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Lidocaine HCL BP
Lidocaine HCL BP is a white crystalline powder or granules that are highly soluble in water. It is a local anesthetic and antiarrhythmic agent widely used in medical and dental fields. Lidocaine HCL BP acts by blocking nerve signal transmission, providing rapid and effective numbing of targeted areas. It conforms to British Pharmacopoeia (BP) standards, ensuring pharmaceutical-grade purity and consistency. It is commonly formulated into injections, topical gels, creams, and patches for pain relief and arrhythmia treatment.
Lidocaine HCL BP
Primary UsesÂ
- Medical and Dental Anesthesia
- Local Anesthetic: Used for numbing skin, mucous membranes, and deeper tissues during minor surgical procedures, dental work, and diagnostic tests.
- Regional Anesthesia: Employed in nerve blocks, epidurals, and spinal anesthesia for surgeries and pain management.
- Topical Anesthesia: Applied in creams, gels, or sprays for superficial pain relief such as sunburn, insect bites, and minor skin irritations.
- Cardiology
- Antiarrhythmic Agent: Administered intravenously to treat ventricular arrhythmias, including ventricular tachycardia and ventricular fibrillation during acute cardiac events.
- Pharmaceutical Formulations
- Component in compounded topical analgesics and patches designed for localized pain relief.
- Used in combination with other agents to enhance efficacy in multi-ingredient preparations.
Secondary Uses
- Veterinary Medicine
- Used as a local anesthetic in animals for minor surgical and dental procedures.
- Cosmetic Procedures
- Utilized to reduce pain during cosmetic interventions such as laser treatments, tattooing, and dermal filler injections.
- Research Applications
- Used experimentally to study nerve function and local anesthetic pharmacodynamics.
1. Basic Identification Attributes
- Chemical Name (IUPAC): 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide hydrochloride
- Common/Trade Name: Lidocaine HCL BP; Lidocaine Hydrochloride
- CAS Number: 73-78-9
- HS Code: 2941.00.00
- Synonyms: Lignocaine Hydrochloride; Xylocaine Hydrochloride; Lidocaine HCl
2. Physical & Chemical Properties
- Physical State: Crystalline powder
- Color & Odor: White to off-white; odorless to faint aromatic odor
- Solubility: Freely soluble in water; slightly soluble in alcohol and chloroform
- Melting Point: 68–72 °C
3. Safety & Hazard Attributes
- GHS Classification: Harmful if swallowed; causes skin and eye irritation; may cause respiratory irritation
- Toxicity: Moderate toxicity; overdose can cause CNS and cardiovascular effects
- Exposure Limits: No specific occupational limits, but handle with care
4. Storage & Handling Attributes
- Storage Conditions: Store in a cool, dry place, protected from light and moisture
- Container Type: Sealed pharmaceutical-grade containers
- Shelf Life: Typically 2–3 years under proper storage
- Handling Precautions: Avoid inhalation and direct contact; use protective equipment
5. Regulatory & Compliance Attributes
- Complies with British Pharmacopoeia (BP) standards
- Approved for human medical use in many countries
- Labeling must comply with pharmaceutical regulatory guidelines
6. Environmental & Health Impact
- Biodegradability: Not readily biodegradable
- Ecotoxicity: Avoid environmental release; potentially harmful to aquatic life
- Bioaccumulation: Not significant
- Carcinogenicity/Mutagenicity: Not classified as carcinogenic
Safety Handling Precautions
- PPE Required: Gloves, safety goggles, and lab coat recommended
- Handling Guidelines: Use in well-ventilated areas; avoid dust and inhalation
- Storage Measures: Keep containers tightly closed and away from incompatible substances
First Aid Measures
- Inhalation: Move to fresh air; seek medical attention if symptoms develop
- Skin Contact: Wash with soap and water; seek medical advice if irritation occurs
- Eye Contact: Rinse thoroughly with water for at least 15 minutes; seek medical help if irritation persists
- Ingestion: Do not induce vomiting; seek immediate medical attention
Firefighting Measures
- Fire Hazards: Combustible; emits toxic fumes upon burning
- Extinguishing Media: Use water spray, foam, dry chemical, or carbon dioxide
- Special Precautions: Wear full protective gear and self-contained breathing apparatus if involved in fire
- Hazardous Combustion Products: Carbon monoxide, nitrogen oxides, and other toxic gases
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