Preservatives(food)
Flavor Enhancers
Acidulants
Sweeteners
Antioxidants
Colorants(food)
Nutraceutical Ingredients (food)
Nutrient Supplements
Emulsifiers
Collectors
Dust Suppressants
Explosives and Blasting Agents
Flocculants and Coagulants
Frothers
Leaching Agents
pH Modifiers
Precious Metal Extraction Agents
Antioxidants(plastic)
Colorants (Pigments, Dyes)
Fillers and Reinforcements
Flame Retardants
Monomers
Plasticizers
Polymerization Initiators
Stabilizers (UV, Heat)
Antifoaming Agents
Chelating Agents
Coagulants and Flocculants
Corrosion Inhibitors
Disinfectants and Biocides
Oxidizing Agents
pH Adjusters
Scale Inhibitors( water)
Antioxidants(cosmetic)
Emollients
Fragrances and Essential Oils
Humectants
Preservatives
Surfactants(cosmetic)
Thickeners
UV Filters
Fertilizers
Soil Conditioners
Plant Growth Regulators
Animal Feed Additives
Biostimulants
Pesticides (Herbicides, Insecticides, Fungicides)
Active Pharmaceutical Ingredients (APIs)
Excipients
Solvents(pharmaceutical)
Antibiotics
Antiseptics and Disinfectants
Vaccine Adjuvants
Nutraceutical Ingredients (pharmaceutical)
Analgesics & Antipyretics
Analytical Reagents
Solvents(lab)
Chromatography Chemicals
Spectroscopy Reagents
microbiology-and-cell-culture-reagents
Molecular Biology Reagents
Biochemical Reagents
Inorganic and Organic Standards
Laboratory Safety Chemicals
Specialty Laboratory Chemicals(Special Laboratory Equipment)
Demulsifiers
Hydraulic Fracturing Fluids
Scale Inhibitors(oil)
Surfactants(oil)
Drilling Fluids
Dyes and Pigments
Bleaching Agents
Softening Agents
Finishing Agents
Antistatic Agents
Admixtures
Waterproofing Agents
Sealants and Adhesives
Curing Compounds
Concrete Repair Chemicals
Anti-Corrosion Coatings
Surfactants(cleaning)
Builders
Enzymes
Solvents (Cleaning)
Fragrances
Electronic Chemicals
Catalysts
Lubricants
Photographic Chemicals
Refrigerants
Automotive chemicals
Pyrotechnic Chemicals
Biodegradable Surfactants
Bio-based Solvents
Renewable Polymers
Carbon Capture Chemicals
Wastewater Treatment Chemicals
Pigments
Solvents(paint)
Specialty Coatings
Binders/Resins
Additives
Driers
Anti-Corrosion Agents
Functional Coatings
Application-Specific Coatings
Leavening Agents
Dough Conditioners
Flour Treatments
Fat Replacers
Decoratives
Preservatives(baking)
Plasticizers & Softeners
Reinforcing Agents
Adhesion Promoters
Vulcanizing Agents
Antidegradants
Blowing Agents
Fillers & Extenders
Accelerators & Retarders
Chlorpheniramine Maleate
Chlorpheniramine Maleate is a first-generation alkylamine antihistamine used primarily to relieve allergy symptoms by blocking H1 histamine receptors. It appears as a white or off-white crystalline powder, freely soluble in water and alcohol. Known for rapid onset and moderate duration of action, it’s widely formulated in pharmaceuticals. It also exhibits mild anticholinergic and sedative effects.
Chlorpheniramine Maleate
Primary Uses
- Pharmaceuticals
- Active ingredient in oral tablets, capsules, and syrups for treatment of:
- Allergic rhinitis (hay fever)
- Urticaria (hives)
- Allergic conjunctivitis
- Anaphylaxis adjunct therapy
- Common cold symptom relief (sneezing, runny nose)
- Used in combination cold, flu, and allergy medications with decongestants, analgesics, and cough suppressants.
- Injectable forms used for rapid allergy symptom relief in emergency or clinical settings.
- Veterinary Medicine
- Treatment of pruritus and allergic reactions in animals including dogs and cats.
- Pharmacology & Toxicology Research
- Widely used in lab research to study histamine H1 receptor antagonism and allergy mechanisms.
Secondary Uses
- Cosmetics & Topical Preparations
- Incorporated in anti-itch creams, lotions, or gels for localized relief of itching and allergic skin reactions (limited use due to systemic absorption concerns).
- Over-the-Counter (OTC) Products
- Included in OTC antihistamine formulations targeting mild allergy symptoms and seasonal hay fever relief.
- Formulation Studies
- Used by pharmaceutical companies in drug formulation development for evaluating bioavailability, stability, and efficacy of antihistamines.
- Analytical Reference Standard
- Employed in quality control laboratories as a reference standard to verify purity and potency of antihistamine drugs.
1. Basic Identification Attributes
- Chemical Name (IUPAC): 3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-2-yl-propan-1-amine maleate
- Common/Trade Name: Chlorpheniramine Maleate
- CAS Number: 132-22-9
- HS Code: 2933.69.90
- Molecular Formula: C16H19ClN2 · C4H4O4
- Synonyms: CPM, Chlorphenamine Maleate
2. Physical & Chemical Properties
- Physical State: White or off-white crystalline powder
- Melting Point: 125–130°C
- Solubility: Freely soluble in water and ethanol; slightly soluble in chloroform and ether
- Stability: Stable under normal conditions; sensitive to light and moisture
3. Safety & Hazard Attributes
- Hazard Class (GHS): Harmful if swallowed; may cause drowsiness or dizziness
- NFPA Ratings: Health 2, Flammability 1, Reactivity 0
- Exposure Limits: No specific limits; dust exposure to be minimized
- Toxicity: Moderate toxicity; overdose can cause anticholinergic effects and CNS depression
4. Storage & Handling Attributes
- Store in cool, dry, dark place; use airtight containers
- Shelf life: 3–5 years
- Use PPE to avoid inhalation and skin contact
5. Regulatory & Compliance Attributes
- Included in USP, BP, EP
- FDA approved as antihistamine active pharmaceutical ingredient
- Registered under REACH and other international regulations
6. Environmental & Health Impact
- Low ecotoxicity; biodegradable; low bioaccumulation potential
- Not classified as carcinogenic or mutagenic
Safety Handling Precautions
- Wear gloves, dust masks, goggles
- Avoid inhalation, skin and eye contact
- Use in well-ventilated areas
First Aid Measures
- Inhalation: Fresh air, medical attention if symptoms persist
- Skin: Wash with soap and water, seek care if irritated
- Eyes: Flush with water, seek medical help if needed
- Ingestion: Do not induce vomiting, seek urgent medical attention
Firefighting Measures
- Combustible; use dry chemical, foam, CO₂
- Wear full protective gear
- Avoid inhalation of combustion products (HCl, nitrogen oxides)
Related products
Diclofenac Sodium BP
Diclofenac Sodium is a nonsteroidal anti-inflammatory drug (NSAID) widely used for its potent analgesic, anti-inflammatory, and antipyretic properties. It is the sodium salt form of diclofenac, providing enhanced solubility and rapid absorption. Diclofenac Sodium BP (British Pharmacopoeia standard) ensures pharmaceutical-grade purity and compliance with stringent quality standards. It is commonly formulated in oral tablets, topical gels, injections, and ophthalmic preparations.
Dicyclomine Hydrochloride
Dicyclomine Hydrochloride is an anticholinergic and antispasmodic agent used primarily to relieve smooth muscle spasms in the gastrointestinal tract. It works by blocking muscarinic receptors, thereby reducing muscle contractions and spasms, which helps alleviate symptoms of irritable bowel syndrome (IBS) and other functional bowel disorders. It is commonly available in oral tablets, capsules, and injectable formulations.
Diloxanide Furoate
Diloxanide Furoate is an orally administered antiprotozoal agent used primarily for the treatment of amoebiasis. It is a furan-based derivative that acts as a luminal amoebicide, effectively targeting Entamoeba histolytica cysts and trophozoites within the intestinal lumen. This compound is well-regarded for its efficacy in eradicating asymptomatic cyst carriers and as a follow-up treatment after systemic amoebicidal therapy. Diloxanide Furoate has good oral bioavailability and a favorable safety profile.
Hydrocortisone Base BP 93 Micro
Hydrocortisone Base BP 93 Micro is a highly purified, micronized form of hydrocortisone base compliant with British Pharmacopoeia (BP) standards. It is a white to off-white fine powder designed for enhanced solubility and bioavailability in pharmaceutical formulations. As a corticosteroid hormone analog, it exhibits potent anti-inflammatory, immunosuppressive, and anti-allergic activities. The micronized particle size (~93 microns) facilitates improved dispersion in topical, injectable, and oral dosage forms.
Lidocaine HCL BP
Lidocaine HCL BP is a white crystalline powder or granules that are highly soluble in water. It is a local anesthetic and antiarrhythmic agent widely used in medical and dental fields. Lidocaine HCL BP acts by blocking nerve signal transmission, providing rapid and effective numbing of targeted areas. It conforms to British Pharmacopoeia (BP) standards, ensuring pharmaceutical-grade purity and consistency. It is commonly formulated into injections, topical gels, creams, and patches for pain relief and arrhythmia treatment.
Mepyramine Maleate BP
Mepyramine Maleate BP is an antihistamine drug commonly used to relieve allergic symptoms such as hay fever, urticaria, and other allergic reactions. It works by blocking histamine H1 receptors, reducing allergic responses like itching, swelling, and redness. This compound is a white or off-white crystalline powder, soluble in water and alcohol, widely used in pharmaceutical formulations including tablets, creams, and injectables.
Metronidazole Benzoate BP
Metronidazole Benzoate BP is a benzoate ester derivative of metronidazole, used primarily as an antiprotozoal and antibacterial agent. It is a prodrug that hydrolyzes in the body to release metronidazole, making it more palatable for pediatric and geriatric oral suspensions. It complies with the British Pharmacopoeia (BP) standards for purity and efficacy.
Norfloxacin
Norfloxacin is a synthetic broad-spectrum fluoroquinolone antibiotic used primarily to treat bacterial infections. It works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication, transcription, repair, and recombination, leading to bacterial cell death. Norfloxacin is effective against various Gram-negative and some Gram-positive bacteria and is commonly used in urinary tract infections, prostatitis, and gastroenteritis.
