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Cetomacrogel 1000BP
Cetomacrogel 1000BP is a high molecular weight polyethylene glycol (PEG) derivative, typically used as a thickening agent, emulsifier, and stabilizer in pharmaceutical and cosmetic formulations. It appears as a white to off-white, waxy solid or flakes with a neutral odor. Known for its excellent water solubility and compatibility with various ingredients, Cetomacrogel 1000BP enhances texture, viscosity, and stability in creams, ointments, and gels. It serves as a hydrophilic vehicle base in topical and oral pharmaceutical preparations and improves product spreadability and skin feel.
Cetomacrogel 1000BP
Primary UsesÂ
- Pharmaceuticals
- Used as a hydrophilic base and thickener in topical ointments, creams, and gels.
- Functions as a solubilizer and stabilizer in liquid and semi-solid pharmaceutical formulations.
- Acts as a binder and matrix former in oral and topical drug delivery systems.
- Employed in suppository bases due to its water-soluble and melting properties.
- Cosmetics & Personal Care
- Used in moisturizing creams, lotions, and gels to enhance viscosity and texture.
- Acts as an emulsifier and stabilizer in oil-in-water emulsions.
- Provides a smooth, non-greasy skin feel and improves product spreadability.
Secondary Uses
- Industrial Applications
- Utilized in lubricant formulations to improve consistency and performance.
- Applied in textile and paper industries as a thickening and binding agent.
- Food Industry
- Occasionally used as a processing aid or carrier for flavor and colorants under regulatory approvals.
1. Basic Identification Attributes
- Chemical Name (IUPAC): Polyethylene glycol (PEG) with average molecular weight ~1000 Da
- Common/Trade Name: Cetomacrogel 1000BP
- CAS Number: 25322-68-3 (for PEG 1000)
- HS Code: 3907.99.00
- Molecular Formula: (C2H4O)nH2O, where n corresponds to molecular weight approx. 1000 Da
- Synonyms:
- PEG 1000
- Polyethylene glycol 1000
- Macrogol 1000
2. Physical & Chemical Properties
- Physical State: White to off-white solid flakes or waxy granules
- Color & Odor: White to pale; odorless or faintly characteristic odor
- Melting Point: 37–40°C (softens and melts)
- Boiling Point: Not applicable (decomposes on heating)
- Density: ~1.13 g/cm³ at 20°C
- Solubility:
- Completely soluble in water
- Soluble in alcohols and glycols
- Insoluble in hydrocarbons and oils
- Stability: Stable under normal storage conditions; hygroscopic
3. Safety & Hazard Attributes
- Hazard Class (GHS): Not classified as hazardous
- NFPA Ratings:
- Health: 0
- Flammability: 1
- Reactivity: 0
- Exposure Limits: No established limits; generally considered safe
- Toxicity: Low toxicity; widely used in pharmaceuticals and cosmetics safely
- Irritation Potential: Non-irritating to skin and eyes under normal use
4. Storage & Handling Attributes
- Storage Conditions: Store in a cool, dry place, tightly closed to prevent moisture uptake
- Container Type: Supplied in sealed bags, drums, or pails
- Shelf Life: Typically 3 years if stored properly
- Special Handling: Avoid dust generation; use PPE as needed
5. Regulatory & Compliance Attributes
- Pharmacopoeial Status: Complies with BP (British Pharmacopoeia) standards
- Cosmetic Regulatory Status: Approved for use in cosmetic formulations globally
- REACH Status: Registered
- Transportation: Not regulated as hazardous material
- Waste Disposal: Dispose according to local regulations; biodegradable
6. Environmental & Health Impact
- Ecotoxicity: Low; biodegradable and environmentally friendly
- Persistence: Readily biodegradable in the environment
- Bioaccumulation: Not expected to bioaccumulate
- Carcinogenicity/Mutagenicity: Not classified as carcinogenic or mutagenic
- Biodegradability: Readily biodegradable
Safety Handling Precautions
- PPE: Use gloves and dust mask if handling large quantities or powders
- Handling: Avoid inhalation of dust; ensure adequate ventilation
- Storage: Keep container sealed and protected from moisture
- Hygiene: Wash hands after handling; do not eat or drink in handling area
First Aid Measures
- Inhalation: Move to fresh air if dust inhaled; seek medical attention if symptoms persist
- Skin Contact: Wash skin with water; no expected adverse effects
- Eye Contact: Rinse with plenty of water; seek medical attention if irritation occurs
- Ingestion: Non-toxic; rinse mouth and seek medical advice if large amounts ingested
Firefighting Measures
- Fire Hazards: Combustible at high temperatures
- Extinguishing Media: Water spray, foam, dry chemical, COâ‚‚
- Special Precautions: Firefighters should use protective equipment
- Decomposition Products: May produce carbon monoxide, carbon dioxide, and other toxic fumes
Related products
Cetomacrogol PEG1000 (Ginonic CSA 20)
Cetomacrogol PEG (Ginonic CSA) is a polyethylene glycol-based nonionic surfactant and emulsifier with an average molecular weight of approximately 1000 Da. It appears as a white to off-white waxy solid or flakes with a neutral odor. This high-quality grade is widely used in cosmetic, pharmaceutical, and personal care formulations due to its excellent emulsifying, solubilizing, and moisturizing properties. Cetomacrogol PEG1000 (Ginonic CSA 20) facilitates stable oil-in-water emulsions, improves product texture and skin feel, and enhances the bioavailability of active ingredients. Its hydrophilic nature and compatibility with a wide range of ingredients make it a versatile additive in creams, lotions, ointments, and topical gels.
Emulsifying Wax Anionic
Emulsifying Wax Anionic is a versatile surfactant blend composed primarily of fatty alcohols (such as cetyl or stearyl alcohol) and anionic surfactants like sodium lauryl sulfate. It is designed to stabilize oil-in-water (O/W) emulsions by reducing interfacial tension between water and oil phases. It appears as white to off-white solid flakes or pellets, with a mild fatty odor and is dispersible in water with agitation and mild heat. Known for its excellent emulsification, cleansing, and thickening properties, this emulsifying wax is widely used in cosmetics, pharmaceuticals, household cleaners, and industrial applications.
Galaxy MW 257( Lutensol A07)
Galaxy MW 257( Lutensol A07), also known commercially as Lutensol A07, is a nonionic surfactant belonging to the class of ethoxylated alcohols. It is synthesized by ethoxylation of C7 fatty alcohols, resulting in a hydrophilic-lipophilic balance (HLB) suitable for versatile applications in detergency, emulsification, wetting, and dispersing. This liquid surfactant is valued for its excellent surface-active properties, biodegradability, low toxicity, and compatibility with other formulation ingredients. It is widely used in industrial, household, agricultural, and personal care products to improve formulation stability and performance.
Oleic Acid
Oleic Acid is a naturally occurring monounsaturated fatty acid commonly derived from vegetable oils such as olive, sunflower, and canola oils. This oily liquid is widely used in the chemical, pharmaceutical, cosmetic, and food industries due to its excellent emollient, surfactant, and stabilizing properties. Oleic Acid 75% is a key raw material in manufacturing soaps, detergents, lubricants, and personal care products. Its amphiphilic nature makes it an effective emulsifier and penetration enhancer.
Polyglycerol-10-Laurate
Polyglycerol-10-Laurate is a non-ionic, biodegradable surfactant and emulsifier derived from natural lauric acid and polyglycerol (with ten glycerol units). It is known for its excellent emulsifying, dispersing, and solubilizing properties, especially in oil-in-water systems. Commonly used in cosmetics, food, pharmaceuticals, and personal care products, it is valued for being mild, non-toxic, and suitable for sensitive applications, including baby care and oral care.
Polyglyceryl
Polyglyceryl refers to a family of non-ionic surfactants and emulsifiers made by the polymerization of glycerol units. Depending on the number of glycerol units (e.g., Polyglyceryl-2, -3, -6, -10) and fatty acid esterification (e.g., laurate, oleate, stearate), they offer different emulsifying and solubilizing properties. These compounds are biodegradable, mild, and skin-friendly, making them ideal for use in cosmetics, food, pharmaceuticals, and personal care products. Polyglyceryl esters are often chosen in natural and organic product formulations due to their origin and non-toxic profile.
Polysorbates
Polysorbates are a class of nonionic surfactants derived from sorbitol and fatty acids, commonly used as emulsifiers, solubilizers, and dispersing agents in a wide range of industries. They improve the mixing of oil and water phases, stabilize emulsions, and enhance the texture and consistency of formulations. Polysorbates are widely used in pharmaceuticals, cosmetics, food products, and industrial applications due to their biocompatibility, low toxicity, and effectiveness at low concentrations.
Turkey Red Oil (Sulphated Castor Oil)
Turkey Red Oil (Sulphated Castor Oil), also known as Sulphated Castor Oil, is a water-soluble derivative of castor oil produced by the sulfonation of castor oil. It appears as a viscous, amber to dark brown liquid with excellent emulsifying, detergent, and wetting properties. Turkey Red Oil is widely used as a natural surfactant and emulsifier in various industrial and personal care applications. It is known for its biodegradability, mildness, and ability to stabilize oil-in-water emulsions. Traditionally used in textile processing as a softener and lubricant, it now finds broad usage in cosmetics, detergents, leather processing, and cleaning products due to its unique functional attributes.
