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Lidocaine HCL BP
Lidocaine HCL BP is a white crystalline powder or granules that are highly soluble in water. It is a local anesthetic and antiarrhythmic agent widely used in medical and dental fields. Lidocaine HCL BP acts by blocking nerve signal transmission, providing rapid and effective numbing of targeted areas. It conforms to British Pharmacopoeia (BP) standards, ensuring pharmaceutical-grade purity and consistency. It is commonly formulated into injections, topical gels, creams, and patches for pain relief and arrhythmia treatment.
Lidocaine HCL BP
Primary UsesÂ
- Medical and Dental Anesthesia
- Local Anesthetic: Used for numbing skin, mucous membranes, and deeper tissues during minor surgical procedures, dental work, and diagnostic tests.
- Regional Anesthesia: Employed in nerve blocks, epidurals, and spinal anesthesia for surgeries and pain management.
- Topical Anesthesia: Applied in creams, gels, or sprays for superficial pain relief such as sunburn, insect bites, and minor skin irritations.
- Cardiology
- Antiarrhythmic Agent: Administered intravenously to treat ventricular arrhythmias, including ventricular tachycardia and ventricular fibrillation during acute cardiac events.
- Pharmaceutical Formulations
- Component in compounded topical analgesics and patches designed for localized pain relief.
- Used in combination with other agents to enhance efficacy in multi-ingredient preparations.
Secondary Uses
- Veterinary Medicine
- Used as a local anesthetic in animals for minor surgical and dental procedures.
- Cosmetic Procedures
- Utilized to reduce pain during cosmetic interventions such as laser treatments, tattooing, and dermal filler injections.
- Research Applications
- Used experimentally to study nerve function and local anesthetic pharmacodynamics.
1. Basic Identification Attributes
- Chemical Name (IUPAC): 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide hydrochloride
- Common/Trade Name: Lidocaine HCL BP; Lidocaine Hydrochloride
- CAS Number: 73-78-9
- HS Code: 2941.00.00
- Synonyms: Lignocaine Hydrochloride; Xylocaine Hydrochloride; Lidocaine HCl
2. Physical & Chemical Properties
- Physical State: Crystalline powder
- Color & Odor: White to off-white; odorless to faint aromatic odor
- Solubility: Freely soluble in water; slightly soluble in alcohol and chloroform
- Melting Point: 68–72 °C
3. Safety & Hazard Attributes
- GHS Classification: Harmful if swallowed; causes skin and eye irritation; may cause respiratory irritation
- Toxicity: Moderate toxicity; overdose can cause CNS and cardiovascular effects
- Exposure Limits: No specific occupational limits, but handle with care
4. Storage & Handling Attributes
- Storage Conditions: Store in a cool, dry place, protected from light and moisture
- Container Type: Sealed pharmaceutical-grade containers
- Shelf Life: Typically 2–3 years under proper storage
- Handling Precautions: Avoid inhalation and direct contact; use protective equipment
5. Regulatory & Compliance Attributes
- Complies with British Pharmacopoeia (BP) standards
- Approved for human medical use in many countries
- Labeling must comply with pharmaceutical regulatory guidelines
6. Environmental & Health Impact
- Biodegradability: Not readily biodegradable
- Ecotoxicity: Avoid environmental release; potentially harmful to aquatic life
- Bioaccumulation: Not significant
- Carcinogenicity/Mutagenicity: Not classified as carcinogenic
Safety Handling Precautions
- PPE Required: Gloves, safety goggles, and lab coat recommended
- Handling Guidelines: Use in well-ventilated areas; avoid dust and inhalation
- Storage Measures: Keep containers tightly closed and away from incompatible substances
First Aid Measures
- Inhalation: Move to fresh air; seek medical attention if symptoms develop
- Skin Contact: Wash with soap and water; seek medical advice if irritation occurs
- Eye Contact: Rinse thoroughly with water for at least 15 minutes; seek medical help if irritation persists
- Ingestion: Do not induce vomiting; seek immediate medical attention
Firefighting Measures
- Fire Hazards: Combustible; emits toxic fumes upon burning
- Extinguishing Media: Use water spray, foam, dry chemical, or carbon dioxide
- Special Precautions: Wear full protective gear and self-contained breathing apparatus if involved in fire
- Hazardous Combustion Products: Carbon monoxide, nitrogen oxides, and other toxic gases
Related products
Diclofenac Sodium BP
Diclofenac Sodium is a nonsteroidal anti-inflammatory drug (NSAID) widely used for its potent analgesic, anti-inflammatory, and antipyretic properties. It is the sodium salt form of diclofenac, providing enhanced solubility and rapid absorption. Diclofenac Sodium BP (British Pharmacopoeia standard) ensures pharmaceutical-grade purity and compliance with stringent quality standards. It is commonly formulated in oral tablets, topical gels, injections, and ophthalmic preparations.
Gentamycin Sulphate
Gentamycin Sulphate is an aminoglycoside antibiotic derived from Micromonospora purpurea and Micromonospora griseorubida. It appears as a white or off-white crystalline powder, highly soluble in water, with a characteristic aminoglycoside odor. Gentamycin Sulphate is widely used in human and veterinary medicine for its broad-spectrum bactericidal activity against aerobic Gram-negative and some Gram-positive bacteria. It works by inhibiting bacterial protein synthesis through binding to the 30S ribosomal subunit, leading to bacterial cell death. Due to its effectiveness against severe infections and multi-drug resistant strains, it is an essential antibiotic in clinical settings.
Guaiphenesin BP
Guaiphenesin BP is a white crystalline powder or granules with a faint characteristic odor, classified as an expectorant used primarily in pharmaceutical formulations to relieve chest congestion. It works by loosening and thinning mucus in the airways, making it easier to cough up and clear from the respiratory tract. It is widely utilized in cough syrups, tablets, and cold remedies. Recognized for its mucolytic and muscle-relaxant properties, Guaiphenesin is included in both prescription and over-the-counter medications worldwide.
Ivermectin BP Vet
Ivermectin BP Vet is a potent, broad-spectrum antiparasitic agent widely used in veterinary medicine. It belongs to the avermectin family and works by disrupting nerve and muscle function in parasites, leading to paralysis and death. Ivermectin is highly effective against a range of internal and external parasites, including gastrointestinal worms, lungworms, mites, lice, and certain ticks. Available in oral, injectable, and topical forms, it is trusted for use in livestock, poultry, and companion animals. Its reliable efficacy, wide safety margin, and ease of administration make it an essential treatment in animal health and parasite control programs.
Mepyramine Maleate BP
Mepyramine Maleate BP is an antihistamine drug commonly used to relieve allergic symptoms such as hay fever, urticaria, and other allergic reactions. It works by blocking histamine H1 receptors, reducing allergic responses like itching, swelling, and redness. This compound is a white or off-white crystalline powder, soluble in water and alcohol, widely used in pharmaceutical formulations including tablets, creams, and injectables.
Methyl Salicylate BP
Methyl Salicylate BP is a clear, colorless to pale yellow oily liquid with a characteristic strong, sweet, and minty odor. It is an organic ester commonly used for its analgesic, anti-inflammatory, and flavoring properties. Methyl Salicylate is widely used in pharmaceutical preparations, topical pain relief products, cosmetics, and as a fragrance ingredient.
Metronidazole Benzoate BP
Metronidazole Benzoate BP is a benzoate ester derivative of metronidazole, used primarily as an antiprotozoal and antibacterial agent. It is a prodrug that hydrolyzes in the body to release metronidazole, making it more palatable for pediatric and geriatric oral suspensions. It complies with the British Pharmacopoeia (BP) standards for purity and efficacy.
Piperazine Citrate BP
Piperazine Citrate BP is a pharmaceutical-grade anthelmintic compound used primarily for the treatment of intestinal worm infections, especially ascariasis (roundworms) and enterobiasis (pinworms). It works by paralyzing the worms, allowing them to be expelled naturally from the body through bowel movements. Piperazine Citrate is included in the British Pharmacopoeia (BP) and is known for its safety, efficacy, and wide use in both human and veterinary medicine.
