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Povidone Iodide BP

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Povidone Iodide BP is a water-soluble complex of iodine with the synthetic polymer polyvinylpyrrolidone (PVP). It acts as a broad-spectrum antiseptic effective against bacteria, fungi, viruses, and protozoa. Widely used in medical, pharmaceutical, and veterinary fields, Povidone Iodine provides sustained iodine release, minimizing irritation while offering rapid antimicrobial action. It is essential for wound care, surgical preparation, and infection control.

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Description

Povidone Iodide BP

Primary Uses

  1. Medical and Healthcare
  • Used as a topical antiseptic for skin disinfection before and after surgery.
  • Applied to minor wounds, cuts, and burns to prevent infection.
  • Used in surgical scrubs and hand washes for healthcare personnel.
  • Employed in mouthwashes and throat gargles for oral antisepsis.
  1. Veterinary Medicine
  • Used for wound care and infection prevention in animals.
  • Applied to surgical sites and during animal handling procedures.
  1. Pharmaceuticals
  • Incorporated in antiseptic creams, ointments, and solutions for infection control.

Secondary Uses 

  1. Water Treatment
  • Used in low concentrations for water disinfection in emergency situations.
  1. Laboratory Use
  • Employed as an antimicrobial agent in microbiological and histological preparations.
  1. Cosmetics
  • Occasionally used in antiseptic skincare formulations.
KEY PRODUCT FEATURES

1. Basic Identification Attributes

  • Chemical Name (IUPAC): Povidone-iodine complex
  • Common/Trade Name: Povidone Iodine BP
  • CAS Number: 25655-41-8
  • HS Code: 3004.90
  • Synonyms: PVP-Iodine; Betadine (brand name)

2. Physical & Chemical Properties

  • Physical State: Dark brown solution or ointment
  • Color & Odor: Brown with characteristic iodine odor
  • Solubility: Soluble in water
  • pH: Typically 2.0 – 4.5 (aqueous solutions)
  • Density: ~1.1 g/cm³ (solution)
  • Stability: Stable under normal conditions; sensitive to light

3. Safety & Hazard Attributes

  • GHS Classification: May cause skin and eye irritation; harmful if swallowed
  • Toxicity: Low systemic toxicity when used topically; iodine sensitivity possible
  • Exposure Limits: Avoid prolonged exposure; use gloves and eye protection

4. Storage & Handling Attributes

  • Storage Conditions: Store in tightly closed containers away from light and heat
  • Container Type: Plastic or glass bottles, tubes, or dispensers
  • Shelf Life: Typically 2–3 years if stored properly
  • Handling Precautions: Use gloves; avoid contact with eyes and mucous membranes

5. Regulatory & Compliance Attributes

  • Complies with BP (British Pharmacopoeia) standards
  • Approved for medical and pharmaceutical use worldwide

6. Environmental & Health Impact

  • Biodegradability: Polyvinylpyrrolidone is biodegradable; iodine released degrades to iodide ions
  • Ecotoxicity: Low environmental impact when used as directed
  • Bioaccumulation: Not significant
SAFETY HANDLING PRECAUTIONS

Safety Handling Precautions

  • PPE Required: Gloves and eye protection recommended
  • Handling Guidelines: Avoid direct contact with skin and eyes; handle in well-ventilated areas
  • Storage Measures: Keep container tightly closed and protected from light

First Aid Measures

  • Inhalation: Move to fresh air; seek medical attention if respiratory irritation occurs
  • Skin Contact: Wash thoroughly with water; seek medical advice if irritation develops
  • Eye Contact: Rinse immediately with plenty of water for at least 15 minutes; seek urgent medical attention
  • Ingestion: Rinse mouth; do not induce vomiting; seek medical help promptly

Firefighting Measures

  • Fire Hazards: Non-flammable
  • Extinguishing Media: Use water spray, foam, dry chemical, or CO₂
  • Special Precautions: None specific to povidone iodine
  • Hazardous Combustion Products: May release iodine vapors under fire conditions

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