Tripolidine HCL BP
Tripolidine Hydrochloride BP is a high-purity pharmaceutical-grade antihistamine used primarily to treat allergic conditions. It acts as a selective H1 histamine receptor antagonist, helping to relieve symptoms such as itching, sneezing, nasal congestion, and hives by blocking the action of histamine. The British Pharmacopoeia (BP) grade ensures compliance with stringent quality standards required for medicinal use. Tripolidine HCL is commonly formulated into tablets and syrups for effective allergy management.
Primary Uses
Pharmaceutical Industry:
Active ingredient in antihistamine medications for treating allergic rhinitis, urticaria (hives), conjunctivitis, and other hypersensitivity reactions.
Used in formulations for seasonal allergies and chronic allergic conditions.
Secondary Uses
Combination Drug Formulations:
Often combined with decongestants, analgesics, or other cold and allergy medication components to provide multi-symptom relief.
Veterinary Medicine:
Utilized occasionally in veterinary formulations to manage allergic responses in animals.
Research & Development:
Used in pharmacological research to study histamine receptor antagonism and develop improved allergy therapeutics.
Chemical Name (IUPAC): 1-(4-Methylphenyl)-4-(1-pyrrolidinyl)-2-pyridinamine hydrochloride
Common/Trade Name: Tripolidine HCL BP
CAS Number: 3587-57-5
HS Code: 2933.69.90
Synonyms: Tripolidine Hydrochloride
Physical & Chemical Properties
Physical State: Fine crystalline powder
Color & Odor: White to off-white; odorless
Melting Point: Approximately 190-192 °C
Solubility: Soluble in water and alcohol
Purity: Meets British Pharmacopoeia (BP) specifications
Safety & Hazard Attributes
GHS Classification: Not classified as hazardous under standard pharmaceutical handling
Toxicity: Low toxicity; overdose may cause sedation, dry mouth, or dizziness
Exposure Limits: Follow pharmaceutical industry safety standards
Storage & Handling Attributes
Storage Conditions: Store in a cool, dry, and well-ventilated place away from direct sunlight and moisture
Container Type: Sealed, moisture-proof containers such as HDPE drums or bottles
Shelf Life: Typically 24 months under proper storage
Handling Precautions: Avoid dust inhalation and contact with skin or eyes
Regulatory & Compliance Attributes
Complies with British Pharmacopoeia (BP) standards
Produced under Good Manufacturing Practices (GMP) for pharmaceutical use
Registered with relevant regulatory authorities for medicinal applications
Environmental & Health Impact
Biodegradability: Not readily biodegradable; proper disposal recommended
Ecotoxicity: Limited data; avoid environmental release
Bioaccumulation: Not significant
PPE Required: Use gloves, dust mask, and eye protection during handling
Handling Guidelines: Use adequate ventilation to minimize dust exposure
Storage Measures: Keep containers tightly closed and protected from moisture
First Aid Measures
Inhalation: Move to fresh air; seek medical advice if breathing difficulties occur
Skin Contact: Wash with soap and water thoroughly
Eye Contact: Rinse immediately with plenty of water; seek medical attention if irritation persists
Ingestion: Rinse mouth and seek immediate medical attention
Firefighting Measures
Fire Hazards: Combustible under fire conditions
Extinguishing Media: Use foam, dry chemical, or carbon dioxide extinguishers
Hazardous Combustion Products: Carbon oxides, nitrogen oxides

Preservatives(food)
Flavor Enhancers
Acidulants
Sweeteners
Antioxidants
Colorants(food)
Nutraceutical Ingredients (food)
Nutrient Supplements
Emulsifiers
Collectors
Dust Suppressants
Explosives and Blasting Agents
Flocculants and Coagulants
Frothers
Leaching Agents
pH Modifiers
Precious Metal Extraction Agents
Antioxidants(plastic)
Colorants (Pigments, Dyes)
Fillers and Reinforcements
Flame Retardants
Monomers
Plasticizers
Polymerization Initiators
Stabilizers (UV, Heat)
Antifoaming Agents
Chelating Agents
Coagulants and Flocculants
Corrosion Inhibitors
Disinfectants and Biocides
Oxidizing Agents
pH Adjusters
Scale Inhibitors( water)
Antioxidants(cosmetic)
Emollients
Fragrances and Essential Oils
Humectants
Preservatives
Surfactants(cosmetic)
Thickeners
UV Filters
Fertilizers
Soil Conditioners
Plant Growth Regulators
Animal Feed Additives
Biostimulants
Pesticides (Herbicides, Insecticides, Fungicides)
Active Pharmaceutical Ingredients (APIs)
Excipients
Solvents(pharmaceutical)
Antibiotics
Antiseptics and Disinfectants
Vaccine Adjuvants
Nutraceutical Ingredients (pharmaceutical)
Analgesics & Antipyretics
Analytical Reagents
Solvents(lab)
Chromatography Chemicals
Spectroscopy Reagents
microbiology-and-cell-culture-reagents
Molecular Biology Reagents
Biochemical Reagents
Inorganic and Organic Standards
Laboratory Safety Chemicals
Specialty Laboratory Chemicals(Special Laboratory Equipment)
Demulsifiers
Hydraulic Fracturing Fluids
Scale Inhibitors(oil)
Surfactants(oil)
Drilling Fluids
Dyes and Pigments
Bleaching Agents
Softening Agents
Finishing Agents
Antistatic Agents
Admixtures
Waterproofing Agents
Sealants and Adhesives
Curing Compounds
Concrete Repair Chemicals
Anti-Corrosion Coatings
Surfactants(cleaning)
Builders
Enzymes
Solvents (Cleaning)
Fragrances
Electronic Chemicals
Catalysts
Lubricants
Photographic Chemicals
Refrigerants
Automotive chemicals
Pyrotechnic Chemicals
Biodegradable Surfactants
Bio-based Solvents
Renewable Polymers
Carbon Capture Chemicals
Wastewater Treatment Chemicals
Pigments
Solvents(paint)
Specialty Coatings
Binders/Resins
Additives
Driers
Anti-Corrosion Agents
Functional Coatings
Application-Specific Coatings
Fresh Herbs
Ground Spices
Whole Spices
Spice Blends
Dried Herbs
Leavening Agents
Dough Conditioners
Flour Treatments
Fat Replacers
Decoratives
Preservatives(baking)
Plasticizers & Softeners
Reinforcing Agents
Adhesion Promoters
Vulcanizing Agents
Antidegradants
Blowing Agents
Fillers & Extenders
Accelerators & Retarders