Santophene( 4-chloro-2-Benzyl phenol)
Santophene (4-chloro-2-benzylphenol) is a chlorinated phenolic compound used primarily as a biocide and preservative in various industrial applications. It exhibits strong antimicrobial properties, effectively controlling the growth of bacteria, fungi, and algae. This compound is widely applied in coatings, paints, wood preservation, and water treatment to protect materials from microbial degradation and extend their service life.
Santophene (4-chloro-2-benzylphenol)
Primary Uses
- Industrial Biocide
- Used in paints, coatings, and varnishes to prevent microbial growth and spoilage.
- Employed as a wood preservative to protect against fungal decay and insect attack.
- Incorporated in cooling water systems and paper mills as a biocide to control microbial contamination.
- Preservative
- Utilized in adhesives and sealants to inhibit microbial degradation.
- Applied in leather processing to prevent bacterial and fungal growth.
Secondary Uses
- Agriculture
- Investigated as a potential pesticide or fungicide due to its antimicrobial properties.
- Research
- Used in microbiological studies to evaluate antimicrobial efficacy and resistance mechanisms.
1. Basic Identification Attributes
- Chemical Name (IUPAC): 4-chloro-2-benzylphenol
- Common/Trade Name: Santophene
- CAS Number: 118-92-3
- HS Code: 2907.19
- Synonyms: Chlorobenzylphenol; 4-chloro-2-(phenylmethyl)phenol
2. Physical & Chemical Properties
- Physical State: Solid (crystalline powder)
- Color & Odor: White to pale yellow; phenolic odor
- Melting Point: Approx. 80–85 °C
- Solubility: Slightly soluble in water; soluble in organic solvents such as ethanol and ether
3. Safety & Hazard Attributes
- GHS Classification: Harmful if swallowed; irritant to skin and eyes
- Toxicity: Moderate; handle with care to avoid exposure
- Exposure Limits: Follow safety guidelines for phenolic compounds
4. Storage & Handling Attributes
- Storage Conditions: Store in a cool, dry, well-ventilated area away from oxidizing agents and heat sources
- Container Type: Sealed, moisture-proof containers
- Shelf Life: Stable for 2–3 years under proper storage
- Handling Precautions: Use gloves and eye protection; avoid dust generation
5. Regulatory & Compliance Attributes
- Complies with relevant industrial biocide regulations
- Subject to chemical safety and environmental regulations in various jurisdictions
6. Environmental & Health Impact
- Biodegradability: Moderately biodegradable
- Ecotoxicity: Toxic to aquatic life; avoid environmental release
- Bioaccumulation: Potential for moderate bioaccumulation
Safety Handling Precautions
- PPE Required: Gloves, goggles, and protective clothing recommended
- Handling Guidelines: Work in well-ventilated areas; avoid inhalation and skin contact
- Storage Measures: Keep containers tightly closed and stored in a dry environment
First Aid Measures
- Inhalation: Move to fresh air; seek medical attention if respiratory irritation occurs
- Skin Contact: Wash immediately with soap and water; seek medical advice if irritation persists
- Eye Contact: Rinse thoroughly with water for 15 minutes; obtain medical attention if needed
- Ingestion: Do not induce vomiting; seek immediate medical care
Firefighting Measures
- Fire Hazards: Combustible solid; emits toxic fumes when heated or burned
- Extinguishing Media: Use foam, dry chemical, or CO₂
- Special Precautions: Wear full protective gear and self-contained breathing apparatus
- Hazardous Combustion Products: Carbon oxides, chlorine-containing compounds
Related products
Acticide EPW (Dry Film)
Acticide EPW is a VOC-free, water-based dry film biocide manufactured by Thor Group specifically formulated to protect exterior and interior water-based coatings, paints, and inks from surface fungal and algal growth. It appears as a white to off-white milky dispersion or suspension with a mild odor. The product is based on a synergistic blend of active ingredients including benzimidazole carbamate, 2-n-octyl-4-isothiazolin-3-one (OIT), and a urea derivative with AMME™ technology. This alkali-stable and UV-stable formulation is free from AOX (Adsorbable Organic Halogens) and VOC (Volatile Organic Compounds), making it suitable for low-VOC and environmentally conscious product formulations. Acticide EPW is manufactured for industrial use and is not intended for direct human consumption, medical applications, or food preservation.
Acticide HF (Incan)
Acticide HF is a proven, broad-spectrum industrial biocide manufactured by Thor Group specifically for in-can preservation of water-based industrial products. It is a clear, colorless to pale blue or pale green liquid with a mild odor, designed for easy incorporation into aqueous formulations. The product is based on a synergistic combination of active ingredients including 5-Chloro-2-methyl-4-isothiazolin-3-one (CIT), 2-Methyl-4-isothiazolin-3-one (MIT), and formaldehyde. This well-established formulation protects water-based formulations against bacteria, molds, and yeasts, ensuring product stability and extended shelf life across demanding conditions. Technical grade Acticide HF is manufactured for industrial use and is not intended for direct human consumption, medical applications, or food preservation.
Ammonium Cupric Chloride
Ammonium Cupric Chloride is a blue-green crystalline inorganic compound composed of copper, ammonium, and chloride ions. It is widely used as a source of copper in agricultural fungicides and bactericides, as well as in electroplating, chemical synthesis, and textile dyeing. Its antimicrobial properties make it valuable for controlling fungal and bacterial infections in plants. Additionally, it serves as a precursor in various industrial and laboratory applications.
Benzyl Konium Chloride
Benzyl Konium Chloride (BAC) 50% is a quaternary ammonium compound with potent antimicrobial and disinfectant properties. It is a cationic surfactant widely used for its bactericidal, fungicidal, and virucidal effects. This clear to pale yellow liquid concentrate is highly soluble in water and is commonly used in healthcare, sanitation, and industrial hygiene applications. BAC 50% solutions serve as active ingredients in disinfectants, sanitizers, and antiseptics due to their effectiveness against a broad spectrum of microorganisms.
Bronopol
Bronopol (2-Bromo-2-nitropropane-1,3-diol) is a water-soluble, white crystalline powder or granules with a slight odor. It is a synthetic antimicrobial agent widely used as a preservative in personal care products, pharmaceuticals, cosmetics, and industrial applications. Bronopol exhibits broad-spectrum bactericidal and fungicidal activity, making it effective against a wide range of microorganisms. It works by releasing active formaldehyde slowly, which disrupts microbial metabolism and reproduction.
Chlorine Tablets
Chlorine Tablets are solid, compressed forms of chlorine-releasing compounds, typically composed of stabilized trichloroisocyanuric acid (TCCA) or sodium dichloroisocyanurate (SDIC). These tablets are used primarily for water disinfection and sanitation due to their controlled and sustained release of chlorine. They appear as white to off-white, hard tablets with a mild chlorine odor. Chlorine Tablets are widely used in swimming pools, drinking water treatment, wastewater treatment, and industrial sanitization processes. Their slow dissolution ensures prolonged antimicrobial activity, providing effective control against bacteria, viruses, algae, and other pathogens.
Hydrogen Peroxide Food Grade
Hydrogen Peroxide Food Grade is a highly concentrated aqueous solution of hydrogen peroxide (H₂O₂), formulated specifically for use in food processing and related applications. It appears as a clear, colorless liquid with a slightly sharp, acrid odor. Renowned for its powerful oxidizing and bleaching properties, hydrogen peroxide is a strong antimicrobial agent and environmentally friendly disinfectant that decomposes into water and oxygen, leaving no harmful residues. The food-grade designation ensures compliance with strict purity standards, making it suitable for direct and indirect food contact uses, including sterilization, sanitation, and preservation.
Sodium Metabisulphite
Sodium Metabisulphite is a white crystalline powder widely used as an antioxidant, disinfectant, and preservative. It dissolves readily in water, releasing sulfur dioxide, which acts as a powerful antimicrobial and antioxidant agent. This chemical finds broad applications in food processing, water treatment, pharmaceuticals, and industrial manufacturing to prevent spoilage, control microbial growth, and protect equipment from corrosion.

Preservatives(food)
Flavor Enhancers
Acidulants
Sweeteners
Antioxidants
Colorants(food)
Nutraceutical Ingredients (food)
Nutrient Supplements
Emulsifiers
Collectors
Dust Suppressants
Explosives and Blasting Agents
Flocculants and Coagulants
Frothers
Leaching Agents
pH Modifiers
Precious Metal Extraction Agents
Antioxidants(plastic)
Colorants (Pigments, Dyes)
Fillers and Reinforcements
Flame Retardants
Monomers
Plasticizers
Polymerization Initiators
Stabilizers (UV, Heat)
Antifoaming Agents
Chelating Agents
Coagulants and Flocculants
Corrosion Inhibitors
Disinfectants and Biocides
Oxidizing Agents
pH Adjusters
Scale Inhibitors( water)
Antioxidants(cosmetic)
Emollients
Fragrances and Essential Oils
Humectants
Preservatives
Surfactants(cosmetic)
Thickeners
UV Filters
Fertilizers
Soil Conditioners
Plant Growth Regulators
Animal Feed Additives
Biostimulants
Pesticides (Herbicides, Insecticides, Fungicides)
Active Pharmaceutical Ingredients (APIs)
Excipients
Solvents(pharmaceutical)
Antibiotics
Antiseptics and Disinfectants
Vaccine Adjuvants
Nutraceutical Ingredients (pharmaceutical)
Analgesics & Antipyretics
Analytical Reagents
Solvents(lab)
Chromatography Chemicals
Spectroscopy Reagents
microbiology-and-cell-culture-reagents
Molecular Biology Reagents
Biochemical Reagents
Inorganic and Organic Standards
Laboratory Safety Chemicals
Specialty Laboratory Chemicals(Special Laboratory Equipment)
Demulsifiers
Hydraulic Fracturing Fluids
Scale Inhibitors(oil)
Surfactants(oil)
Drilling Fluids
Dyes and Pigments
Bleaching Agents
Softening Agents
Finishing Agents
Antistatic Agents
Admixtures
Waterproofing Agents
Sealants and Adhesives
Curing Compounds
Concrete Repair Chemicals
Anti-Corrosion Coatings
Surfactants(cleaning)
Builders
Enzymes
Solvents (Cleaning)
Fragrances
Electronic Chemicals
Catalysts
Lubricants
Photographic Chemicals
Refrigerants
Automotive chemicals
Pyrotechnic Chemicals
Biodegradable Surfactants
Bio-based Solvents
Renewable Polymers
Carbon Capture Chemicals
Wastewater Treatment Chemicals
Pigments
Solvents(paint)
Specialty Coatings
Binders/Resins
Additives
Driers
Anti-Corrosion Agents
Functional Coatings
Application-Specific Coatings
Leavening Agents
Dough Conditioners
Flour Treatments
Fat Replacers
Decoratives
Preservatives(baking)
Plasticizers & Softeners
Reinforcing Agents
Adhesion Promoters
Vulcanizing Agents
Antidegradants
Blowing Agents
Fillers & Extenders
Accelerators & Retarders