Awaiting product image
Click to enlarge
Placeholder
Povidone Iodine BP
Back to products
Placeholder
Magadi Soda Ash
PHARMACEUTICAL GRADE USP GRADE

Nystatin EP5

Whatsapp Order

Product Description

Nystatin EP5 is a polyene antifungal antibiotic used to treat fungal infections caused primarily by Candida species. It acts by binding to ergosterol in fungal cell membranes, creating pores that lead to cell leakage and death. Nystatin EP5 is widely used in pharmaceutical formulations for topical, oral, and mucosal candidiasis treatment. It is non-absorbable from the gastrointestinal tract, making it effective for treating infections in the mouth, throat, and intestines.

 

Add to compare
Add to wishlist
Category: Tags: , , , , ,
Description

Uses

Primary Uses 

  1. Treatment of Candidiasis

    • Effective against cutaneous, mucocutaneous, and oral thrush infections caused by Candida albicans and related species.

    • Used in treating vaginal candidiasis.

  2. Topical Antifungal

    • Incorporated in creams, ointments, powders, and sprays for skin fungal infections.

  3. Oral Suspension and Lozenge

    • Used for oral candidiasis (thrush), especially in immunocompromised patients such as those with HIV/AIDS or undergoing chemotherapy.

  4. Gastrointestinal Fungal Infections

    • Used orally for intestinal candidiasis, since it is not systemically absorbed.

Secondary Uses 

  1. Prophylactic Use

    • Prevention of fungal infections in patients on prolonged antibiotic or corticosteroid therapy.

  2. Veterinary Applications

    • Used in animals for fungal infections of skin and mucous membranes.

  3. Combination Therapies

    • Sometimes combined with other antifungals or antibiotics in complex infections.

  4. Dental Care

    • Formulated in mouthwashes for managing oral fungal infections after dental procedures or in denture wearers.

 

KEY PRODUCT FEATURES

Key Attributes

Basic Identification Attributes

  • Chemical Name (IUPAC): Polyene macrolide antifungal

  • Common/Trade Name: Nystatin EP5

  • CAS Number: 1400-61-9

  • HS Code: 2941.90.99

  • Synonyms: Nystatin, Nystatin antibiotic

Physical & Chemical Properties

  • Physical State: Off-white to yellowish powder or crystalline form

  • Solubility: Sparingly soluble in water, soluble in organic solvents like DMSO

  • Melting Point: Approximately 120–130°C (decomposes)

  • Stability: Stable under recommended storage conditions

Safety & Hazard Attributes

  • GHS Classification: Not classified as hazardous

  • Toxicity: Low systemic toxicity; avoid inhalation of dust and contact with eyes

  • Exposure Limits: No specific occupational limits

Storage & Handling Attributes

  • Storage Conditions: Store in a cool, dry place protected from light and moisture

  • Container Type: Supplied in sealed bottles or containers

  • Shelf Life: Typically 2–3 years when stored properly

  • Handling Precautions: Use dust mask and gloves to avoid inhalation and skin contact

 

Regulatory & Compliance Attributes

  • Complies with European Pharmacopoeia (EP) standards

  • Registered under relevant pharmaceutical regulations and good manufacturing practices (GMP)

 

Environmental & Health Impact

  • Biodegradability: Expected to biodegrade in the environment

  • Ecotoxicity: Low; avoid large releases into aquatic environments

  • Bioaccumulation: Not expected

  • Carcinogenicity/Mutagenicity: Not classified as carcinogenic or mutagenic

SAFETY HANDLING PRECAUTIONS

Safety Handling Precautions

  • PPE Required: Gloves, dust mask, and eye protection recommended

  • Handling Guidelines: Avoid inhaling dust and prolonged skin exposure

  • Storage Measures: Keep container tightly closed and stored in a dry, ventilated area

 

First Aid Measures

  1. Inhalation: Move to fresh air if irritation occurs; seek medical advice if symptoms persist

  2. Skin Contact: Wash with soap and water; discontinue use if irritation develops

  3. Eye Contact: Rinse immediately with plenty of water; seek medical attention if irritation persists

  4. Ingestion: Rinse mouth; seek medical advice if adverse effects occur

 

Firefighting Measures

  • Fire Hazards: Combustible powder

  • Extinguishing Media: Use water spray, foam, dry chemical, or CO₂ extinguishers

  • Special Precautions: Avoid dust formation; wear protective equipment

  • Hazardous Combustion Products: Carbon oxides and nitrogen oxides may be released

 

Related products

Placeholder
Add to compare

Atropine Sulphate

Atropine Sulphate is a crystalline, water-soluble alkaloid salt derived from the belladonna plant (Atropa belladonna) and other Solanaceae family members. It is a tropane alkaloid with potent anticholinergic properties, widely used in medicine for its ability to block muscarinic acetylcholine receptors. Atropine Sulphate is employed in ophthalmology, emergency medicine, and anesthesia for its effects on the eyes, heart, and smooth muscles. It acts by inhibiting parasympathetic nerve impulses, resulting in pupil dilation, increased heart rate, and reduced gland secretions.
Add to wishlist
Read more
Quick view
Placeholder
Add to compare

Colistin Sulphate BP

Colistin Sulphate BP is an antibiotic belonging to the polymyxin class, derived from the bacterium Paenibacillus polymyxa. It is a white to pale yellow powder, soluble in water, and used primarily for its potent bactericidal activity against Gram-negative bacteria, including multidrug-resistant strains. Colistin Sulphate BP is used in both human and veterinary medicine, often as a last-resort treatment for serious infections caused by multidrug-resistant Pseudomonas, Acinetobacter, and Klebsiella species. Due to its efficacy and narrow therapeutic index, its use is carefully monitored. The “BP” denotes compliance with the British Pharmacopoeia standards.
Add to wishlist
Read more
Quick view
Placeholder
Add to compare

Doxycycline Hyclate BP

Doxycycline Hyclate BP is a broad-spectrum, semisynthetic tetracycline-class antibiotic available as the hemihydrate salt form of doxycycline. It is widely used in pharmaceutical formulations due to its high bioavailability, broad antibacterial activity, and favorable pharmacokinetic profile. The compound exhibits bacteriostatic action by inhibiting protein synthesis in susceptible bacteria, making it effective against a wide range of Gram-positive and Gram-negative organisms as well as atypical pathogens. It is typically supplied as a fine, white to off-white crystalline powder soluble in water and suitable for oral and parenteral dosage forms.
Add to wishlist
Read more
Quick view
Placeholder
Add to compare

Enrofloxacin HCl

Enrofloxacin Hydrochloride is a broad-spectrum fluoroquinolone antibiotic used primarily in veterinary medicine. It is the hydrochloride salt of enrofloxacin, offering enhanced solubility and bioavailability. Enrofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, disrupting DNA replication in Gram-negative and Gram-positive organisms as well as some Mycoplasma species. It is available as a white to off-white crystalline powder, used in injectable, oral, and topical formulations designed for livestock, companion animals, and aquatic species.
Add to wishlist
Read more
Quick view
Placeholder
Add to compare

Oxytetracycline HCL BP

Product Description

Oxytetracycline Hydrochloride (HCL) BP is a broad-spectrum tetracycline antibiotic used in human and veterinary medicine. It inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, thus preventing the growth and multiplication of susceptible bacteria. Oxytetracycline HCL is effective against a wide range of Gram-positive and Gram-negative bacteria, as well as some protozoa. It is commonly employed to treat respiratory, urinary, and skin infections, and is also used extensively in veterinary applications to control infectious diseases in livestock and poultry.
Add to wishlist
Read more
Quick view
Placeholder
Add to compare

Piperazine Citrate BP

Piperazine Citrate BP is a pharmaceutical-grade anthelmintic compound used primarily for the treatment of intestinal worm infections, especially ascariasis (roundworms) and enterobiasis (pinworms). It works by paralyzing the worms, allowing them to be expelled naturally from the body through bowel movements. Piperazine Citrate is included in the British Pharmacopoeia (BP) and is known for its safety, efficacy, and wide use in both human and veterinary medicine.
Add to wishlist
Read more
Quick view
Placeholder
Add to compare

Salbutamol Sulphate BP

Salbutamol Sulphate BP is a white to off-white crystalline powder widely used as a bronchodilator in the treatment of asthma, chronic obstructive pulmonary disease (COPD), and other respiratory conditions. It works by relaxing the muscles in the airways, improving airflow and easing breathing. The British Pharmacopoeia (BP) grade ensures high purity and quality suitable for pharmaceutical formulations such as inhalers, tablets, and syrups.
Add to wishlist
Read more
Quick view
Placeholder
Add to compare

Tylosin Tartrate

Tylosin Tartrate is a water-soluble macrolide antibiotic derived from Streptomyces fradiae, primarily used in veterinary medicine. It is the tartrate salt form of tylosin, enhancing its solubility and making it ideal for administration via drinking water or injectable solutions. Tylosin Tartrate is active against a wide range of Gram-positive bacteria and some Gram-negative organisms, as well as Mycoplasma spp. It is particularly effective for treating respiratory, gastrointestinal, and reproductive infections in livestock and poultry.
Add to wishlist
Read more
Quick view