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Sulfadiazine Base BP
Sulfadiazine Base BP is a broad-spectrum sulfonamide antibiotic used primarily in veterinary and human medicine to treat bacterial infections. It functions by inhibiting bacterial synthesis of folic acid, thereby preventing bacterial growth and proliferation. The British Pharmacopoeia (BP) grade ensures pharmaceutical-grade purity and quality suitable for formulation into tablets, suspensions, and topical preparations.
Sulfadiazine Base BP
Primary Uses
- Human Medicine
- Antibacterial Agent: Used to treat urinary tract infections, respiratory tract infections, and meningitis caused by susceptible bacteria.
- Topical Antimicrobial: Formulated in creams and ointments for treating burns and wound infections.
- Veterinary Medicine
- Animal Antibiotic: Used to treat infections in livestock and pets, including respiratory, urinary, and soft tissue infections.
- Feed Additive: Sometimes included in medicated feed for prophylactic or therapeutic purposes.
Secondary Uses
- Research & Development
- Microbiological Studies: Used in lab research to study bacterial resistance and antibiotic mechanisms.
- Pharmaceutical Formulation: Employed as a model drug in formulation development and bioavailability studies.
- Aquaculture
- Fish Medication: Used to control bacterial diseases in aquaculture under veterinary supervision.
1. Basic Identification Attributes
- Chemical Name (IUPAC): 4-Amino-N-(pyrimidin-2-yl)benzenesulfonamide
- Common/Trade Name: Sulfadiazine Base BP
- CAS Number: 68-35-9
- HS Code: 2941.20.00
- Synonyms: Sulfadiazine, Sulfadiazine base
2. Physical & Chemical Properties
- Physical State: White to off-white crystalline powder
- Color & Odor: White; odorless to faint sulfurous odor
- Melting Point: 254–258 °C (decomposes)
- Solubility: Slightly soluble in water; soluble in alkaline solutions and organic solvents like ethanol
- Density: Approx. 1.65 g/cm³
3. Safety & Hazard Attributes
- GHS Classification: May cause allergic reactions; handle with care
- Toxicity: Moderate; avoid inhalation and prolonged skin contact
- Exposure Limits: No specific occupational exposure limits but good industrial hygiene recommended
4. Storage & Handling Attributes
- Storage Conditions: Store in a cool, dry, well-ventilated place, protected from light and moisture
- Container Type: Sealed HDPE or glass containers
- Shelf Life: 24 months under proper storage conditions
- Handling Precautions: Avoid dust generation; use appropriate PPE including gloves and masks
5. Regulatory & Compliance Attributes
- Conforms to British Pharmacopoeia (BP) standards
- Manufactured under Good Manufacturing Practices (GMP)
- Complies with relevant pharmaceutical regulatory requirements including ICH guidelines
6. Environmental & Health Impact
- Biodegradability: Limited data; sulfonamides generally degrade under aerobic conditions
- Ecotoxicity: Potentially toxic to aquatic organisms; avoid environmental release
- Bioaccumulation: Not significant
Safety Handling Precautions
- PPE Required: Gloves, lab coat, and dust mask recommended
- Handling Guidelines: Use in well-ventilated areas; avoid inhalation and skin contact
- Storage Measures: Keep containers tightly closed and away from incompatible substances
First Aid Measures
- Inhalation: Move to fresh air; seek medical attention if symptoms develop
- Skin Contact: Wash affected area with soap and water; discontinue use if irritation occurs
- Eye Contact: Flush with water for at least 15 minutes; seek medical help if irritation persists
- Ingestion: Rinse mouth; seek medical advice immediately
Firefighting Measures
- Fire Hazards: Combustible solid
- Extinguishing Media: Use water spray, foam, dry chemical, or CO₂ extinguishers
- Hazardous Combustion Products: Carbon oxides, nitrogen oxides, sulfur oxides
Related products
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Ichthammol BP98
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Lidocaine HCL BP
Lidocaine HCL BP is a white crystalline powder or granules that are highly soluble in water. It is a local anesthetic and antiarrhythmic agent widely used in medical and dental fields. Lidocaine HCL BP acts by blocking nerve signal transmission, providing rapid and effective numbing of targeted areas. It conforms to British Pharmacopoeia (BP) standards, ensuring pharmaceutical-grade purity and consistency. It is commonly formulated into injections, topical gels, creams, and patches for pain relief and arrhythmia treatment.
Metronidazole Benzoate BP
Metronidazole Benzoate BP is a benzoate ester derivative of metronidazole, used primarily as an antiprotozoal and antibacterial agent. It is a prodrug that hydrolyzes in the body to release metronidazole, making it more palatable for pediatric and geriatric oral suspensions. It complies with the British Pharmacopoeia (BP) standards for purity and efficacy.
Metronidazole BP
Metronidazole BP is a benzoate ester derivative of metronidazole, used primarily as an antiprotozoal and antibacterial agent. It is a prodrug that hydrolyzes in the body to release metronidazole, making it more palatable for pediatric and geriatric oral suspensions. It complies with the British Pharmacopoeia (BP) standards for purity and efficacy.
Neomycin Sulphate BP Oral
Neomycin Sulphate BP Oral is an aminoglycoside antibiotic derived from Streptomyces fradiae. It is used primarily for treating infections caused by susceptible aerobic gram-negative and some gram-positive bacteria. The oral form is especially utilized for intestinal antisepsis, to reduce bacterial flora before gastrointestinal surgery, or to treat hepatic encephalopathy by decreasing ammonia-producing bacteria in the gut. It is available in powder or tablet form conforming to British Pharmacopoeia (BP) standards, ensuring high purity and efficacy.
Norfloxacin
Norfloxacin is a synthetic broad-spectrum fluoroquinolone antibiotic used primarily to treat bacterial infections. It works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication, transcription, repair, and recombination, leading to bacterial cell death. Norfloxacin is effective against various Gram-negative and some Gram-positive bacteria and is commonly used in urinary tract infections, prostatitis, and gastroenteritis.
Piperazine Citrate BP
Piperazine Citrate BP is a pharmaceutical-grade anthelmintic compound used primarily for the treatment of intestinal worm infections, especially ascariasis (roundworms) and enterobiasis (pinworms). It works by paralyzing the worms, allowing them to be expelled naturally from the body through bowel movements. Piperazine Citrate is included in the British Pharmacopoeia (BP) and is known for its safety, efficacy, and wide use in both human and veterinary medicine.
