Levamisole HCL BP

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Levamisole HCL BP is a white to off-white crystalline powder, soluble in water, with anthelmintic and immunomodulatory properties. It is primarily used as a veterinary antiparasitic agent effective against gastrointestinal nematodes in livestock. Levamisole HCL BP2000 conforms to British Pharmacopoeia standards, ensuring high purity and quality for pharmaceutical and veterinary formulations. Beyond veterinary uses, it is also researched for immunostimulant properties in medical applications.

Description

Levamisole HCL BP

Primary Uses 

  1. Veterinary Medicine

  • Anthelmintic: Treats and controls infections caused by parasitic nematodes (roundworms) in cattle, sheep, goats, pigs, and poultry.
  • Deworming Agent: Used in oral and injectable formulations to improve livestock health and productivity.
  • Immunomodulator: Enhances the immune response in animals, helping resistance against infections.
  1. Pharmaceutical Industry

  • Investigational use as an immunostimulant in adjunct therapy for certain human diseases (e.g., some cancers and autoimmune conditions).
  • Used in combination therapies for improving immune function under clinical research settings.

 

Secondary Uses

  1. Research and Development
  • Employed in biomedical research for studying immune response mechanisms.
  • Utilized in experimental models for parasitic infections and immunomodulation studies.
  1. Agricultural Applications

  • Occasionally used in parasite control protocols in integrated livestock management programs.
PRODUCT KEY FEATURES
  1. Basic Identification Attributes
  • Chemical Name (IUPAC): (S)-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b][1,3]thiazole hydrochloride
  • Common/Trade Name: Levamisole HCL BP2000
  • CAS Number: 14769-73-4
  • HS Code: 2933.39.00
  • Synonyms: Levamisole Hydrochloride; Levamisole HCl; Anthelmintic Levamisole
  1. Physical & Chemical Properties
  • Physical State: Crystalline powder
  • Color & Odor: White to off-white; odorless
  • Solubility: Soluble in water and dilute acids
  • Melting Point: Approximately 225–230 °C (decomposes)

 

  1. Safety & Hazard Attributes
  • GHS Classification: Harmful if swallowed; may cause skin and respiratory sensitization
  • Toxicity: Moderate toxicity; overdose can cause neurotoxicity and other adverse effects
  • Exposure Limits: No established occupational exposure limits; handle with care

 

  1. Storage & Handling Attributes
  • Storage Conditions: Store in a cool, dry place protected from light and moisture
  • Container Type: Sealed, airtight containers or pharmaceutical-grade packaging
  • Shelf Life: Typically 2–3 years if stored properly
  • Handling Precautions: Use gloves and dust masks to avoid inhalation and skin contact

 

  1. Regulatory & Compliance Attributes
  • Complies with British Pharmacopoeia (BP) standards
  • Approved for veterinary use in many countries under respective regulatory authorities
  • Labeling must include safety and handling information as per pharmaceutical guidelines

 

  1. Environmental & Health Impact
  • Biodegradability: Not readily biodegradable; handle disposal responsibly
  • Ecotoxicity: Potentially toxic to aquatic organisms; avoid environmental release
  • Bioaccumulation: Not expected to bioaccumulate significantly
  • Carcinogenicity/Mutagenicity: Not classified as carcinogenic
SAFETY HANDLING PRECAUTIONS
  1. Safety Handling Precautions
  • PPE Required: Gloves, protective clothing, and dust masks or respirators when handling powder
  • Handling Guidelines: Avoid inhalation and direct contact; work in well-ventilated areas
  • Storage Measures: Keep containers tightly closed and away from incompatible substances

 

  1. First Aid Measures
  • Inhalation: Move to fresh air; seek medical attention if breathing difficulties occur
  • Skin Contact: Wash with soap and water; consult a physician if irritation develops
  • Eye Contact: Rinse thoroughly with water for 15 minutes; seek medical advice if irritation persists
  • Ingestion: Do not induce vomiting; seek immediate medical help

 

  1. Firefighting Measures
  • Fire Hazards: Not highly flammable; may decompose on heating producing toxic fumes
  • Extinguishing Media: Use water spray, foam, dry chemical, or carbon dioxide
  • Special Precautions: Firefighters should wear protective gear and self-contained breathing apparatus
  • Hazardous Combustion Products: May emit sulfur oxides, nitrogen oxides, and hydrochloric acid fumes upon decomposition