Cetomacrogol PEG1000 (Ginonic CSA 20)

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Cetomacrogol PEG (Ginonic CSA) is a polyethylene glycol-based nonionic surfactant and emulsifier with an average molecular weight of approximately 1000 Da. It appears as a white to off-white waxy solid or flakes with a neutral odor. This high-quality grade is widely used in cosmetic, pharmaceutical, and personal care formulations due to its excellent emulsifying, solubilizing, and moisturizing properties. Cetomacrogol PEG1000 (Ginonic CSA 20) facilitates stable oil-in-water emulsions, improves product texture and skin feel, and enhances the bioavailability of active ingredients. Its hydrophilic nature and compatibility with a wide range of ingredients make it a versatile additive in creams, lotions, ointments, and topical gels.

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Categories: Emollients, Excipients, Surfactants(cosmetic) Tags: Cetomacrogol PEG, Cosmetic emulsions, Emulsifying wax, Non-ionic emulsifier, Pharmaceutical topical preparations, White waxy solid

Description

Table of Contents

Cetomacrogol PEG1000 (Ginonic CSA 20)

Primary Uses

Cosmetics & Personal Care

Functions as a nonionic emulsifier and solubilizer in creams, lotions, and moisturizing gels.
Provides skin conditioning and moisturizing effects by forming a hydrophilic film on the skin.
Enhances texture, spreadability, and stability of oil-in-water formulations.
Used in cleansing products to improve foaming and mildness.

Pharmaceuticals

Acts as an emulsifying agent and solubilizer in topical and oral pharmaceutical formulations.
Serves as a base for ointments, creams, and suppositories, enhancing the delivery of active ingredients.
Improves texture and viscosity in pharmaceutical creams and gels.

Secondary Uses

Industrial Applications

Used in lubricant formulations as a stabilizer and viscosity modifier.
Employed in textile and paper industries as a wetting and dispersing agent.

Food Industry

Occasionally used as a processing aid or carrier in flavor encapsulation under regulatory compliance.

KEY PRODUCT FEATURES

1. Basic Identification Attributes

Chemical Name (IUPAC): Polyethylene glycol 1000 (PEG 1000)
Common/Trade Name: Cetomacrogol PEG1000 (Ginonic CSA 20)
CAS Number: 25322-68-3
HS Code: 3907.99.00
Molecular Formula: (C2H4O)nH2O, where n corresponds to an average molecular weight of ~1000 Da
Synonyms:
- PEG 1000
- Polyethylene glycol 1000
- Macrogol 1000

2. Physical & Chemical Properties

Physical State: White to off-white waxy solid or flakes
Color & Odor: White to pale; odorless or faintly characteristic odor
Melting Point: Approximately 37–40°C (softens and melts)
Boiling Point: Decomposes before boiling
Density: ~1.13 g/cm³ at 20°C
Solubility:
- Soluble in water, alcohols, and glycols
- Insoluble in hydrocarbons and oils
Stability: Stable under normal conditions; hygroscopic

3. Safety & Hazard Attributes

Hazard Class (GHS): Not classified as hazardous
NFPA Ratings:
- Health: 0
- Flammability: 1
- Reactivity: 0
Exposure Limits: No specific limits; generally considered safe for intended uses
Toxicity: Low toxicity; widely accepted for use in cosmetics and pharmaceuticals
Irritation Potential: Minimal; generally non-irritating to skin and eyes

4. Storage & Handling Attributes

Storage Conditions: Store in a cool, dry, and well-ventilated area away from moisture and heat
Container Type: Sealed bags, drums, or pails with moisture-resistant liners
Shelf Life: Typically 3 years if stored correctly
Special Handling: Avoid dust formation; use PPE as appropriate

5. Regulatory & Compliance Attributes

Cosmetic Regulatory Status: Approved globally for use in cosmetics and personal care products
Pharmacopoeial Status: Complies with pharmacopoeial standards where applicable
REACH Status: Registered
Transportation: Not regulated as hazardous material
Waste Disposal: Dispose in compliance with local and national regulations; biodegradable

6. Environmental & Health Impact

Ecotoxicity: Low; biodegradable and environmentally benign
Persistence: Biodegradable under aerobic conditions
Bioaccumulation: Not expected to bioaccumulate
Carcinogenicity/Mutagenicity: No known carcinogenic or mutagenic effects
Biodegradability: Readily biodegradable

SAFETY HANDLING PRECAUTIONS

Safety Handling Precautions

PPE: Use gloves, protective eyewear, and dust masks when handling in powder form
Handling: Ensure adequate ventilation; avoid inhalation of dust or vapors
Storage: Keep containers tightly closed to prevent moisture ingress
Hygiene: Wash hands after handling; avoid ingestion and contact with eyes

First Aid Measures

Inhalation: Move to fresh air if dust inhaled; seek medical attention if respiratory symptoms develop
Skin Contact: Wash thoroughly with soap and water; generally non-irritating
Eye Contact: Rinse immediately with water for at least 15 minutes; seek medical advice if irritation persists
Ingestion: Non-toxic in small amounts; seek medical advice if large quantities are ingested

Firefighting Measures

Fire Hazards: Combustible at elevated temperatures
Extinguishing Media: Water spray, foam, dry chemical, or carbon dioxide
Special Precautions: Firefighters should wear full protective equipment and self-contained breathing apparatus
Decomposition Products: May release carbon monoxide, carbon dioxide, and other hazardous fumes when burned