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Polysorbates
Polysorbates are a class of nonionic surfactants derived from sorbitol and fatty acids, commonly used as emulsifiers, solubilizers, and dispersing agents in a wide range of industries. They improve the mixing of oil and water phases, stabilize emulsions, and enhance the texture and consistency of formulations. Polysorbates are widely used in pharmaceuticals, cosmetics, food products, and industrial applications due to their biocompatibility, low toxicity, and effectiveness at low concentrations.
Polysorbates
Primary Uses
- Pharmaceutical Industry
- Used as emulsifiers and solubilizing agents in oral, topical, and injectable drug formulations.
- Helps to stabilize suspensions and emulsions.
- Improves bioavailability of poorly soluble drugs.
- Food Industry
- Acts as emulsifiers in baked goods, ice creams, salad dressings, and beverages.
- Enhances texture, shelf life, and consistency of food products.
- Used in fat-based spreads and confectionery to improve mixing and prevent separation.
- Cosmetics and Personal Care
- Emulsifies oils and water in creams, lotions, shampoos, and conditioners.
- Enhances product texture, stability, and skin feel.
- Helps disperse fragrances and active ingredients evenly.
- Industrial Applications
- Used in textile processing, detergents, and paints as emulsifiers and dispersants.
- Facilitates the formulation of emulsions and suspensions in various manufacturing processes.
Secondary Uses
- Agriculture
- Used as adjuvants in pesticide formulations to improve spreading and adhesion.
- Biomedical Research
- Employed as stabilizers in vaccine formulations and cell culture media.
- Lubricants and Coatings
- Improves miscibility and stability in lubricant and coating formulations.
- Improves miscibility and stability in lubricant and coating formulations.
1. Basic Identification Attributes
- Chemical Name (IUPAC): Polyoxyethylene sorbitan esters (varies by fatty acid chain)
- Common/Trade Name: Polysorbate 20, Polysorbate 40, Polysorbate 60, Polysorbate 80 (most common types)
- CAS Number: Varies (e.g., Polysorbate 80: 9005-65-6)
- HS Code: 3402.19.00 (Surface-active agents)
- Synonyms: Tween (common trade name), Polyoxyethylene sorbitan fatty acid esters
2. Physical & Chemical Properties
- Physical State: Viscous liquid or semi-solid
- Color: Pale yellow to amber
- Odor: Mild, characteristic odor
- pH: Typically 6.0–8.0 in aqueous solution
- Solubility: Soluble in water and alcohol; forms stable emulsions
- HLB (Hydrophilic-Lipophilic Balance): Range from 8.6 to 16.7 depending on type (higher HLB = more hydrophilic)
- Density: Approx. 1.05 g/cm³
3. Safety & Hazard Attributes
- GHS Classification: Generally not classified as hazardous
- Toxicity: Low toxicity; considered safe for food and cosmetic use within regulatory limits
- Irritation Potential: Mild skin and eye irritant at high concentrations
- Flammability: Non-flammable
4. Storage & Handling Attributes
- Storage Conditions: Store in a cool, dry place away from direct sunlight and heat
- Container Type: Supplied in plastic drums, bottles, or bulk containers
- Shelf Life: Typically 2–3 years if stored properly
- Handling Precautions: Avoid inhalation of aerosols and prolonged skin contact
5. Regulatory & Compliance Attributes
- Complies with:
- FDA regulations for food-grade emulsifiers
- Cosmetic ingredient safety standards (e.g., EU Cosmetic Regulation)
- USP/NF monographs for pharmaceutical grades
- REACH and other international chemical safety regulations
- FDA regulations for food-grade emulsifiers
6. Environmental & Health Impact
- Biodegradability: Readily biodegradable
- Ecotoxicity: Low environmental impact when used as directed
- Bioaccumulation: Not expected to bioaccumulate
- Carcinogenicity/Mutagenicity: Not classified as hazardous
Safety Handling Precautions
- PPE Required: Gloves and safety goggles recommended during handling of concentrated material
- Handling Guidelines: Use in well-ventilated areas; avoid inhalation of mist or aerosols
- Storage Measures: Keep containers tightly closed; avoid contamination
First Aid Measures
- Inhalation: Move to fresh air if irritation occurs
- Skin Contact: Wash with soap and water; seek medical advice if irritation persists
- Eye Contact: Rinse thoroughly with water for at least 15 minutes; seek medical attention if irritation continues
- Ingestion: Rinse mouth; seek medical advice if discomfort or symptoms develop
Firefighting Measures
- Fire Hazards: Not flammable but can burn under fire conditions
- Extinguishing Media: Water spray, foam, dry chemical, or CO₂
- Special Precautions: Use standard protective equipment
- Hazardous Combustion Products: May produce carbon oxides and other toxic fumes during combustion
Related products
Ceteareth 25 Ginonic
Ceteareth 25 Ginonic CSA 25 is a nonionic surfactant and emulsifier derived from the ethoxylation of cetearyl alcohol, incorporating approximately 20 ethylene oxide units per molecule. It appears as a white to off-white waxy solid or viscous liquid, depending on temperature and formulation. This emulsifier is widely used in cosmetic, pharmaceutical, and industrial formulations for its excellent ability to stabilize oil-in-water emulsions, improve texture, and enhance the sensory properties of finished products. Its high hydrophilic-lipophilic balance (HLB) makes it especially effective in forming stable emulsions and solubilizing lipophilic ingredients in aqueous phases. Ceteareth 20 is valued for its mildness, broad compatibility, and multifunctional performance.
Cocodiethanolamide (CDEA)
Cocodiethanolamide (CDEA) is a viscous, amber to dark brown liquid derived from the reaction of coconut oil fatty acids with diethanolamine. It is a non-ionic surfactant and foam stabilizer commonly used in personal care and cleaning products. CDEA enhances foam quality, viscosity, and skin conditioning properties in formulations. Due to its excellent emulsifying and thickening abilities, it is widely used as a secondary surfactant to boost the performance of primary detergents. It is valued for its biodegradability, mildness, and compatibility with various surfactants and other ingredients in cosmetics and industrial formulations.
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Diethanolamine
Diethanolamine is a colorless to pale yellow, viscous liquid with a mild ammonia-like odor. It is a secondary amine and diol, widely used in various industrial, pharmaceutical, and cosmetic applications. DEA is highly soluble in water and many organic solvents. It acts as an intermediate in the synthesis of surfactants, emulsifiers, corrosion inhibitors, and pharmaceuticals. It is valued for its alkalinity, emulsifying properties, and ability to form stable complexes with fatty acids.
Emulsifying Wax Non ionic
Emulsifying Wax Non ionic is a self-emulsifying, non-ionic wax blend composed primarily of fatty alcohols (typically cetostearyl alcohol or stearyl alcohol) and non-ionic surfactants like polyethylene glycol (PEG) derivatives. It is used to stabilize oil-in-water (O/W) emulsions without relying on ionic charges, making it highly compatible with a wide range of ingredients, including both cationic and anionic components. This wax is commonly found in white, odorless solid flakes or pellets and is dispersible in hot water to form smooth, stable emulsions. It is widely used in cosmetic, pharmaceutical, and industrial applications where gentle emulsification, stability, and broad pH compatibility are needed.
Galsilk 700( polyquartenum 7)
Galsilk 700( polyquartenum 7) is a water-soluble cationic polymer known chemically as Polyquaternium-7. It is widely used as a conditioning agent in personal care and cosmetic formulations, prized for its excellent substantivity to hair and skin, providing softness, smoothness, and antistatic effects. This polymer is typically supplied as a clear to slightly hazy viscous liquid or gel. It is compatible with a broad range of surfactants and ingredients, enhancing the sensory profile of shampoos, conditioners, styling products, and skincare formulations. Galsilk 700 is also valued for its film-forming properties and ability to improve product stability.
Guar Gum
Guar Gum is a natural polysaccharide extracted from the endosperm of the guar bean (Cyamopsis tetragonoloba). It appears as an off-white to cream-colored powder with a neutral odor and bland taste. Guar Gum is a galactomannan composed mainly of mannose and galactose units, known for its excellent water-binding, thickening, and stabilizing properties. It forms highly viscous solutions even at low concentrations, making it a versatile hydrocolloid used widely across food, pharmaceutical, cosmetic, oilfield, and industrial applications.
Myristic Acid
Myristic Acid is a saturated fatty acid with a 14-carbon chain, naturally found in nutmeg, coconut oil, palm kernel oil, and butter fat. It appears as a white crystalline solid with a faint odor. It is widely used in the manufacture of soaps, cosmetics, surfactants, and food additives due to its emollient and cleansing properties. Myristic Acid acts as a key intermediate in the production of esters, detergents, and lubricants.
Turkey Red Oil (Sulphated Castor Oil)
Turkey Red Oil (Sulphated Castor Oil), also known as Sulphated Castor Oil, is a water-soluble derivative of castor oil produced by the sulfonation of castor oil. It appears as a viscous, amber to dark brown liquid with excellent emulsifying, detergent, and wetting properties. Turkey Red Oil is widely used as a natural surfactant and emulsifier in various industrial and personal care applications. It is known for its biodegradability, mildness, and ability to stabilize oil-in-water emulsions. Traditionally used in textile processing as a softener and lubricant, it now finds broad usage in cosmetics, detergents, leather processing, and cleaning products due to its unique functional attributes.
