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PVP K 30 USP
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Pyrimethamine HCL Micronised
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PVP K 90 USP

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PVP K 90 USP (Polyvinylpyrrolidone K-90) is a high molecular weight water-soluble polymer widely used in pharmaceutical, cosmetic, and industrial applications. Known for its excellent film-forming, adhesive, and thickening properties, PVP K 90 is particularly valued where higher viscosity and stronger binding are required. This grade meets USP standards, ensuring purity and suitability for pharmaceutical use, especially in sustained-release formulations, suspensions, and topical products.

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Description

Primary Uses

Pharmaceutical Industry
Used as a binder in tablets and granules, providing enhanced mechanical strength due to its high molecular weight.

Functions as a suspending and viscosity-increasing agent in liquid formulations and injectables.

Employed in controlled-release formulations to regulate drug release kinetics.

Acts as a film former for protective coatings on tablets and topical products.

Cosmetics and Personal Care
Utilized as a thickener, stabilizer, and film former in creams, lotions, shampoos, and hair styling products.

Enhances moisture retention and skin feel in various skincare formulations.

Industrial Applications
Used as a dispersant and stabilizer in adhesives, inks, and paints.

Applied in the formulation of photographic chemicals and other specialty products.

Secondary Uses

Food Industry
Occasionally used as a stabilizer and emulsifier under regulatory approval.

Laboratory Uses
Serves as a matrix component in biochemical and molecular biology research.

PRODUCT KEY FEATURES

 Basic Identification Attributes

  • Chemical Name (IUPAC): Poly(1-vinyl-2-pyrrolidone)

  • Common/Trade Name: PVP K 90 USP

  • CAS Number: 9003-39-8

  • HS Code: 3906.90.10

  • Synonyms: Polyvinylpyrrolidone K-90; Povidone K90

Physical & Chemical Properties

  • Physical State: Fine white to off-white powder

  • Solubility: Soluble in water and some polar solvents

  • Molecular Weight: Approximately 360,000 Da (K value 90)

  • pH (1% solution): 4.0 – 7.0

  • Odor & Color: Odorless or slight characteristic odor; white powder

 

Safety & Hazard Attributes

  • GHS Classification: Not classified as hazardous

  • Toxicity: Low toxicity; generally non-irritant

  • Exposure Limits: Follow occupational safety guidelines for dust

Storage & Handling Attributes

  • Storage Conditions: Store in a cool, dry, well-ventilated area, away from moisture and incompatible substances

  • Container Type: Sealed bags or drums

  • Shelf Life: 2–3 years if stored properly

  • Handling Precautions: Avoid dust formation; use appropriate respiratory protection

 

Regulatory & Compliance Attributes

  • Complies with USP monograph for Polyvinylpyrrolidone

  • Generally Recognized As Safe (GRAS) for specified uses

  • Manufactured under GMP conditions

 

Environmental & Health Impact

  • Biodegradability: Readily biodegradable

  • Ecotoxicity: Low aquatic toxicity

  • Bioaccumulation: Not significant

SAFETY HANDLING PRECAUTIONS

PPE Required: Dust mask, gloves, and eye protection recommended

Handling Guidelines: Use in well-ventilated areas; minimize dust exposure

Storage Measures: Keep containers tightly sealed and stored in a dry environment away from moisture

 

First Aid Measures
Inhalation: Move to fresh air; seek medical attention if irritation occurs

Skin Contact: Wash with soap and water; seek medical advice if irritation develops

Eye Contact: Rinse eyes with plenty of water for 15 minutes; seek medical attention if needed

Ingestion: Rinse mouth; consult a physician if large quantities ingested

 

Firefighting Measures
Fire Hazards: Combustible dust may cause explosive atmospheres

Extinguishing Media: Water spray, foam, dry chemical, COâ‚‚

Special Precautions: Avoid dust accumulation; use respiratory and protective clothing

Hazardous Combustion Products: Carbon oxides, nitrogen oxides

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