Cetomacrogel 1000BP

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Cetomacrogel 1000BP is a high molecular weight polyethylene glycol (PEG) derivative, typically used as a thickening agent, emulsifier, and stabilizer in pharmaceutical and cosmetic formulations. It appears as a white to off-white, waxy solid or flakes with a neutral odor. Known for its excellent water solubility and compatibility with various ingredients, Cetomacrogel 1000BP enhances texture, viscosity, and stability in creams, ointments, and gels. It serves as a hydrophilic vehicle base in topical and oral pharmaceutical preparations and improves product spreadability and skin feel.

Description

Cetomacrogel 1000BP Uses

Primary Uses 

Pharmaceuticals

  • Used as a hydrophilic base and thickener in topical ointments, creams, and gels.

  • Functions as a solubilizer and stabilizer in liquid and semi-solid pharmaceutical formulations.

  • Acts as a binder and matrix former in oral and topical drug delivery systems.

  • Employed in suppository bases due to its water-soluble and melting properties.

Cosmetics & Personal Care

  • Used in moisturizing creams, lotions, and gels to enhance viscosity and texture.

  • Acts as an emulsifier and stabilizer in oil-in-water emulsions.

  • Provides a smooth, non-greasy skin feel and improves product spreadability.

 

Secondary Uses

Industrial Applications

  • Utilized in lubricant formulations to improve consistency and performance.

  • Applied in textile and paper industries as a thickening and binding agent.

Food Industry

  • Occasionally used as a processing aid or carrier for flavor and colorants under regulatory approvals.
PRODUCT KEY FEATURES
  1. Basic Identification Attributes
  • Chemical Name (IUPAC): Polyethylene glycol (PEG) with average molecular weight ~1000 Da

  • Common/Trade Name: Cetomacrogel 1000BP

  • CAS Number: 25322-68-3 (for PEG 1000)

  • HS Code: 3907.99.00

  • Molecular Formula: (C2H4O)nH2O, where n corresponds to molecular weight approx. 1000 Da

  • Synonyms:

    • PEG 1000

    • Polyethylene glycol 1000

    • Macrogol 1000

 

  1. Physical & Chemical Properties
  • Physical State: White to off-white solid flakes or waxy granules

  • Color & Odor: White to pale; odorless or faintly characteristic odor

  • Melting Point: 37–40°C (softens and melts)

  • Boiling Point: Not applicable (decomposes on heating)

  • Density: ~1.13 g/cm³ at 20°C

  • Solubility:

    • Completely soluble in water

    • Soluble in alcohols and glycols

    • Insoluble in hydrocarbons and oils

  • Stability: Stable under normal storage conditions; hygroscopic

 

  1. Safety & Hazard Attributes
  • Hazard Class (GHS): Not classified as hazardous

  • NFPA Ratings:

    • Health: 0

    • Flammability: 1

    • Reactivity: 0

  • Exposure Limits: No established limits; generally considered safe

  • Toxicity: Low toxicity; widely used in pharmaceuticals and cosmetics safely

  • Irritation Potential: Non-irritating to skin and eyes under normal use

 

  1. Storage & Handling Attributes
  • Storage Conditions: Store in a cool, dry place, tightly closed to prevent moisture uptake

  • Container Type: Supplied in sealed bags, drums, or pails

  • Shelf Life: Typically 3 years if stored properly

  • Special Handling: Avoid dust generation; use PPE as needed

 

  1. Regulatory & Compliance Attributes
  • Pharmacopoeial Status: Complies with BP (British Pharmacopoeia) standards

  • Cosmetic Regulatory Status: Approved for use in cosmetic formulations globally

  • REACH Status: Registered

  • Transportation: Not regulated as hazardous material

  • Waste Disposal: Dispose according to local regulations; biodegradable

 

  1. Environmental & Health Impact
  • Ecotoxicity: Low; biodegradable and environmentally friendly

  • Persistence: Readily biodegradable in the environment

  • Bioaccumulation: Not expected to bioaccumulate

  • Carcinogenicity/Mutagenicity: Not classified as carcinogenic or mutagenic

Biodegradability: Readily biodegradable

SAFETY HANDLING PRECAUTIONS
  • Safety Handling Precautions

  • PPE: Use gloves and dust mask if handling large quantities or powders

  • Handling: Avoid inhalation of dust; ensure adequate ventilation

  • Storage: Keep container sealed and protected from moisture

  • Hygiene: Wash hands after handling; do not eat or drink in handling area

 

First Aid Measures

  • Inhalation: Move to fresh air if dust inhaled; seek medical attention if symptoms persist

  • Skin Contact: Wash skin with water; no expected adverse effects

  • Eye Contact: Rinse with plenty of water; seek medical attention if irritation occurs

  • Ingestion: Non-toxic; rinse mouth and seek medical advice if large amounts ingested

 

Firefighting Measures

  • Fire Hazards: Combustible at high temperatures

  • Extinguishing Media: Water spray, foam, dry chemical, COâ‚‚

  • Special Precautions: Firefighters should use protective equipment

Decomposition Products: May produce carbon monoxide, carbon dioxide, and other toxic fumes