Sodium Methyl Paraben
Sodium Methyl Paraben is the sodium salt of methylparaben, a widely used preservative in cosmetics, pharmaceuticals, and food. It is a white, odorless, crystalline powder that is water-soluble and effective against a broad spectrum of bacteria, molds, and yeasts. As a paraben derivative, it helps prevent microbial contamination and extends shelf life. It is often preferred over methylparaben in formulations where water solubility is required.
Sodium Methyl Paraben
Primary Uses
- Pharmaceuticals
- Used as an antimicrobial preservative in oral and topical medicinal formulations.
- Stabilizes syrups, suspensions, creams, and eye drops by preventing microbial growth.
- Cosmetics & Personal Care
- Added to lotions, creams, shampoos, and deodorants to inhibit bacterial and fungal contamination.
- Ensures product safety and longevity in water-based personal care items.
- Food Industry
- Utilized in beverages, sauces, and processed foods as a preservative to control spoilage.
- Helps extend shelf life by inhibiting yeast and mold growth (where permitted by food regulations).
Secondary Uses
- Veterinary Products
- Used in animal pharmaceuticals and topical veterinary treatments as a preservative.
- Laboratory & Research Chemicals
- Acts as a reference or control preservative in microbiological and pharmaceutical research.
- Textile & Leather Processing
- Occasionally used in water-based treatments where preservation against microbial contamination is needed.
1. Basic Identification Attributes
- Chemical Name (IUPAC): Sodium 4-(methoxycarbonyl)phenolate
- Common/Trade Name: Sodium Methyl Paraben
- CAS Number: 5026-62-0
- HS Code: 2918.23.00
- Synonyms: Methylparaben sodium salt; Sodium methyl 4-hydroxybenzoate
2. Physical & Chemical Properties
- Physical State: Solid (crystalline powder)
- Color & Odor: White, odorless
- Solubility: Highly soluble in water and alcohol
- pH (1% solution): Approx. 9.5–10.5
- Melting Point: ~125–128°C (decomposes)
- Stability: Stable under normal storage conditions
3. Safety & Hazard Attributes
- GHS Classification: Not classified as hazardous under normal conditions
- Toxicity: Low; considered safe at approved concentrations in food and personal care products
- Exposure Limits: Follow GMP and cosmetic/pharmaceutical regulations
- Allergies: Rare cases of skin irritation or allergic response in sensitive individuals
4. Storage & Handling Attributes
- Storage Conditions: Store in a cool, dry place, away from light and moisture
- Container Type: Food-grade or pharmaceutical-grade plastic containers or fiber drums
- Shelf Life: Typically 2–3 years under recommended conditions
- Handling Precautions: Avoid inhalation of dust; use gloves and eye protection when handling in bulk
5. Regulatory & Compliance Attributes
- Complies with relevant pharmacopeial standards (e.g., USP, BP, EP)
- Approved for use by FDA, EFSA, and other regulatory authorities within defined limits
- Listed under international chemical inventories (REACH, TSCA, AICS)
- Subject to concentration limits for use in cosmetics and foods as per regional legislation
- Requires appropriate labeling when used in consumer products
- Manufactured in accordance with cGMP and ISO quality systems
6. Environmental & Health Impact
- Biodegradability: Readily biodegradable in natural environments
- Ecotoxicity: Low environmental impact at permitted usage levels
- Bioaccumulation: Negligible due to rapid breakdown and low persistence
Safety Handling Precautions
- PPE Required: Gloves, goggles, lab coat or protective clothing
- Handling Guidelines: Avoid contact with eyes and inhalation of powder
- Storage Measures: Keep tightly sealed in original containers; avoid exposure to heat or humidity
First Aid Measures
- Inhalation: Move to fresh air; seek medical attention if respiratory symptoms develop
- Skin Contact: Wash with soap and water; discontinue use if irritation occurs
- Eye Contact: Rinse with plenty of water; seek medical attention if irritation persists
- Ingestion: Rinse mouth with water; consult a healthcare provider if necessary
Firefighting Measures
- Fire Hazards: Non-flammable but may decompose at high temperatures
- Extinguishing Media: Use water spray, dry chemical, CO₂, or foam
- Special Precautions: Use self-contained breathing apparatus in enclosed areas
- Hazardous Combustion Products: May emit carbon oxides on combustion
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