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Polysorbates
Polysorbates are a class of nonionic surfactants derived from sorbitol and fatty acids, commonly used as emulsifiers, solubilizers, and dispersing agents in a wide range of industries. They improve the mixing of oil and water phases, stabilize emulsions, and enhance the texture and consistency of formulations. Polysorbates are widely used in pharmaceuticals, cosmetics, food products, and industrial applications due to their biocompatibility, low toxicity, and effectiveness at low concentrations.
Polysorbates
Primary Uses
- Pharmaceutical Industry
- Used as emulsifiers and solubilizing agents in oral, topical, and injectable drug formulations.
- Helps to stabilize suspensions and emulsions.
- Improves bioavailability of poorly soluble drugs.
- Food Industry
- Acts as emulsifiers in baked goods, ice creams, salad dressings, and beverages.
- Enhances texture, shelf life, and consistency of food products.
- Used in fat-based spreads and confectionery to improve mixing and prevent separation.
- Cosmetics and Personal Care
- Emulsifies oils and water in creams, lotions, shampoos, and conditioners.
- Enhances product texture, stability, and skin feel.
- Helps disperse fragrances and active ingredients evenly.
- Industrial Applications
- Used in textile processing, detergents, and paints as emulsifiers and dispersants.
- Facilitates the formulation of emulsions and suspensions in various manufacturing processes.
Secondary Uses
- Agriculture
- Used as adjuvants in pesticide formulations to improve spreading and adhesion.
- Biomedical Research
- Employed as stabilizers in vaccine formulations and cell culture media.
- Lubricants and Coatings
- Improves miscibility and stability in lubricant and coating formulations.
- Improves miscibility and stability in lubricant and coating formulations.
1. Basic Identification Attributes
- Chemical Name (IUPAC): Polyoxyethylene sorbitan esters (varies by fatty acid chain)
- Common/Trade Name: Polysorbate 20, Polysorbate 40, Polysorbate 60, Polysorbate 80 (most common types)
- CAS Number: Varies (e.g., Polysorbate 80: 9005-65-6)
- HS Code: 3402.19.00 (Surface-active agents)
- Synonyms: Tween (common trade name), Polyoxyethylene sorbitan fatty acid esters
2. Physical & Chemical Properties
- Physical State: Viscous liquid or semi-solid
- Color: Pale yellow to amber
- Odor: Mild, characteristic odor
- pH: Typically 6.0–8.0 in aqueous solution
- Solubility: Soluble in water and alcohol; forms stable emulsions
- HLB (Hydrophilic-Lipophilic Balance): Range from 8.6 to 16.7 depending on type (higher HLB = more hydrophilic)
- Density: Approx. 1.05 g/cm³
3. Safety & Hazard Attributes
- GHS Classification: Generally not classified as hazardous
- Toxicity: Low toxicity; considered safe for food and cosmetic use within regulatory limits
- Irritation Potential: Mild skin and eye irritant at high concentrations
- Flammability: Non-flammable
4. Storage & Handling Attributes
- Storage Conditions: Store in a cool, dry place away from direct sunlight and heat
- Container Type: Supplied in plastic drums, bottles, or bulk containers
- Shelf Life: Typically 2–3 years if stored properly
- Handling Precautions: Avoid inhalation of aerosols and prolonged skin contact
5. Regulatory & Compliance Attributes
- Complies with:
- FDA regulations for food-grade emulsifiers
- Cosmetic ingredient safety standards (e.g., EU Cosmetic Regulation)
- USP/NF monographs for pharmaceutical grades
- REACH and other international chemical safety regulations
- FDA regulations for food-grade emulsifiers
6. Environmental & Health Impact
- Biodegradability: Readily biodegradable
- Ecotoxicity: Low environmental impact when used as directed
- Bioaccumulation: Not expected to bioaccumulate
- Carcinogenicity/Mutagenicity: Not classified as hazardous
Safety Handling Precautions
- PPE Required: Gloves and safety goggles recommended during handling of concentrated material
- Handling Guidelines: Use in well-ventilated areas; avoid inhalation of mist or aerosols
- Storage Measures: Keep containers tightly closed; avoid contamination
First Aid Measures
- Inhalation: Move to fresh air if irritation occurs
- Skin Contact: Wash with soap and water; seek medical advice if irritation persists
- Eye Contact: Rinse thoroughly with water for at least 15 minutes; seek medical attention if irritation continues
- Ingestion: Rinse mouth; seek medical advice if discomfort or symptoms develop
Firefighting Measures
- Fire Hazards: Not flammable but can burn under fire conditions
- Extinguishing Media: Water spray, foam, dry chemical, or CO₂
- Special Precautions: Use standard protective equipment
- Hazardous Combustion Products: May produce carbon oxides and other toxic fumes during combustion
Related products
Booster Emulsifier
Booster Emulsifier is a specialized surfactant-based additive formulated to enhance the stability, texture, and uniformity of emulsions in food, cosmetic, and pharmaceutical formulations. It acts by reducing surface tension between immiscible liquids such as oil and water, facilitating the formation of stable, homogeneous emulsions. Booster Emulsifier is valued for its ability to improve product appearance, extend shelf life, and enhance sensory properties such as mouthfeel and creaminess. It is typically available as a liquid or powder and compatible with a wide range of ingredients.
Carboxymethyl Cellulose Food Grade
Carboxymethyl Cellulose Food Grade is a water-soluble cellulose derivative produced by the etherification of cellulose with monochloroacetic acid. It appears as a fine, white to off-white powder with excellent thickening, stabilizing, and water retention properties. Designed specifically for food applications, this grade complies with food safety regulations and is widely used as a texture modifier, stabilizer, and emulsifier in a variety of processed foods. It enhances product consistency, extends shelf life, and improves moisture retention without altering taste or odor. Being non-toxic, biodegradable, and non-caloric, it is considered safe for human consumption and is approved as a food additive in many countries.
Centrimonium Chloride Solution
Centrimonium Chloride Solution (also known as Cetyltrimethylammonium Chloride), with the chemical formula C₁₉H₄₂ClN, is a quaternary ammonium compound presented here as a 30% aqueous solution. It is a cationic surfactant widely used as an antistatic agent, conditioner, and emulsifier in personal care and industrial applications. This 25kg packaged solution is highly soluble and stable, providing excellent conditioning and antimicrobial properties in hair care formulations, fabric softeners, and disinfectants.
Ceteareth 20 Ginonic
Ceteareth 20 Ginonic CSA 20 is a nonionic surfactant and emulsifier derived from the ethoxylation of cetearyl alcohol, incorporating approximately 20 ethylene oxide units per molecule. It appears as a white to off-white waxy solid or viscous liquid, depending on temperature and formulation. This emulsifier is widely used in cosmetic, pharmaceutical, and industrial formulations for its excellent ability to stabilize oil-in-water emulsions, improve texture, and enhance the sensory properties of finished products. Its high hydrophilic-lipophilic balance (HLB) makes it especially effective in forming stable emulsions and solubilizing lipophilic ingredients in aqueous phases. Ceteareth 20 is valued for its mildness, broad compatibility, and multifunctional performance.
Emulsifying Wax Non ionic
Emulsifying Wax Non ionic is a self-emulsifying, non-ionic wax blend composed primarily of fatty alcohols (typically cetostearyl alcohol or stearyl alcohol) and non-ionic surfactants like polyethylene glycol (PEG) derivatives. It is used to stabilize oil-in-water (O/W) emulsions without relying on ionic charges, making it highly compatible with a wide range of ingredients, including both cationic and anionic components. This wax is commonly found in white, odorless solid flakes or pellets and is dispersible in hot water to form smooth, stable emulsions. It is widely used in cosmetic, pharmaceutical, and industrial applications where gentle emulsification, stability, and broad pH compatibility are needed.
Galaxy MW 257( Lutensol A07)
Galaxy MW 257( Lutensol A07), also known commercially as Lutensol A07, is a nonionic surfactant belonging to the class of ethoxylated alcohols. It is synthesized by ethoxylation of C7 fatty alcohols, resulting in a hydrophilic-lipophilic balance (HLB) suitable for versatile applications in detergency, emulsification, wetting, and dispersing. This liquid surfactant is valued for its excellent surface-active properties, biodegradability, low toxicity, and compatibility with other formulation ingredients. It is widely used in industrial, household, agricultural, and personal care products to improve formulation stability and performance.
Galsilk 700( polyquartenum 7)
Galsilk 700( polyquartenum 7) is a water-soluble cationic polymer known chemically as Polyquaternium-7. It is widely used as a conditioning agent in personal care and cosmetic formulations, prized for its excellent substantivity to hair and skin, providing softness, smoothness, and antistatic effects. This polymer is typically supplied as a clear to slightly hazy viscous liquid or gel. It is compatible with a broad range of surfactants and ingredients, enhancing the sensory profile of shampoos, conditioners, styling products, and skincare formulations. Galsilk 700 is also valued for its film-forming properties and ability to improve product stability.
Oleic Acid
Oleic Acid is a naturally occurring monounsaturated fatty acid commonly derived from vegetable oils such as olive, sunflower, and canola oils. This oily liquid is widely used in the chemical, pharmaceutical, cosmetic, and food industries due to its excellent emollient, surfactant, and stabilizing properties. Oleic Acid 75% is a key raw material in manufacturing soaps, detergents, lubricants, and personal care products. Its amphiphilic nature makes it an effective emulsifier and penetration enhancer.
