Ellagic Acid Amaris Chemicals
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Ellagic Acid

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Ellagic Acid is a naturally occurring polyphenolic compound found in numerous fruits, nuts, and vegetables such as pomegranates, strawberries, raspberries, walnuts, and cranberries. It is a potent antioxidant known for its ability to scavenge free radicals and chelate metal ions. Due to its significant anti-inflammatory, anti-carcinogenic, and anti-viral properties, Ellagic Acid has gained extensive interest in pharmaceutical, nutraceutical, cosmetic, and food industries. It appears as a yellow to light brown crystalline powder, insoluble in water but soluble in organic solvents like ethanol and DMSO.

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Description

Ellagic Acid

Primary Uses 

  1. Pharmaceuticals & Nutraceuticals
  • Utilized as an active ingredient for its antioxidant and anti-inflammatory effects.
  • Employed in formulations aimed at cancer prevention and as adjunct therapy due to its anti-proliferative properties.
  • Investigated for potential antiviral applications including HIV and herpes simplex viruses.
  • Used in dietary supplements for general health and immune support.
  1. Cosmetics & Personal Care
  • Incorporated in anti-aging skin care products for its ability to protect skin from oxidative damage and UV-induced aging.
  • Used in formulations targeting hyperpigmentation and skin brightening due to its melanin synthesis inhibition.
  • Acts as an anti-inflammatory agent soothing irritated or sensitive skin.
  1. Food Industry
  • Applied as a natural antioxidant additive in food preservation to extend shelf life and prevent lipid peroxidation.
  • Used as a functional ingredient in health foods, beverages, and supplements.
  1. Research & Analytical Uses
  • Used in biochemical research to study antioxidant mechanisms and as a standard compound in polyphenol analysis.

Secondary Uses 

  1. Agriculture
  • Explored as a natural plant growth regulator and for potential pest resistance due to its antimicrobial properties.
  1. Biomedical Research
  • Investigated in tissue engineering and regenerative medicine for its cell-protective effects.
KEY PRODUCT FEATURES

1. Basic Identification Attributes

  • Chemical Name (IUPAC): 2,3,7,8-Tetrahydroxy-[1]benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione
  • Common/Trade Name: Ellagic Acid
  • CAS Number: 476-66-4
  • HS Code: 2934.99.99
  • Molecular Formula: C₁₄H₆O₈
  • Synonyms:
    • 4,4',5,5',6,6'-Hexahydroxydiphenic acid dilactone
    • 2,3,7,8-Tetrahydroxychromeno[5,4,3-cde]chromene-5,10-dione

2. Physical & Chemical Properties

  • Physical State: Crystalline powder
  • Color & Odor: Yellow to light brown; odorless
  • Melting Point: Approximately 300°C (decomposes)
  • Solubility: Insoluble in water; soluble in ethanol, methanol, DMSO, and alkaline solutions
  • Stability: Stable under normal conditions; sensitive to strong acids and bases

3. Safety & Hazard Attributes

  • Hazard Class (GHS): Not classified as hazardous
  • Toxicity: Low toxicity; generally safe in topical and oral use at recommended doses
  • Exposure Limits: Not established

4. Storage & Handling Attributes

  • Storage Conditions: Store in cool, dry, dark place in tightly sealed containers
  • Container Type: Glass or plastic bottles with airtight caps
  • Shelf Life: 2–3 years if stored properly
  • Handling Precautions: Avoid dust inhalation and prolonged skin contact

5. Regulatory & Compliance Attributes

  • Approved as a dietary supplement ingredient in many regions
  • Compliant with food safety and cosmetic regulations globally

6. Environmental & Health Impact

  • Biodegradability: Biodegradable under environmental conditions
  • Ecotoxicity: Low
  • Bioaccumulation: Not expected
  • Carcinogenicity/Mutagenicity: Not classified as carcinogenic or mutagenic
SAFETY HANDLING PRECAUTIONS

Safety Handling Precautions

PPE Required:

  • Dust mask or respirator (for powder handling)
  • Safety goggles
  • Gloves (nitrile or latex)
  • Protective clothing or lab coat

Handling Guidelines:

  • Handle in well-ventilated areas
  • Avoid dust generation and inhalation
  • Avoid prolonged skin contact
  • Use closed systems or local exhaust ventilation when available

Storage Measures:

  • Keep container tightly closed
  • Store away from strong oxidizers and bases
  • Protect from light and moisture

Hygiene Practices:

  • Wash hands after handling
  • Do not eat, drink, or smoke in handling areas
  • Clean spills promptly to avoid dust spread

First Aid Measures

  • Inhalation: Move to fresh air; seek medical attention if irritation persists
  • Skin Contact: Wash thoroughly with soap and water; seek medical attention if irritation develops
  • Eye Contact: Rinse with plenty of water for 15 minutes; seek medical advice if irritation persists
  • Ingestion: Rinse mouth; not expected to be toxic, but seek medical attention if large amounts ingested

Firefighting Measures

  • Fire Hazards: Non-flammable
  • Extinguishing Media: Water spray, foam, dry chemical, or carbon dioxide
  • Special Precautions: Use standard protective equipment
  • Decomposition Products: May emit carbon monoxide, carbon dioxide, and other organic vapors upon decomposition

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