (polymeric)
- Synonyms:
- Cross-linked sodium CMC
- Sodium carboxymethyl cellulose cross-linked
2. Physical & Chemical Properties
- Physical State: White to off-white powder
- Color & Odor: Odorless; tasteless
- Melting Point: Decomposes before melting
- Density: Approximately 0.4–0.6 g/cm³ (bulk density)
- Solubility:
- Insoluble in water, but swells rapidly to many times its weight
- Insoluble in organic solvents
- pH: Neutral to slightly alkaline in aqueous suspension (~6.5-8.0)
- Stability: Chemically stable; resistant to heat and pH variations
3. Safety & Hazard Attributes
- Hazard Class (GHS): Not classified as hazardous
- NFPA Ratings:
- Health: 0
- Flammability: 1 (combustible dust)
- Reactivity: 0
- Exposure Limits: No specific limits; minimize inhalation of dust
- Toxicity: Non-toxic; widely used in pharmaceutical applications
- Reactivity: Stable; non-reactive under normal conditions
4. Storage & Handling Attributes
- Storage Conditions: Store in a cool, dry place away from moisture and direct sunlight
- Container Type: Airtight, moisture-proof containers or bags
- Shelf Life: Typically 2–3 years if stored properly
- Special Handling: Avoid dust formation; use dust masks if needed during handling
5. Regulatory & Compliance Attributes
- Pharmacopoeia Standards: Complies with BP, USP, EP specifications
- FDA Status: Generally recognized as safe (GRAS) for pharmaceutical use
- REACH Status: Registered
- Transportation: Not regulated as hazardous
- Waste Disposal: Dispose according to local regulations; non-toxic and biodegradable
6. Environmental & Health Impact
- Ecotoxicity: Low environmental impact; biodegradable polymer
- Persistence: Breaks down naturally in environment
- Bioaccumulation: Not expected
- Carcinogenicity/Mutagenicity: Not classified as hazardous
Biodegradability: Readily biodegradable
SAFETY HANDLING PRECAUTIONS
-
Safety Handling Precautions
Personal Protective Equipment (PPE):
- Dust mask or respirator to avoid inhalation
- Protective gloves and safety glasses recommended
Handling Measures:
- Minimize dust generation
- Use proper ventilation when handling powder
Storage Measures:
- Keep containers tightly sealed to prevent moisture ingress
Hygiene Practices:
- Wash hands after handling
- Avoid eating, drinking, or smoking during handling
First Aid Measures
- Inhalation: Remove to fresh air; seek medical attention if irritation persists
- Skin Contact: Wash with soap and water; unlikely to cause irritation
- Eye Contact: Rinse thoroughly with water; seek medical attention if irritation occurs
- Ingestion: Non-toxic; rinse mouth and seek medical advice if large amounts ingested
Firefighting Measures
- Fire Hazards: Combustible dust; avoid dust cloud formation
- Extinguishing Media: Use water spray, foam, dry chemical, or CO₂
- Special Precautions: Wear dust respirators and protective clothing
Decomposition Products: Carbon oxides and water vapor
Related products
Calcium Propionate
Calcium Propionate is the calcium salt of propionic acid, appearing as a white, crystalline powder or granules with a slightly salty taste and low odor. It is highly soluble in water and used primarily as a food preservative and mold inhibitor. Calcium Propionate inhibits the growth of mold, bacteria, and fungi, making it especially valuable in baked goods, dairy products, and animal feed to extend shelf life and prevent spoilage. It also finds application in pharmaceuticals and cosmetics as a preservative and antimicrobial agent.
Cetomacrogol PEG1000 (Ginonic CSA 20)
Cetomacrogol PEG (Ginonic CSA) is a polyethylene glycol-based nonionic surfactant and emulsifier with an average molecular weight of approximately 1000 Da. It appears as a white to off-white waxy solid or flakes with a neutral odor. This high-quality grade is widely used in cosmetic, pharmaceutical, and personal care formulations due to its excellent emulsifying, solubilizing, and moisturizing properties. Cetomacrogol PEG1000 (Ginonic CSA 20) facilitates stable oil-in-water emulsions, improves product texture and skin feel, and enhances the bioavailability of active ingredients. Its hydrophilic nature and compatibility with a wide range of ingredients make it a versatile additive in creams, lotions, ointments, and topical gels.
Cetrimide Powder
Cetrimide Powder is a high-purity quaternary ammonium compound widely used for its antiseptic, disinfectant, and surfactant properties. It is a cationic surfactant derived from cetyltrimethylammonium bromide and appears as a white to off-white crystalline powder with a slight characteristic odor. Known for its excellent antimicrobial efficacy against bacteria and fungi, cetrimide is frequently incorporated in pharmaceutical, personal care, and industrial formulations. It acts as a bactericidal agent, detergent, and emulsifier, providing effective cleaning and disinfecting action.
Chlorobutanol BP
Chlorobutanol BP (also known as 1,1,1-Trichloro-2-methyl-2-propanol) is a white crystalline solid or powder, with a slight camphor-like odor and a bitter taste. It is a multifunctional preservative, anesthetic, and antimicrobial agent commonly used in pharmaceutical, cosmetic, and personal care products. Chlorobutanol exhibits bacteriostatic and fungistatic properties, making it effective in preventing microbial contamination in aqueous formulations. It also possesses mild local anesthetic effects, frequently used in ophthalmic and injectable preparations as a preservative and stabilizer.
Dipotassium Hydrogen Phosphate
Dipotassium Hydrogen Phosphate (also known as dipotassium phosphate, DKP) is an inorganic salt used widely as a buffering agent, emulsifier, and nutritional supplement in various industries. It is a white, crystalline, highly water-soluble powder with alkaline properties. DKP plays a vital role in food processing, pharmaceuticals, water treatment, and agriculture due to its ability to stabilize pH, improve texture, and supply essential potassium and phosphate ions.
Disodium EDTA
Disodium EDTA (Ethylenediaminetetraacetic acid disodium salt) is a white, odorless, crystalline powder known for its strong chelating properties. With a purity of 99%, it is widely used across numerous industries to bind metal ions, improve stability, and enhance performance in formulations. Disodium EDTA is highly soluble in water, slightly acidic to neutral in solution, and stable under standard storage conditions. Its ability to sequester metal ions like calcium, magnesium, and iron makes it a critical additive in food, pharmaceuticals, cosmetics, water treatment, and industrial applications.
Gelatin Powder 180 Bloom
Gelatin Powder 180 Bloom is a high-quality, partially hydrolyzed collagen protein derived primarily from the skin, bones, and connective tissues of animals such as pigs and cows. The “180 Bloom” rating indicates its gel strength, meaning it forms a firm gel, making it suitable for various industrial, food, pharmaceutical, and cosmetic applications. Gelatin is a natural biopolymer, pale yellow to off-white in color, odorless, and tasteless. It is widely used due to its excellent gelling, film-forming, emulsifying, and stabilizing properties. The powder form offers ease of handling, storage, and precise dosing.
Glycerol Monostearate Flakes
Glycerol Monostearate Flakes is a white to off-white waxy flake form emulsifier composed of 40% monoglycerides of fatty acids, primarily stearic and palmitic acids, combined with other glycerides and esters. Derived mainly from vegetable oils, this food-grade emulsifier is widely utilized in food, cosmetic, pharmaceutical, and industrial sectors for its multifunctional properties. GMS 40% flakes serve as effective emulsifiers, stabilizers, anti-caking agents, and texture enhancers, with excellent compatibility and versatility in formulations requiring semi-solid or solid fats.
