Simethicone Emulsion

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Simethicone Emulsion is a medical-grade, anti-foaming agent composed of polydimethylsiloxane and silicon dioxide in an emulsified form. Designed to reduce gas bubbles in the gastrointestinal tract, it provides rapid relief from bloating and discomfort. The emulsion formulation enhances bioavailability and mixing with bodily fluids.

Description

Uses

Primary Uses 

  • Gastrointestinal Treatments
  • Immediate relief of gas pain and bloating
  • Pre-treatment for abdominal diagnostic procedures (X-ray, endoscopy)
  • Management of functional dyspepsia
  • Adjunct in GERD therapy
  • Infant Care
  • Treatment of colic and infant gas discomfort
  • Prevention of feeding-related gas accumulation

Secondary Uses 

  • Veterinary Medicine
  • Relief of ruminant bloat in cattle
  • Treatment of gas accumulation in horses
  • Pharmaceutical Manufacturing
  • Defoaming agent in fermentation processes
  • Additive in antacid formulations

 

PRODUCT KEY FEATURES

Basic Identification Attributes

  • Chemical Name: Polymethylsiloxane hydrated silica
  • CAS Number: 8050-81-5
  • INCI Name: Dimethicone
  • HS Code: 3910.00.00
  • Synonyms: Activated dimethicone, anti-flatulent agent

Physical & Chemical Properties

  • Physical State: Milky white emulsion
  • Color: White to off-white
  • Odor: Characteristic mild silicone odor
  • Viscosity: 100-500 cps
  • pH: 6.0-7.5
  • Density: 1.00-1.05 g/cm³

Safety & Hazard Attributes

  • GHS Classification: Non-hazardous
  • Toxicity: Non-toxic (LD50 >5000 mg/kg)
  • Exposure Limits: No occupational exposure limits established

Storage & Handling Attributes

  • Storage Conditions:
  • Store at 15-30°C
  • Protect from freezing
  • Container Type: HDPE bottles with phenolic caps
  • Shelf Life: 24 months unopened
  • Handling Precautions:
  • Avoid prolonged skin contact

Regulatory & Compliance Attributes

  • Complies with:
  • USP/NF monograph standards
  • FDA 21 CFR 332.30
  • EP 10.0 requirements

Environmental & Health Impact

  • Biodegradability: Not readily biodegradable
  • Ecotoxicity: Low environmental impact

 

SAFETY HANDLING PRECAUTIONS

Safety Handling Precautions

  • PPE Required: Safety glasses, nitrile gloves
  • Handling Guidelines: Standard laboratory practices

First Aid Measures

  • Eye Contact: Rinse with water for 15 minutes
  • Ingestion: No treatment needed (non-toxic)

Firefighting Measures

  • Fire Hazards: Non-flammable
  • Extinguishing Media: Use appropriate media for surrounding fire