Cetrimide Powder

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Cetrimide Powder is a high-purity quaternary ammonium compound widely used for its antiseptic, disinfectant, and surfactant properties. It is a cationic surfactant derived from cetyltrimethylammonium bromide and appears as a white to off-white crystalline powder with a slight characteristic odor. Known for its excellent antimicrobial efficacy against bacteria and fungi, cetrimide is frequently incorporated in pharmaceutical, personal care, and industrial formulations. It acts as a bactericidal agent, detergent, and emulsifier, providing effective cleaning and disinfecting action.

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Category: Antiseptics and Disinfectants Tags: Antiseptic agent, Cetrimide powder, Cosmetic preservative, Disinfectants and sanitizers, First aid creams and solutions, Pharmaceutical antiseptics, White to off-white powder

Description

Table of Contents

Cetrimide Powder

Primary Uses

Pharmaceuticals & Medical

Used as an antiseptic and disinfectant in wound cleaning solutions, surgical scrubs, and topical antiseptic creams and ointments.
Incorporated in medicated shampoos and washes for treatment of dandruff and seborrheic dermatitis due to antimicrobial action.
Acts as a surfactant and emulsifier in pharmaceutical formulations to enhance consistency and stability.

Personal Care & Cosmetics

Utilized in antiseptic creams, lotions, and skin cleansers.
Functions as a foaming agent and cleansing surfactant in shampoos and body washes.
Used in oral care products like mouthwashes for its antimicrobial properties.

Industrial & Household

Employed in disinfectant solutions and surface cleaners for hospitals and households.
Used in water treatment processes as a biocide to control microbial growth.

Secondary Uses

Laboratory & Research

Used as a surfactant in biochemical and microbiological applications.
Employed in DNA extraction protocols and as a detergent in molecular biology.

Textile & Leather Processing

Applied as a wetting and antiseptic agent in textile dyeing and leather treatment processes.

KEY PRODUCT FEATURES

1. Basic Identification Attributes

Chemical Name (IUPAC): N,N,N-trimethyl-1-hexadecylammonium bromide (major component)
Common/Trade Name: Cetrimide Powder 98%
CAS Number: 61789-75-3
HS Code: 2923.29.00
Molecular Formula: C19H42BrN
Synonyms:
- Cetyltrimethylammonium bromide
- Hexadecyltrimethylammonium bromide
- Antiseptic quaternary ammonium compound

2. Physical & Chemical Properties

Physical State: White to off-white crystalline powder
Color & Odor: White; slight characteristic ammonium odor
Melting Point: 55–60°C (decomposes)
Boiling Point: Decomposes before boiling
Density: ~1.01 g/cm³
Solubility:
- Soluble in water (forms clear solutions)
- Soluble in alcohols and acetone
- Insoluble in hydrocarbons
pH (1% aqueous solution): ~5.5–7.0
Stability: Stable under recommended storage conditions; hygroscopic

3. Safety & Hazard Attributes

Hazard Class (GHS): Harmful if swallowed; causes skin and eye irritation
NFPA Ratings:
- Health: 2
- Flammability: 0
- Reactivity: 0
Exposure Limits: No specific exposure limit established; avoid inhalation and skin contact
Toxicity: Moderately toxic; potential irritant to mucous membranes and skin
Reactivity: Stable; avoid mixing with anionic surfactants or oxidizers

4. Storage & Handling Attributes

Storage Conditions: Store in a cool, dry, well-ventilated place away from incompatible materials
Container Type: Sealed polyethylene or glass containers recommended
Shelf Life: 2-3 years if stored properly
Special Handling: Use personal protective equipment (PPE); avoid dust formation and inhalation

5. Regulatory & Compliance Attributes

Pharmacopoeial Status: Listed in BP and USP as antiseptic grade
Cosmetic Regulatory Status: Approved for use as preservative and antiseptic ingredient globally
REACH Status: Registered
Transportation: Not classified as hazardous for transport if packaged properly
Waste Disposal: Dispose according to local environmental regulations

6. Environmental & Health Impact

Ecotoxicity: Toxic to aquatic organisms; avoid release into waterways
Persistence: Moderately persistent in the environment
Bioaccumulation: Potential for bioaccumulation; handle waste responsibly
Carcinogenicity/Mutagenicity: No evidence of carcinogenic or mutagenic effects at recommended use levels
Biodegradability: Partial biodegradability; depends on environmental conditions

SAFETY HANDLING PRECAUTIONS

Safety Handling Precautions

PPE: Gloves, protective goggles, dust mask or respirator if handling powder in bulk
Handling: Avoid dust generation; use in well-ventilated areas
Storage: Keep container tightly closed; store away from acids and anionic surfactants
Hygiene: Wash hands and exposed skin thoroughly after handling

First Aid Measures

Inhalation: Move to fresh air; if breathing is difficult, seek medical attention
Skin Contact: Wash affected area with plenty of soap and water; seek medical advice if irritation persists
Eye Contact: Rinse immediately with plenty of water for at least 15 minutes; seek medical attention
Ingestion: Do not induce vomiting; rinse mouth and seek immediate medical attention

Firefighting Measures

Fire Hazards: Not highly flammable; may burn under fire conditions
Extinguishing Media: Use water spray, foam, dry chemical, or CO₂
Special Precautions: Firefighters should wear full protective clothing and self-contained breathing apparatus
Decomposition Products: May emit toxic fumes including nitrogen oxides, carbon monoxide, and hydrogen bromide on combustion