Isopropyl Myristate Extra Pure
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Isopropyl Myristate Extra Pure is a high-purity ester derived from isopropyl alcohol and myristic acid, commonly used for its excellent solvent and emollient properties. It appears as a colorless to slightly yellow, oily liquid with a faint odor. In laboratory and cosmetic settings, it serves as a solvent and carrier for active ingredients, particularly in topical formulations, where it enhances skin absorption without leaving a greasy residue. Its purity makes it suitable for precise formulation work in pharmaceutical, cosmetic, and personal care research. Isopropyl Myristate is also used in the preparation of perfumes and as a penetration enhancer in transdermal drug delivery systems.
Isopropyl Myristate Extra Pure
Primary Uses
- Solvent for Drug Delivery Studies:
Widely used as a non-polar solvent and penetration enhancer in transdermal drug delivery experiments, especially in formulation labs. - Emollient in Cosmetic Formulation Research:
Serves as a model emollient in laboratory studies focused on the development of creams, lotions, and topical formulations. - Carrier Compound in Fragrance and Oil Studies:
Used to dissolve fragrances and essential oils in analytical research related to perfumery and personal care products.
Secondary Uses
- Skin Permeation Experiments:
Commonly used in dermatological and pharmaceutical research to evaluate skin absorption and diffusion rates of active compounds. - Standard in Stability Testing:
Applied in experiments testing the stability of emulsions and cosmetic formulations under various environmental conditions. - Non-volatile Component in Controlled Release Systems:
Studied in labs exploring slow-release delivery systems for pharmaceuticals or active ingredients.
1. Basic Identification Attributes
- Product Name: Isopropyl Myristate
- Chemical Name: Propan-2-yl tetradecanoate
- Grade: Extra Pure
- Chemical Formula: C₁₇H₃₄O₂
- Molecular Weight: 270.45 g/mol
- CAS Number: 110-27-0
- Appearance: Clear, colorless to pale yellow oily liquid
- Odor: Faint, characteristic ester odor
2. Composition
- Purity: ≥99% (Extra Pure grade)
- Main Component: Isopropyl Myristate
- Impurities: Trace esters or alcohols (very low in lab grade)
3. Physical & Chemical Properties
- Boiling Point: ~167 °C at 10 mmHg
- Melting Point: ~-5 °C
- Flash Point: ~145 °C (closed cup)
- Density: ~0.85 g/cm³ at 25 °C
- Solubility: Insoluble in water; miscible with alcohols, oils, and organic solvents
- Viscosity: Low to medium
- Stability: Stable under normal lab conditions
4. Safety & Hazard Attributes
- GHS Classification:
✅ Not classified as hazardous under normal laboratory use - Hazard Statements:
- Not expected to be hazardous
- May cause mild skin or eye irritation with prolonged contact
- PPE Requirements:
- Lab coat
- Gloves (nitrile recommended)
- Safety goggles
- First Aid Measures:
- Skin Contact: Wash with soap and water
- Eye Contact: Rinse thoroughly with water for several minutes
- Inhalation: Move to fresh air (not volatile, low risk)
- Ingestion: Rinse mouth; seek medical advice if discomfort persists
- Fire Hazards:
- Combustible at high temperatures
- Use dry chemical, CO₂, or foam to extinguish
5. Storage & Handling Attributes
- Storage Conditions:
- Store in tightly closed container
- Keep in a cool, dry, well-ventilated place
- Protect from direct sunlight and strong oxidizers
- Handling Tips:
- Avoid contact with eyes
- Wash hands after use
- No special ventilation required under standard lab use
6. Laboratory Applications
- Primary Uses:
- Solvent and carrier in drug delivery systems
- Component in formulation testing (cosmetic and pharmaceutical)
- Penetration enhancer in transdermal delivery studies
- Used to dissolve lipophilic substances in experiments
- Secondary Uses:
- Emollient in in-vitro skin compatibility studies
- Standard in cosmetic stability and degradation testing
- Extraction solvent in certain fat or oil-based analysis
- Inert medium in controlled-release formulations
SAFETY PRECAUTIONS
Personal Protective Equipment (PPE):
- Wear a lab coat, nitrile gloves, and protective goggles.
- Use in a well-ventilated area or fume hood to prevent inhalation of vapors.
Handling:
- Avoid contact with skin and eyes.
- Do not inhale vapors or mist.
- Practice good hygiene—wash hands thoroughly after handling.
Storage:
- Store in a tightly sealed container in a cool, dry, and well-ventilated place.
- Keep away from heat sources, open flames, and incompatible materials like strong oxidizers.
FIRST AID MEASURES
Inhalation:
- Remove the person to fresh air.
- Get medical attention if symptoms persist.
Skin Contact:
- Wash with soap and water.
- Remove contaminated clothing.
- Seek medical advice if irritation or sensitization occurs.
Eye Contact:
- Rinse cautiously with water for several minutes.
- Remove contact lenses if present and easy to do.
- Seek medical attention if irritation persists.
Ingestion:
- Rinse mouth with water.
- Do not induce vomiting.
- Seek immediate medical advice.
FIRE FIGHTING MEASURES
Flammability:
- Combustible liquid—can catch fire if heated above its flash point.
Extinguishing Media:
- Use dry chemical, CO₂, or alcohol-resistant foam.
- Water spray may be used to cool exposed containers.
Hazardous Combustion Products:
- May produce carbon monoxide and carbon dioxide during combustion.
Firefighter Protection:
- Wear full protective clothing and self-contained breathing apparatus (SCBA).
- Keep unnecessary personnel away from the fire area.
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