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Povidone PVP25 USP
Povidone PVP25 USP is a synthetic polymer of vinylpyrrolidone with an average molecular weight of approximately 25,000. It is a water-soluble, non-toxic, and biodegradable polymer widely used as a binder, film former, stabilizer, and solubilizing agent in pharmaceutical, cosmetic, and industrial applications. Its excellent adhesive properties and compatibility with a wide range of substances make it essential in tablet formulations, topical products, and adhesives.
Povidone PVP25 USP
Primary Uses
- Pharmaceutical Industry
- Used as a binder in tablet formulations to improve mechanical strength and cohesiveness.
- Acts as a solubilizer and stabilizer in suspensions and solutions.
- Employed in topical ointments and gels as a film former and stabilizer.
- Used in capsule formulations as a binder and disintegrant.
- Cosmetics and Personal Care
- Incorporated in hair sprays, lotions, and creams for film formation and viscosity control.
- Used as a stabilizer and thickening agent in skincare products.
- Industrial Applications
- Utilized as an adhesive component in adhesives and coatings.
- Used in inks and paints as a dispersing and binding agent.
Secondary Uses
- Food Industry
- Occasionally used as a stabilizer or thickener in food processing under regulated conditions.
- Veterinary Medicine
- Applied in veterinary formulations as a binder and stabilizer.
- Textile Industry
- Used in textile printing and finishing for improved adhesion and durability.
1. Basic Identification Attributes
- Chemical Name (IUPAC): Poly(1-vinyl-2-pyrrolidone)
- Common/Trade Name: Povidone PVP25 USP
- CAS Number: 9003-39-8
- HS Code: 3905.90
- Synonyms: PVP K25; Polyvinylpyrrolidone 25,000
2. Physical & Chemical Properties
- Physical State: White to off-white powder
- Color & Odor: Odorless, tasteless
- Solubility: Soluble in water, alcohols; insoluble in ether and hydrocarbons
- Molecular Weight: Approximately 25,000 Da
- Density: ~1.2 g/cm³
- Stability: Stable under normal storage conditions
3. Safety & Hazard Attributes
- GHS Classification: Generally regarded as safe; minimal toxicity
- Toxicity: Low toxicity; non-irritant in typical applications
- Exposure Limits: No established occupational limits; good hygiene recommended
4. Storage & Handling Attributes
- Storage Conditions: Store in a cool, dry place in sealed containers
- Container Type: Plastic bags, drums, or containers
- Shelf Life: Typically 3–5 years if stored properly
- Handling Precautions: Avoid dust formation; use protective masks if needed
5. Regulatory & Compliance Attributes
- Complies with USP (United States Pharmacopeia) standards
- Approved for pharmaceutical and cosmetic use worldwide
6. Environmental & Health Impact
- Biodegradability: Biodegradable polymer
- Ecotoxicity: Low environmental impact
- Bioaccumulation: Not significant
Safety Handling Precautions
- PPE Required: Gloves and dust mask recommended during handling
- Handling Guidelines: Avoid inhalation of dust; use in well-ventilated areas
- Storage Measures: Keep container tightly closed and dry
First Aid Measures
- Inhalation: Move to fresh air if irritation occurs
- Skin Contact: Wash with water if irritation develops
- Eye Contact: Rinse eyes thoroughly with water
- Ingestion: Rinse mouth; seek medical attention if adverse effects occur
Firefighting Measures
- Fire Hazards: Combustible dust may form explosive mixtures in air
- Extinguishing Media: Water spray, foam, dry chemical, or CO₂
- Special Precautions: Avoid dust accumulation and ignition sources
- Hazardous Combustion Products: Carbon oxides, nitrogen oxides
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