Loperamide HCL
Loperamide HCL is a synthetic opioid-receptor agonist used primarily as an antidiarrheal medication. It acts on the µ-opioid receptors in the intestinal wall to decrease gut motility, prolonging transit time and allowing increased absorption of fluids and electrolytes. Loperamide HCL is widely used in pharmaceutical formulations to treat acute and chronic diarrhea, including travelers’ diarrhea and diarrhea associated with inflammatory bowel disease. It is a white to off-white crystalline powder, highly soluble in water and commonly supplied in pharmaceutical grade for oral dosage forms.