PVP Iodine 10%
PVP Iodine 10% is a water-soluble complex of polyvinylpyrrolidone (PVP) and iodine, widely used as a broad-spectrum antiseptic. It delivers controlled iodine release, providing effective antimicrobial action against bacteria, viruses, fungi, and protozoa. This preparation is favored for its ease of application, reduced irritation compared to tinctures, and stability in aqueous solutions. PVP Iodine 10% is commonly used in medical, veterinary, and personal care settings for disinfection and wound treatment.
Primary Uses
Medical & Healthcare
Used as a topical antiseptic for preoperative skin preparation and wound cleaning.
Applied in treatment and prevention of minor cuts, abrasions, burns, and infections.
Employed in surgical scrubs and hand sanitizers for healthcare professionals.
Dental Care
Used as an oral disinfectant in mouthwashes and gargles to reduce oral microbial load.
Applied in the management of oral mucosal infections and periodontal therapy.
Veterinary Medicine
Used for disinfecting animal skin and wounds.
Employed in surgical preparation and post-operative care in veterinary clinics.
Personal Care & Hygiene
Incorporated in antiseptic creams, ointments, and washes for household first aid.
Used in feminine hygiene products and skin cleansers for infection prevention.
Secondary Uses
Water Treatment
Occasionally used for disinfecting drinking water in emergency or field conditions.
Laboratory & Research
Used as a microbial control agent in microbiology labs and research settings.
Cosmetics
Incorporated in formulations requiring antimicrobial preservation without harsh solvents.
Food Industry
Employed in sanitizing food contact surfaces and equipment in food processing facilities (non-food additive).
 Basic Identification Attributes
- Chemical Name (IUPAC): Poly(1-vinyl-2-pyrrolidone)-iodine complex
- Common/Trade Name: PVP Iodine 10%
- CAS Number: 25655-41-8 (PVP), 7553-56-2 (iodine)
- HS Code: 3004.90.90
- Synonyms: Povidone-iodine 10%; Betadine (brand)
Physical & Chemical Properties
- Physical State: Aqueous solution
- Color & Odor: Brownish-red; characteristic iodine odor
- pH: Approximately 3.5–5.5
- Solubility: Soluble in water
- Iodine Content: Typically 10% available iodine by weight
Safety & Hazard Attributes
- GHS Classification: Eye irritant, skin sensitizer (depending on concentration)
- Toxicity: Low systemic toxicity when used topically; avoid ingestion and prolonged skin exposure
- Exposure Limits: Use as per recommended medical guidelines
Storage & Handling Attributes
- Storage Conditions: Store in a cool, dry place protected from light and heat
- Container Type: Supplied in plastic or glass bottles with secure caps
- Shelf Life: Typically 2 years if stored properly
- Handling Precautions: Avoid contact with eyes and mucous membranes; use gloves when applying to large wounds
Regulatory & Compliance Attributes
- Complies with USP, BP, and EP pharmacopoeial standards for antiseptics
- Approved by FDA and EMA for topical antiseptic use
- Manufactured in GMP-certified pharmaceutical facilities
Environmental & Health Impact
- Biodegradability: Biodegradable components; iodine may be toxic to aquatic life in large quantities
- Ecotoxicity: Moderate ecotoxicity; avoid disposal into waterways
- Bioaccumulation: Not significant
PPE Required: Gloves recommended during application; eye protection if splashing possible
Handling Guidelines: Use in well-ventilated areas; avoid ingestion and prolonged skin contact
Storage Measures: Keep containers tightly closed and stored in a dry, cool environment away from direct sunlight
First Aid Measures
Inhalation: Move to fresh air if respiratory irritation occurs
Skin Contact: Wash with soap and water; discontinue use if irritation develops
Eye Contact: Rinse immediately with plenty of water for at least 15 minutes; seek medical attention
Ingestion: Do not induce vomiting; seek immediate medical help
Firefighting Measures
Fire Hazards: Non-flammable aqueous solution
Extinguishing Media: Use water spray, foam, dry chemical, or COâ‚‚ on surrounding fire
Special Precautions: None specific; standard firefighting protective equipment recommended
Hazardous Combustion Products: May release iodine vapors if heated to decomposition