Lidocaine HCL BP

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Lidocaine HCL BP is a white crystalline powder or granules that are highly soluble in water. It is a local anesthetic and antiarrhythmic agent widely used in medical and dental fields. Lidocaine HCL BP acts by blocking nerve signal transmission, providing rapid and effective numbing of targeted areas. It conforms to British Pharmacopoeia (BP) standards, ensuring pharmaceutical-grade purity and consistency. It is commonly formulated into injections, topical gels, creams, and patches for pain relief and arrhythmia treatment.

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Category: Active Pharmaceutical Ingredients (APIs) Tags: Lidocaine HCL BP, Lidocaine Hydrochloride, Local Anesthetic, Numbing Agent, Pharmaceutical Ingredients

Description

Table of Contents

Lidocaine HCL BP

Primary Uses

Medical and Dental Anesthesia

Local Anesthetic: Used for numbing skin, mucous membranes, and deeper tissues during minor surgical procedures, dental work, and diagnostic tests.
Regional Anesthesia: Employed in nerve blocks, epidurals, and spinal anesthesia for surgeries and pain management.
Topical Anesthesia: Applied in creams, gels, or sprays for superficial pain relief such as sunburn, insect bites, and minor skin irritations.

Cardiology

Antiarrhythmic Agent: Administered intravenously to treat ventricular arrhythmias, including ventricular tachycardia and ventricular fibrillation during acute cardiac events.

Pharmaceutical Formulations

Component in compounded topical analgesics and patches designed for localized pain relief.
Used in combination with other agents to enhance efficacy in multi-ingredient preparations.

Secondary Uses

Veterinary Medicine

Used as a local anesthetic in animals for minor surgical and dental procedures.

Cosmetic Procedures

Utilized to reduce pain during cosmetic interventions such as laser treatments, tattooing, and dermal filler injections.

Research Applications

Used experimentally to study nerve function and local anesthetic pharmacodynamics.

KEY PRODUCT FEATURES

1. Basic Identification Attributes

Chemical Name (IUPAC): 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide hydrochloride
Common/Trade Name: Lidocaine HCL BP; Lidocaine Hydrochloride
CAS Number: 73-78-9
HS Code: 2941.00.00
Synonyms: Lignocaine Hydrochloride; Xylocaine Hydrochloride; Lidocaine HCl

2. Physical & Chemical Properties

Physical State: Crystalline powder
Color & Odor: White to off-white; odorless to faint aromatic odor
Solubility: Freely soluble in water; slightly soluble in alcohol and chloroform
Melting Point: 68–72 °C

3. Safety & Hazard Attributes

GHS Classification: Harmful if swallowed; causes skin and eye irritation; may cause respiratory irritation
Toxicity: Moderate toxicity; overdose can cause CNS and cardiovascular effects
Exposure Limits: No specific occupational limits, but handle with care

4. Storage & Handling Attributes

Storage Conditions: Store in a cool, dry place, protected from light and moisture
Container Type: Sealed pharmaceutical-grade containers
Shelf Life: Typically 2–3 years under proper storage
Handling Precautions: Avoid inhalation and direct contact; use protective equipment

5. Regulatory & Compliance Attributes

Complies with British Pharmacopoeia (BP) standards
Approved for human medical use in many countries
Labeling must comply with pharmaceutical regulatory guidelines

6. Environmental & Health Impact

Biodegradability: Not readily biodegradable
Ecotoxicity: Avoid environmental release; potentially harmful to aquatic life
Bioaccumulation: Not significant
Carcinogenicity/Mutagenicity: Not classified as carcinogenic

SAFETY HANDLING PRECAUTIONS

Safety Handling Precautions

PPE Required: Gloves, safety goggles, and lab coat recommended
Handling Guidelines: Use in well-ventilated areas; avoid dust and inhalation
Storage Measures: Keep containers tightly closed and away from incompatible substances

First Aid Measures

Inhalation: Move to fresh air; seek medical attention if symptoms develop
Skin Contact: Wash with soap and water; seek medical advice if irritation occurs
Eye Contact: Rinse thoroughly with water for at least 15 minutes; seek medical help if irritation persists
Ingestion: Do not induce vomiting; seek immediate medical attention

Firefighting Measures

Fire Hazards: Combustible; emits toxic fumes upon burning
Extinguishing Media: Use water spray, foam, dry chemical, or carbon dioxide
Special Precautions: Wear full protective gear and self-contained breathing apparatus if involved in fire
Hazardous Combustion Products: Carbon monoxide, nitrogen oxides, and other toxic gases