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Polysorbates
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Polysorbates are a class of nonionic surfactants derived from sorbitol and fatty acids, commonly used as emulsifiers, solubilizers, and dispersing agents in a wide range of industries. They improve the mixing of oil and water phases, stabilize emulsions, and enhance the texture and consistency of formulations. Polysorbates are widely used in pharmaceuticals, cosmetics, food products, and industrial applications due to their biocompatibility, low toxicity, and effectiveness at low concentrations.
Description
Polysorbates
Primary Uses
- Pharmaceutical Industry
- Used as emulsifiers and solubilizing agents in oral, topical, and injectable drug formulations.
- Helps to stabilize suspensions and emulsions.
- Improves bioavailability of poorly soluble drugs.
- Food Industry
- Acts as emulsifiers in baked goods, ice creams, salad dressings, and beverages.
- Enhances texture, shelf life, and consistency of food products.
- Used in fat-based spreads and confectionery to improve mixing and prevent separation.
- Cosmetics and Personal Care
- Emulsifies oils and water in creams, lotions, shampoos, and conditioners.
- Enhances product texture, stability, and skin feel.
- Helps disperse fragrances and active ingredients evenly.
- Industrial Applications
- Used in textile processing, detergents, and paints as emulsifiers and dispersants.
- Facilitates the formulation of emulsions and suspensions in various manufacturing processes.
Secondary Uses
- Agriculture
- Used as adjuvants in pesticide formulations to improve spreading and adhesion.
- Biomedical Research
- Employed as stabilizers in vaccine formulations and cell culture media.
- Lubricants and Coatings
- Improves miscibility and stability in lubricant and coating formulations.
- Improves miscibility and stability in lubricant and coating formulations.
KEY PRODUCT FEATURES
1. Basic Identification Attributes
- Chemical Name (IUPAC): Polyoxyethylene sorbitan esters (varies by fatty acid chain)
- Common/Trade Name: Polysorbate 20, Polysorbate 40, Polysorbate 60, Polysorbate 80 (most common types)
- CAS Number: Varies (e.g., Polysorbate 80: 9005-65-6)
- HS Code: 3402.19.00 (Surface-active agents)
- Synonyms: Tween (common trade name), Polyoxyethylene sorbitan fatty acid esters
2. Physical & Chemical Properties
- Physical State: Viscous liquid or semi-solid
- Color: Pale yellow to amber
- Odor: Mild, characteristic odor
- pH: Typically 6.0–8.0 in aqueous solution
- Solubility: Soluble in water and alcohol; forms stable emulsions
- HLB (Hydrophilic-Lipophilic Balance): Range from 8.6 to 16.7 depending on type (higher HLB = more hydrophilic)
- Density: Approx. 1.05 g/cm³
3. Safety & Hazard Attributes
- GHS Classification: Generally not classified as hazardous
- Toxicity: Low toxicity; considered safe for food and cosmetic use within regulatory limits
- Irritation Potential: Mild skin and eye irritant at high concentrations
- Flammability: Non-flammable
4. Storage & Handling Attributes
- Storage Conditions: Store in a cool, dry place away from direct sunlight and heat
- Container Type: Supplied in plastic drums, bottles, or bulk containers
- Shelf Life: Typically 2–3 years if stored properly
- Handling Precautions: Avoid inhalation of aerosols and prolonged skin contact
5. Regulatory & Compliance Attributes
- Complies with:
- FDA regulations for food-grade emulsifiers
- Cosmetic ingredient safety standards (e.g., EU Cosmetic Regulation)
- USP/NF monographs for pharmaceutical grades
- REACH and other international chemical safety regulations
- FDA regulations for food-grade emulsifiers
6. Environmental & Health Impact
- Biodegradability: Readily biodegradable
- Ecotoxicity: Low environmental impact when used as directed
- Bioaccumulation: Not expected to bioaccumulate
- Carcinogenicity/Mutagenicity: Not classified as hazardous
SAFETY HANDLING PRECAUTIONS
Safety Handling Precautions
- PPE Required: Gloves and safety goggles recommended during handling of concentrated material
- Handling Guidelines: Use in well-ventilated areas; avoid inhalation of mist or aerosols
- Storage Measures: Keep containers tightly closed; avoid contamination
First Aid Measures
- Inhalation: Move to fresh air if irritation occurs
- Skin Contact: Wash with soap and water; seek medical advice if irritation persists
- Eye Contact: Rinse thoroughly with water for at least 15 minutes; seek medical attention if irritation continues
- Ingestion: Rinse mouth; seek medical advice if discomfort or symptoms develop
Firefighting Measures
- Fire Hazards: Not flammable but can burn under fire conditions
- Extinguishing Media: Water spray, foam, dry chemical, or CO₂
- Special Precautions: Use standard protective equipment
- Hazardous Combustion Products: May produce carbon oxides and other toxic fumes during combustion
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Ceteareth 25 Ginonic
Ceteareth 25 Ginonic CSA 25 is a nonionic surfactant and emulsifier derived from the ethoxylation of cetearyl alcohol, incorporating approximately 20 ethylene oxide units per molecule. It appears as a white to off-white waxy solid or viscous liquid, depending on temperature and formulation. This emulsifier is widely used in cosmetic, pharmaceutical, and industrial formulations for its excellent ability to stabilize oil-in-water emulsions, improve texture, and enhance the sensory properties of finished products. Its high hydrophilic-lipophilic balance (HLB) makes it especially effective in forming stable emulsions and solubilizing lipophilic ingredients in aqueous phases. Ceteareth 20 is valued for its mildness, broad compatibility, and multifunctional performance.
Cetomacrogol PEG1000 (Ginonic CSA 20)
Cetomacrogol PEG (Ginonic CSA) is a polyethylene glycol-based nonionic surfactant and emulsifier with an average molecular weight of approximately 1000 Da. It appears as a white to off-white waxy solid or flakes with a neutral odor. This high-quality grade is widely used in cosmetic, pharmaceutical, and personal care formulations due to its excellent emulsifying, solubilizing, and moisturizing properties. Cetomacrogol PEG1000 (Ginonic CSA 20) facilitates stable oil-in-water emulsions, improves product texture and skin feel, and enhances the bioavailability of active ingredients. Its hydrophilic nature and compatibility with a wide range of ingredients make it a versatile additive in creams, lotions, ointments, and topical gels.
Cocodiethanolamide (CDEA)
Cocodiethanolamide (CDEA) is a viscous, amber to dark brown liquid derived from the reaction of coconut oil fatty acids with diethanolamine. It is a non-ionic surfactant and foam stabilizer commonly used in personal care and cleaning products. CDEA enhances foam quality, viscosity, and skin conditioning properties in formulations. Due to its excellent emulsifying and thickening abilities, it is widely used as a secondary surfactant to boost the performance of primary detergents. It is valued for its biodegradability, mildness, and compatibility with various surfactants and other ingredients in cosmetics and industrial formulations.
Emulsifier ( Emulgator) NP-9
Emulsifier ( Emulgator) NP-9 is a nonionic surfactant belonging to the family of Nonylphenol Ethoxylates (NPEs), specifically with an average of 9 ethylene oxide (EO) units. It is widely used as an effective emulsifying, wetting, dispersing, and solubilizing agent. NP-9 is typically a pale yellow to amber viscous liquid, soluble in water and various organic solvents. It is valued for its strong emulsifying ability to stabilize oil-in-water (O/W) and water-in-oil (W/O) emulsions, excellent detergency, and good compatibility with other surfactants and formulation ingredients. NP-9 is commonly employed in industrial, agricultural, cosmetic, pharmaceutical, and cleaning applications.
Emulsifying Wax Non ionic
Emulsifying Wax Non ionic is a self-emulsifying, non-ionic wax blend composed primarily of fatty alcohols (typically cetostearyl alcohol or stearyl alcohol) and non-ionic surfactants like polyethylene glycol (PEG) derivatives. It is used to stabilize oil-in-water (O/W) emulsions without relying on ionic charges, making it highly compatible with a wide range of ingredients, including both cationic and anionic components. This wax is commonly found in white, odorless solid flakes or pellets and is dispersible in hot water to form smooth, stable emulsions. It is widely used in cosmetic, pharmaceutical, and industrial applications where gentle emulsification, stability, and broad pH compatibility are needed.
Triethanolamine (TEA)
Triethanolamine (TEA) is a viscous, colorless to pale yellow liquid with a mild ammonia-like odor. It is a multifunctional organic compound widely used in cosmetics, pharmaceuticals, and industrial applications as a pH adjuster, emulsifier, surfactant, and corrosion inhibitor. Triethanolamine neutralizes fatty acids to form soaps and helps stabilize emulsions, making it essential in personal care formulations and various chemical manufacturing processes. Its versatility and compatibility with other ingredients make it a valuable additive in numerous industries.
Turkey Red Oil (Sulphated Castor Oil)
Turkey Red Oil (Sulphated Castor Oil), also known as Sulphated Castor Oil, is a water-soluble derivative of castor oil produced by the sulfonation of castor oil. It appears as a viscous, amber to dark brown liquid with excellent emulsifying, detergent, and wetting properties. Turkey Red Oil is widely used as a natural surfactant and emulsifier in various industrial and personal care applications. It is known for its biodegradability, mildness, and ability to stabilize oil-in-water emulsions. Traditionally used in textile processing as a softener and lubricant, it now finds broad usage in cosmetics, detergents, leather processing, and cleaning products due to its unique functional attributes.
