Chlorhexidine Digluconate

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Chlorhexidine Digluconate is a concentrated aqueous solution of chlorhexidine salt (digluconate form), a potent broad-spectrum antimicrobial agent. It is a clear to slightly yellow viscous liquid with a mild characteristic odor. This antiseptic and disinfectant is widely used in medical, personal care, and industrial applications for its ability to effectively kill bacteria, fungi, and some viruses by disrupting microbial cell membranes. Chlorhexidine Digluconate is valued for its residual antimicrobial activity, low toxicity, and compatibility with various formulations.

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Category: Antiseptics and Disinfectants Tags: Antiseptic solution, Broad-spectrum disinfectant, Chlorhexidine digluconate, Clear to slightly yellow liquid, Hospital disinfectants, Medical antiseptics, Wound disinfectants

Description

Table of Contents

Chlorhexidine Digluconate

Primary Uses

Healthcare and Medical

Used as a surgical scrub and skin antiseptic to reduce microbial flora before invasive procedures.
Employed in oral care products such as mouthwashes and dental gels to control plaque and gingivitis.
Utilized in wound care and antiseptic creams to prevent infections.
Incorporated in hand sanitizers and disinfectants for healthcare workers and patient environments.

Personal Care

Formulated into skin cleansers, deodorants, and feminine hygiene products for antimicrobial protection.
Used in baby wipes and sanitizing wipes for effective microbial control without harsh chemicals.

Industrial Applications

Used in disinfectants and sanitizers for surfaces in food processing and pharmaceutical manufacturing.
Applied in water treatment systems as a biocide to control microbial contamination.

Secondary Uses

Veterinary Medicine

Used in antiseptic treatments for animals, including preoperative skin preparation and wound cleansing.

Textile Industry

Incorporated into antimicrobial textile treatments to inhibit bacterial growth and odors in fabrics.

Cosmetics

Included in preservative systems for cosmetic formulations to enhance microbial stability.

KEY PRODUCT FEATURES

1. Basic Identification Attributes

Chemical Name (IUPAC): 1,1'-Hexamethylenebis[5-(4-chlorophenyl)biguanide] digluconate
Common/Trade Name: Chlorhexidine Digluconate 20%
CAS Number: 18472-51-0
HS Code: 3808.94.00
Molecular Formula: C22H30Cl2N10·2C6H12O7 (digluconate salt)
Molecular Weight: 898.77 g/mol (digluconate salt)
Synonyms:
- CHG 20%
- Chlorhexidine gluconate solution

2. Physical & Chemical Properties

Physical State: Viscous liquid
Color & Odor: Clear to slightly yellow; mild characteristic odor
pH: Typically 5.5 – 7.0
Solubility: Completely soluble in water
Density: Approximately 1.05 g/cm³ at 20°C
Stability: Stable under normal storage conditions; sensitive to strong oxidizers

3. Safety & Hazard Attributes

Hazard Class (GHS): Not classified as hazardous under normal use; may cause skin and eye irritation
NFPA Ratings:
- Health: 2
- Flammability: 0
- Reactivity: 0
Exposure Limits: Avoid prolonged skin contact and inhalation of aerosols
Toxicity: Low toxicity; safe at recommended concentrations
Reactivity: Stable; avoid contact with strong oxidizing agents

4. Storage & Handling Attributes

Storage Conditions: Store in a cool, dry place away from direct sunlight and incompatible materials
Container Type: Polyethylene or glass containers with tight seals
Shelf Life: Typically 2 years if stored properly
Special Handling: Use gloves and eye protection; avoid aerosol formation

5. Regulatory & Compliance Attributes

FDA Status: Approved for use in antiseptic and disinfectant products
REACH Status: Registered
Transportation: Not regulated as hazardous material
Waste Disposal: Dispose according to local regulations; avoid release into waterways

6. Environmental & Health Impact

Ecotoxicity: Moderate toxicity to aquatic organisms; avoid discharge into environment
Persistence: Biodegradable under aerobic conditions
Bioaccumulation: Low potential for bioaccumulation
Carcinogenicity/Mutagenicity: Not classified as carcinogenic or mutagenic
Biodegradability: Readily biodegradable

SAFETY HANDLING PRECAUTIONS

Safety Handling Precautions

PPE: Use gloves, goggles, and protective clothing during handling
Handling: Avoid skin and eye contact; do not ingest; work in well-ventilated areas
Storage: Keep container tightly closed; store away from incompatible substances
Hygiene: Wash hands thoroughly after use; do not eat, drink, or smoke while handling

First Aid Measures

Inhalation: Move to fresh air; seek medical attention if respiratory irritation occurs
Skin Contact: Wash affected area with plenty of water and soap; seek medical advice if irritation develops
Eye Contact: Rinse cautiously with water for several minutes; seek medical attention if irritation persists
Ingestion: Do not induce vomiting; rinse mouth and seek immediate medical attention

Firefighting Measures

Fire Hazards: Non-flammable
Extinguishing Media: Use water spray, foam, or dry chemical extinguishers as appropriate for surrounding fire
Special Precautions: Firefighters should wear protective gear and self-contained breathing apparatus if necessary
Decomposition Products: May release toxic gases such as hydrogen chloride if heated to decomposition