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Oxytetracycline HCL BP
Oxytetracycline HCL BP is a broad-spectrum tetracycline antibiotic used in human and veterinary medicine. It inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, thus preventing the growth and multiplication of susceptible bacteria. Oxytetracycline HCL is effective against a wide range of Gram-positive and Gram-negative bacteria, as well as some protozoa. It is commonly employed to treat respiratory, urinary, and skin infections, and is also used extensively in veterinary applications to control infectious diseases in livestock and poultry.
Oxytetracycline HCL BP
Primary UsesÂ
- Human Medicine
- Treatment of respiratory tract infections (bronchitis, pneumonia).
- Management of urinary tract infections (UTIs).
- Treatment of skin and soft tissue infections.
- Therapy for certain sexually transmitted infections such as chlamydia.
- Used in acne treatment due to its anti-inflammatory properties.
- Veterinary Medicine
- Treatment of bacterial infections in livestock (cattle, sheep, goats).
- Control of respiratory diseases in poultry and swine.
- Management of mastitis in dairy animals.
- Used to treat enteric infections and wound infections in animals.
- Agricultural Applications
- Occasionally used in aquaculture to control bacterial infections in fish.
Secondary UsesÂ
- Protozoal Infections
- Effective against certain protozoa such as Rickettsia species and Mycoplasma.
- Periodontal Therapy
- Used adjunctively in treatment of periodontal (gum) disease.
- Topical Formulations
- Incorporated in ointments and creams for localized bacterial infections and skin conditions.
- Research Applications
- Used in microbiological studies as a selective antibiotic.
1. Basic Identification Attributes
- Chemical Name (IUPAC): (4S,4aS,5aR,6S,12aS)-4-(Dimethylamino)-3,5,6,10,11,12a-hexahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride
- Common/Trade Name: Oxytetracycline Hydrochloride
- CAS Number: 2058-46-0
- HS Code: 2941.40.00
- Synonyms: OTC HCL; Terramycin HCL; Oxytet HCL
2. Physical & Chemical Properties
- Physical State: Fine crystalline powder
- Color & Odor: Yellow to orange-yellow; odorless
- Solubility: Freely soluble in water and dilute acids; slightly soluble in alcohol
- Melting Point: 205–207 °C (decomposes)
3. Safety & Hazard Attributes
- GHS Classification: Harmful if swallowed; may cause skin and respiratory irritation
- Toxicity: Low to moderate toxicity; use with caution and according to dosage instructions
- Exposure Limits: Use protective equipment to avoid inhalation and skin contact
4. Storage & Handling Attributes
- Storage Conditions: Store in a cool, dry place, protected from light
- Container Type: Supplied in airtight containers or bottles
- Shelf Life: Typically 2–3 years if stored properly
- Handling Precautions: Avoid dust inhalation and prolonged skin contact; use gloves and mask if necessary
5. Regulatory & Compliance Attributes
- Complies with BP (British Pharmacopoeia), USP, and other pharmacopeial standards
- Registered for human and veterinary pharmaceutical use
- Complies with national and international antibiotic regulations
6. Environmental & Health Impact
- Biodegradability: Moderately biodegradable
- Ecotoxicity: Avoid release into waterways; may be toxic to aquatic organisms
- Bioaccumulation: Not significantly bioaccumulative
- Carcinogenicity/Mutagenicity: No known carcinogenic effects; standard antibiotic precautions apply
Safety Handling Precautions
- PPE Required: Gloves, lab coat, and respiratory protection recommended during handling
- Handling Guidelines: Work in well-ventilated areas; avoid inhaling dust and direct skin or eye contact
- Storage Measures: Keep containers tightly sealed and away from incompatible substances
First Aid Measures
- Inhalation: Move to fresh air; seek medical advice if symptoms develop
- Skin Contact: Wash thoroughly with soap and water; seek medical attention if irritation persists
- Eye Contact: Rinse immediately with plenty of water for 15 minutes; consult a physician if irritation continues
- Ingestion: Do not induce vomiting; seek immediate medical attention
Firefighting Measures
- Fire Hazards: Non-flammable
- Extinguishing Media: Use water spray, foam, dry chemical, or COâ‚‚ extinguishers as appropriate
- Special Precautions: Use standard protective firefighting equipment
- Hazardous Combustion Products: May emit toxic fumes of nitrogen oxides and carbon oxides under fire conditions
Related products
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Diclofenac Sodium BP
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Diloxanide Furoate
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Doxycycline Hyclate BP
Doxycycline Hyclate BP is a broad-spectrum, semisynthetic tetracycline-class antibiotic available as the hemihydrate salt form of doxycycline. It is widely used in pharmaceutical formulations due to its high bioavailability, broad antibacterial activity, and favorable pharmacokinetic profile. The compound exhibits bacteriostatic action by inhibiting protein synthesis in susceptible bacteria, making it effective against a wide range of Gram-positive and Gram-negative organisms as well as atypical pathogens. It is typically supplied as a fine, white to off-white crystalline powder soluble in water and suitable for oral and parenteral dosage forms.
Gentamycin Sulphate
Gentamycin Sulphate is an aminoglycoside antibiotic derived from Micromonospora purpurea and Micromonospora griseorubida. It appears as a white or off-white crystalline powder, highly soluble in water, with a characteristic aminoglycoside odor. Gentamycin Sulphate is widely used in human and veterinary medicine for its broad-spectrum bactericidal activity against aerobic Gram-negative and some Gram-positive bacteria. It works by inhibiting bacterial protein synthesis through binding to the 30S ribosomal subunit, leading to bacterial cell death. Due to its effectiveness against severe infections and multi-drug resistant strains, it is an essential antibiotic in clinical settings.
Guaiphenesin BP
Guaiphenesin BP is a white crystalline powder or granules with a faint characteristic odor, classified as an expectorant used primarily in pharmaceutical formulations to relieve chest congestion. It works by loosening and thinning mucus in the airways, making it easier to cough up and clear from the respiratory tract. It is widely utilized in cough syrups, tablets, and cold remedies. Recognized for its mucolytic and muscle-relaxant properties, Guaiphenesin is included in both prescription and over-the-counter medications worldwide.
Hydrocortisone Base BP 93 Micro
Hydrocortisone Base BP 93 Micro is a highly purified, micronized form of hydrocortisone base compliant with British Pharmacopoeia (BP) standards. It is a white to off-white fine powder designed for enhanced solubility and bioavailability in pharmaceutical formulations. As a corticosteroid hormone analog, it exhibits potent anti-inflammatory, immunosuppressive, and anti-allergic activities. The micronized particle size (~93 microns) facilitates improved dispersion in topical, injectable, and oral dosage forms.
Ivermectin BP Vet
Ivermectin BP Vet is a potent, broad-spectrum antiparasitic agent widely used in veterinary medicine. It belongs to the avermectin family and works by disrupting nerve and muscle function in parasites, leading to paralysis and death. Ivermectin is highly effective against a range of internal and external parasites, including gastrointestinal worms, lungworms, mites, lice, and certain ticks. Available in oral, injectable, and topical forms, it is trusted for use in livestock, poultry, and companion animals. Its reliable efficacy, wide safety margin, and ease of administration make it an essential treatment in animal health and parasite control programs.
