Tripolidine HCL BP

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Tripolidine Hydrochloride BP is a high-purity pharmaceutical-grade antihistamine used primarily to treat allergic conditions. It acts as a selective H1 histamine receptor antagonist, helping to relieve symptoms such as itching, sneezing, nasal congestion, and hives by blocking the action of histamine. The British Pharmacopoeia (BP) grade ensures compliance with stringent quality standards required for medicinal use. Tripolidine HCL is commonly formulated into tablets and syrups for effective allergy management.

Description

Primary Uses
Pharmaceutical Industry:

Active ingredient in antihistamine medications for treating allergic rhinitis, urticaria (hives), conjunctivitis, and other hypersensitivity reactions.

Used in formulations for seasonal allergies and chronic allergic conditions.

Secondary Uses
Combination Drug Formulations:

Often combined with decongestants, analgesics, or other cold and allergy medication components to provide multi-symptom relief.

Veterinary Medicine:

Utilized occasionally in veterinary formulations to manage allergic responses in animals.

Research & Development:

Used in pharmacological research to study histamine receptor antagonism and develop improved allergy therapeutics.

 

 

PRODUCT KEY FEATURES

Chemical Name (IUPAC): 1-(4-Methylphenyl)-4-(1-pyrrolidinyl)-2-pyridinamine hydrochloride

Common/Trade Name: Tripolidine HCL BP

CAS Number: 3587-57-5

HS Code: 2933.69.90

Synonyms: Tripolidine Hydrochloride

 

Physical & Chemical Properties
Physical State: Fine crystalline powder

Color & Odor: White to off-white; odorless

Melting Point: Approximately 190-192 °C

Solubility: Soluble in water and alcohol

Purity: Meets British Pharmacopoeia (BP) specifications

 

Safety & Hazard Attributes
GHS Classification: Not classified as hazardous under standard pharmaceutical handling

Toxicity: Low toxicity; overdose may cause sedation, dry mouth, or dizziness

Exposure Limits: Follow pharmaceutical industry safety standards

 

Storage & Handling Attributes
Storage Conditions: Store in a cool, dry, and well-ventilated place away from direct sunlight and moisture

Container Type: Sealed, moisture-proof containers such as HDPE drums or bottles

Shelf Life: Typically 24 months under proper storage

Handling Precautions: Avoid dust inhalation and contact with skin or eyes

 

Regulatory & Compliance Attributes
Complies with British Pharmacopoeia (BP) standards

Produced under Good Manufacturing Practices (GMP) for pharmaceutical use

Registered with relevant regulatory authorities for medicinal applications

 

Environmental & Health Impact
Biodegradability: Not readily biodegradable; proper disposal recommended

Ecotoxicity: Limited data; avoid environmental release

Bioaccumulation: Not significant

SAFETY HANDLING FEATURES

PPE Required: Use gloves, dust mask, and eye protection during handling

Handling Guidelines: Use adequate ventilation to minimize dust exposure

Storage Measures: Keep containers tightly closed and protected from moisture

 

First Aid Measures
Inhalation: Move to fresh air; seek medical advice if breathing difficulties occur

Skin Contact: Wash with soap and water thoroughly

Eye Contact: Rinse immediately with plenty of water; seek medical attention if irritation persists

Ingestion: Rinse mouth and seek immediate medical attention

 

Firefighting Measures
Fire Hazards: Combustible under fire conditions

Extinguishing Media: Use foam, dry chemical, or carbon dioxide extinguishers

Hazardous Combustion Products: Carbon oxides, nitrogen oxides