Ethylvanilin

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Ethylvanilin (3-Ethoxy-4-hydroxybenzaldehyde) is a synthetic aromatic aldehyde widely used as a flavoring agent and fragrance ingredient. It is a white to pale yellow crystalline powder with a strong, sweet vanilla-like odor, but more intense than natural vanillin. Ethylvanillin offers excellent flavor stability, solubility in alcohol and oils, and is valued for its enhanced vanilla aroma in food, beverage, cosmetics, and pharmaceutical formulations. Due to its potent scent and flavor profile, it is a preferred substitute or complement to natural vanilla extract.

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Categories: Fragrances and Essential Oils, Excipients, Flavor Enhancers, Nutraceutical Ingredients (pharmaceutical) Tags: Cosmetic fragrances, Ethylvanillin, Food flavoring, Nutraceutical sweeteners, Pharmaceutical syrups, Synthetic vanilla flavor

Description

Table of Contents

Ethylvanilin

Primary Uses

Food & Beverage Industry
- Used as a flavor enhancer in bakery products, confectionery, chocolates, dairy items, and beverages to impart a rich vanilla aroma.
- Employed in flavor formulations for ice creams, puddings, syrups, and soft drinks.
- Acts as a masking agent to cover undesirable odors and enhance overall sensory profiles.
Fragrance & Perfumery
- Incorporated in perfumes, colognes, and scented products for its sweet, creamy, and long-lasting vanilla scent.
- Used in soaps, lotions, deodorants, and personal care products to provide warm vanilla notes.
- Utilized in aromatherapy blends and scented candles.
Pharmaceuticals
- Added as a flavoring agent in syrups, lozenges, chewable tablets, and oral medications to improve palatability and patient compliance.
- Sometimes used in topical formulations for its pleasant aroma.
Cosmetics & Personal Care
- Used in lip balms, creams, body lotions, and hair care products for fragrance enhancement.
- Functions as a scent modifier or base note in complex fragrance compositions.

Secondary Uses

Food Packaging & Processing
- Employed as an additive in packaging materials to impart vanilla scent or mask packaging odors.
- Used in aroma release systems and controlled flavor delivery mechanisms.
Household Products
- Incorporated in air fresheners, fabric softeners, and cleaning agents for a sweet vanilla fragrance.
Tobacco Industry
- Added as a flavor additive in tobacco products and e-liquids to create vanilla flavor variants.
Chemical Intermediate
- Used in organic synthesis for derivatives and specialty chemicals requiring aromatic aldehyde functionality.

PRODUCT KEY FEATURES

Basic Identification Attributes
- Chemical Name (IUPAC): 3-Ethoxy-4-hydroxybenzaldehyde
- Common/Trade Name: Ethylvanillin
- CAS Number: 121-32-4
- HS Code: 2914.39.00
- Molecular Formula: C9H10O3
- Synonyms: Ethyl vanillin, Vanillin ethyl ether, 3-Ethoxy-4-hydroxybenzaldehyde
Physical & Chemical Properties
- Physical State: Crystalline powder
- Color: White to pale yellow
- Odor: Strong sweet vanilla aroma
- Melting Point: 77–79°C
- Boiling Point: 297°C (decomposes)
- Density: ~1.23 g/cm³
- Solubility: Soluble in alcohol, oils, and organic solvents; sparingly soluble in water
- Stability: Stable under normal conditions; sensitive to strong acids and bases
Safety & Hazard Attributes
- Hazard Class (GHS): Not classified as hazardous but may cause mild skin or eye irritation
- Toxicity: Low acute toxicity; ingestion in large amounts not advised
- Exposure Limits: No specific occupational exposure limits established
Storage & Handling Attributes
- Storage Conditions: Store in a cool, dry, well-ventilated area away from light and moisture
- Container Type: Sealed glass or plastic containers, moisture-proof packaging
- Shelf Life: 24 months if stored properly
- Handling Precautions: Avoid dust formation, minimize inhalation, and prevent eye contact
Regulatory & Compliance Attributes
- FDA Status: Generally recognized as safe (GRAS) for use as a flavoring agent
- EFSA Approval: Approved as a flavoring substance in the EU
- Compliance: Meets food-grade specifications and purity standards
- Usage Restrictions: Used within regulated concentration limits in food and cosmetics
Environmental & Health Impact
- Biodegradability: Readily biodegradable
- Ecotoxicity: Low toxicity to aquatic organisms
- Bioaccumulation: Not expected
- Carcinogenicity/Mutagenicity: Not classified as carcinogenic or mutagenic

SAFETY HANDLING PRECAUTIONS

Safety Handling Precautions

Personal Protective Equipment (PPE):
- Gloves (nitrile or latex)
- Safety goggles
- Dust mask or respirator in dusty environments
- Lab coat or protective clothing
Handling Guidelines:
- Use in well-ventilated areas
- Avoid dust inhalation and contact with skin and eyes
- Prevent dust accumulation and spills
Storage Measures:
- Keep containers tightly sealed
- Protect from moisture, light, and heat
- Store away from incompatible substances (strong oxidizers)
Hygiene Practices:
- Wash hands after handling
- Avoid eating, drinking, or smoking near handling areas
- Clean surfaces and equipment after use

First Aid Measures

Inhalation:
- Move to fresh air; seek medical attention if breathing difficulties or irritation occur
Skin Contact:
- Wash with soap and water; seek medical advice if irritation develops
Eye Contact:
- Rinse eyes thoroughly with water for 15 minutes; consult physician if irritation persists
Ingestion:
- Rinse mouth; do not induce vomiting; seek immediate medical help if large quantities ingested

Firefighting Measures

Fire Hazards:
- Combustible solid; emits toxic fumes upon burning
Extinguishing Media:
- Use dry chemical, foam, carbon dioxide (CO₂), or water spray
Special Precautions:
- Firefighters should wear protective gear and self-contained breathing apparatus if necessary
Decomposition Products:
- Carbon monoxide, carbon dioxide, and aromatic aldehyde fragments