Preservatives(food)
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Fillers and Reinforcements
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Monomers
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microbiology-and-cell-culture-reagents
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Demulsifiers
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Scale Inhibitors(oil)
Surfactants(oil)
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Polysorbates
Polysorbates are a class of nonionic surfactants derived from sorbitol and fatty acids, commonly used as emulsifiers, solubilizers, and dispersing agents in a wide range of industries. They improve the mixing of oil and water phases, stabilize emulsions, and enhance the texture and consistency of formulations. Polysorbates are widely used in pharmaceuticals, cosmetics, food products, and industrial applications due to their biocompatibility, low toxicity, and effectiveness at low concentrations.
Polysorbates
Primary Uses
- Pharmaceutical Industry
- Used as emulsifiers and solubilizing agents in oral, topical, and injectable drug formulations.
- Helps to stabilize suspensions and emulsions.
- Improves bioavailability of poorly soluble drugs.
- Food Industry
- Acts as emulsifiers in baked goods, ice creams, salad dressings, and beverages.
- Enhances texture, shelf life, and consistency of food products.
- Used in fat-based spreads and confectionery to improve mixing and prevent separation.
- Cosmetics and Personal Care
- Emulsifies oils and water in creams, lotions, shampoos, and conditioners.
- Enhances product texture, stability, and skin feel.
- Helps disperse fragrances and active ingredients evenly.
- Industrial Applications
- Used in textile processing, detergents, and paints as emulsifiers and dispersants.
- Facilitates the formulation of emulsions and suspensions in various manufacturing processes.
Secondary Uses
- Agriculture
- Used as adjuvants in pesticide formulations to improve spreading and adhesion.
- Biomedical Research
- Employed as stabilizers in vaccine formulations and cell culture media.
- Lubricants and Coatings
- Improves miscibility and stability in lubricant and coating formulations.
- Improves miscibility and stability in lubricant and coating formulations.
1. Basic Identification Attributes
- Chemical Name (IUPAC): Polyoxyethylene sorbitan esters (varies by fatty acid chain)
- Common/Trade Name: Polysorbate 20, Polysorbate 40, Polysorbate 60, Polysorbate 80 (most common types)
- CAS Number: Varies (e.g., Polysorbate 80: 9005-65-6)
- HS Code: 3402.19.00 (Surface-active agents)
- Synonyms: Tween (common trade name), Polyoxyethylene sorbitan fatty acid esters
2. Physical & Chemical Properties
- Physical State: Viscous liquid or semi-solid
- Color: Pale yellow to amber
- Odor: Mild, characteristic odor
- pH: Typically 6.0–8.0 in aqueous solution
- Solubility: Soluble in water and alcohol; forms stable emulsions
- HLB (Hydrophilic-Lipophilic Balance): Range from 8.6 to 16.7 depending on type (higher HLB = more hydrophilic)
- Density: Approx. 1.05 g/cm³
3. Safety & Hazard Attributes
- GHS Classification: Generally not classified as hazardous
- Toxicity: Low toxicity; considered safe for food and cosmetic use within regulatory limits
- Irritation Potential: Mild skin and eye irritant at high concentrations
- Flammability: Non-flammable
4. Storage & Handling Attributes
- Storage Conditions: Store in a cool, dry place away from direct sunlight and heat
- Container Type: Supplied in plastic drums, bottles, or bulk containers
- Shelf Life: Typically 2–3 years if stored properly
- Handling Precautions: Avoid inhalation of aerosols and prolonged skin contact
5. Regulatory & Compliance Attributes
- Complies with:
- FDA regulations for food-grade emulsifiers
- Cosmetic ingredient safety standards (e.g., EU Cosmetic Regulation)
- USP/NF monographs for pharmaceutical grades
- REACH and other international chemical safety regulations
- FDA regulations for food-grade emulsifiers
6. Environmental & Health Impact
- Biodegradability: Readily biodegradable
- Ecotoxicity: Low environmental impact when used as directed
- Bioaccumulation: Not expected to bioaccumulate
- Carcinogenicity/Mutagenicity: Not classified as hazardous
Safety Handling Precautions
- PPE Required: Gloves and safety goggles recommended during handling of concentrated material
- Handling Guidelines: Use in well-ventilated areas; avoid inhalation of mist or aerosols
- Storage Measures: Keep containers tightly closed; avoid contamination
First Aid Measures
- Inhalation: Move to fresh air if irritation occurs
- Skin Contact: Wash with soap and water; seek medical advice if irritation persists
- Eye Contact: Rinse thoroughly with water for at least 15 minutes; seek medical attention if irritation continues
- Ingestion: Rinse mouth; seek medical advice if discomfort or symptoms develop
Firefighting Measures
- Fire Hazards: Not flammable but can burn under fire conditions
- Extinguishing Media: Water spray, foam, dry chemical, or CO₂
- Special Precautions: Use standard protective equipment
- Hazardous Combustion Products: May produce carbon oxides and other toxic fumes during combustion
Related products
Carbomer
Carbomer is a high molecular weight, crosslinked polyacrylic acid polymer used primarily as a rheology modifier, thickening agent, and suspension stabilizer. Supplied as a fluffy white powder, it exhibits high viscosity and excellent clarity when neutralized and dispersed in water or alcohol-water systems. Carbomer 940 is widely valued for its ability to form clear gels, control flow properties, and stabilize emulsions. It is commonly used in cosmetics, personal care, pharmaceuticals, and household formulations due to its consistency, compatibility, and efficient thickening performance at low concentrations.
Carboxymethyl Cellulose Food Grade
Carboxymethyl Cellulose Food Grade is a water-soluble cellulose derivative produced by the etherification of cellulose with monochloroacetic acid. It appears as a fine, white to off-white powder with excellent thickening, stabilizing, and water retention properties. Designed specifically for food applications, this grade complies with food safety regulations and is widely used as a texture modifier, stabilizer, and emulsifier in a variety of processed foods. It enhances product consistency, extends shelf life, and improves moisture retention without altering taste or odor. Being non-toxic, biodegradable, and non-caloric, it is considered safe for human consumption and is approved as a food additive in many countries.
Cetomacrogol PEG1000 (Ginonic CSA 20)
Cetomacrogol PEG (Ginonic CSA) is a polyethylene glycol-based nonionic surfactant and emulsifier with an average molecular weight of approximately 1000 Da. It appears as a white to off-white waxy solid or flakes with a neutral odor. This high-quality grade is widely used in cosmetic, pharmaceutical, and personal care formulations due to its excellent emulsifying, solubilizing, and moisturizing properties. Cetomacrogol PEG1000 (Ginonic CSA 20) facilitates stable oil-in-water emulsions, improves product texture and skin feel, and enhances the bioavailability of active ingredients. Its hydrophilic nature and compatibility with a wide range of ingredients make it a versatile additive in creams, lotions, ointments, and topical gels.
Cocamino Propyl Betaine Desmocol
Cocamino Propyl Betaine Desmocol is a mild amphoteric surfactant derived from coconut oil fatty acids and amino acids. It appears as a clear to slightly hazy liquid with a faint coconut-like odor. CAPB is widely used in personal care and household cleaning products for its excellent foaming, cleansing, and conditioning properties. Being a zwitterionic surfactant, it is compatible with anionic, cationic, and nonionic surfactants, enhancing the mildness and stability of formulations. The 30% active solution is easy to handle and incorporate in various cosmetic and detergent products. It functions as a foam booster, viscosity builder, and anti-irritant agent, making it a versatile ingredient in mild formulations.
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Diethanolamine
Diethanolamine is a colorless to pale yellow, viscous liquid with a mild ammonia-like odor. It is a secondary amine and diol, widely used in various industrial, pharmaceutical, and cosmetic applications. DEA is highly soluble in water and many organic solvents. It acts as an intermediate in the synthesis of surfactants, emulsifiers, corrosion inhibitors, and pharmaceuticals. It is valued for its alkalinity, emulsifying properties, and ability to form stable complexes with fatty acids.
Oleic Acid
Oleic Acid is a naturally occurring monounsaturated fatty acid commonly derived from vegetable oils such as olive, sunflower, and canola oils. This oily liquid is widely used in the chemical, pharmaceutical, cosmetic, and food industries due to its excellent emollient, surfactant, and stabilizing properties. Oleic Acid 75% is a key raw material in manufacturing soaps, detergents, lubricants, and personal care products. Its amphiphilic nature makes it an effective emulsifier and penetration enhancer.
Polyglycerol-10-Laurate
Polyglycerol-10-Laurate is a non-ionic, biodegradable surfactant and emulsifier derived from natural lauric acid and polyglycerol (with ten glycerol units). It is known for its excellent emulsifying, dispersing, and solubilizing properties, especially in oil-in-water systems. Commonly used in cosmetics, food, pharmaceuticals, and personal care products, it is valued for being mild, non-toxic, and suitable for sensitive applications, including baby care and oral care.
Turkey Red Oil (Sulphated Castor Oil)
Turkey Red Oil (Sulphated Castor Oil), also known as Sulphated Castor Oil, is a water-soluble derivative of castor oil produced by the sulfonation of castor oil. It appears as a viscous, amber to dark brown liquid with excellent emulsifying, detergent, and wetting properties. Turkey Red Oil is widely used as a natural surfactant and emulsifier in various industrial and personal care applications. It is known for its biodegradability, mildness, and ability to stabilize oil-in-water emulsions. Traditionally used in textile processing as a softener and lubricant, it now finds broad usage in cosmetics, detergents, leather processing, and cleaning products due to its unique functional attributes.
