PVP Iodine

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PVP Iodine is a water-soluble complex of polyvinylpyrrolidone (PVP) and iodine, widely used as a broad-spectrum antiseptic. It delivers controlled iodine release, providing effective antimicrobial action against bacteria, viruses, fungi, and protozoa. This preparation is favored for its ease of application, reduced irritation compared to tinctures, and stability in aqueous solutions. PVP Iodine 10% is commonly used in medical, veterinary, and personal care settings for disinfection and wound treatment.

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Categories: Antiseptics and Disinfectants, Bleaching Agents, CLEANING AND DETERGENT CHEMICALS, LABORATORY EQUIPMENT & APPARATUS, PHARMACEUTICAL CHEMICALS Tags: Disinfectant & Antimicrobial Agent, Iodophor Antiseptic, Povidone-Iodine Solution, PVP-Iodine, Wound Cleaning & Skin Disinfection

Description

Table of Contents

PVP Iodine

Primary Uses

Medical & Healthcare
Used as a topical antiseptic for preoperative skin preparation and wound cleaning.

Applied in treatment and prevention of minor cuts, abrasions, burns, and infections.

Employed in surgical scrubs and hand sanitizers for healthcare professionals.

Dental Care
Used as an oral disinfectant in mouthwashes and gargles to reduce oral microbial load.

Applied in the management of oral mucosal infections and periodontal therapy.

Veterinary Medicine
Used for disinfecting animal skin and wounds.

Employed in surgical preparation and post-operative care in veterinary clinics.

Personal Care & Hygiene
Incorporated in antiseptic creams, ointments, and washes for household first aid.

Used in feminine hygiene products and skin cleansers for infection prevention.

Secondary Uses

Water Treatment
Occasionally used for disinfecting drinking water in emergency or field conditions.

Laboratory & Research
Used as a microbial control agent in microbiology labs and research settings.

Cosmetics
Incorporated in formulations requiring antimicrobial preservation without harsh solvents.

Food Industry
Employed in sanitizing food contact surfaces and equipment in food processing facilities (non-food additive).

PRODUCT KEY FEATURES

Basic Identification Attributes

Chemical Name (IUPAC): Poly(1-vinyl-2-pyrrolidone)-iodine complex
Common/Trade Name: PVP Iodine 10%
CAS Number: 25655-41-8 (PVP), 7553-56-2 (iodine)
HS Code: 3004.90.90
Synonyms: Povidone-iodine 10%; Betadine (brand)

Physical & Chemical Properties

Physical State: Aqueous solution
Color & Odor: Brownish-red; characteristic iodine odor
pH: Approximately 3.5–5.5
Solubility: Soluble in water
Iodine Content: Typically 10% available iodine by weight

Safety & Hazard Attributes

GHS Classification: Eye irritant, skin sensitizer (depending on concentration)
Toxicity: Low systemic toxicity when used topically; avoid ingestion and prolonged skin exposure
Exposure Limits: Use as per recommended medical guidelines

Storage & Handling Attributes

Storage Conditions: Store in a cool, dry place protected from light and heat
Container Type: Supplied in plastic or glass bottles with secure caps
Shelf Life: Typically 2 years if stored properly
Handling Precautions: Avoid contact with eyes and mucous membranes; use gloves when applying to large wounds

Regulatory & Compliance Attributes

Complies with USP, BP, and EP pharmacopoeial standards for antiseptics
Approved by FDA and EMA for topical antiseptic use
Manufactured in GMP-certified pharmaceutical facilities

Environmental & Health Impact

Biodegradability: Biodegradable components; iodine may be toxic to aquatic life in large quantities
Ecotoxicity: Moderate ecotoxicity; avoid disposal into waterways
Bioaccumulation: Not significant

SAFETY HANDLING PRECAUTIONS

PPE Required: Gloves recommended during application; eye protection if splashing possible

Handling Guidelines: Use in well-ventilated areas; avoid ingestion and prolonged skin contact

Storage Measures: Keep containers tightly closed and stored in a dry, cool environment away from direct sunlight

First Aid Measures
Inhalation: Move to fresh air if respiratory irritation occurs

Skin Contact: Wash with soap and water; discontinue use if irritation develops

Eye Contact: Rinse immediately with plenty of water for at least 15 minutes; seek medical attention

Ingestion: Do not induce vomiting; seek immediate medical help

Firefighting Measures
Fire Hazards: Non-flammable aqueous solution

Extinguishing Media: Use water spray, foam, dry chemical, or CO₂ on surrounding fire

Special Precautions: None specific; standard firefighting protective equipment recommended

Hazardous Combustion Products: May release iodine vapors if heated to decomposition