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Sulphamethoxazole BP micronised
Sulphamethoxazole BP Micronised is a fine, micronized form of sulphamethoxazole, a synthetic sulfonamide antibiotic used extensively in human and veterinary medicine. Micronization improves its dissolution rate and bioavailability, enhancing efficacy in oral and injectable formulations. This British Pharmacopoeia (BP) grade product ensures high purity and consistent particle size, making it ideal for pharmaceutical manufacturing.
Sulphamethoxazole BP micronised
Primary Uses
- Human Medicine
- Antibacterial Agent: Used in treatment of urinary tract infections, respiratory infections, gastrointestinal infections, and Pneumocystis pneumonia, often in combination with trimethoprim (co-trimoxazole).
- Improved Formulations: Micronized powder enhances solubility and absorption in tablets, suspensions, and injectables.
- Veterinary Medicine
- Antimicrobial Agent: Used for bacterial infections in livestock and companion animals, including respiratory and urinary tract infections.
- Medicated Feeds and Injectables: Ideal for veterinary formulations requiring enhanced bioavailability.
Secondary Uses
- Pharmaceutical Research & Development
- Formulation Development: Used to improve dissolution rates and bioavailability studies.
- Microbiological Testing: Employed in bacterial sensitivity assays and antibiotic resistance research.
- Public Health
- Prophylaxis and Treatment: Used in immunocompromised patients to prevent opportunistic infections.
1. Basic Identification Attributes
- Chemical Name (IUPAC): 4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide
- Common/Trade Name: Sulphamethoxazole BP Micronised
- CAS Number: 723-46-6
- HS Code: 2941.20.00
- Synonyms: Sulfamethoxazole micronized, SMX micronized
2. Physical & Chemical Properties
- Physical State: Fine, white to off-white crystalline powder
- Color & Odor: White; faint sulfur-like odor
- Particle Size: Micronized for enhanced dissolution (typically <10 microns)
- Melting Point: 169–172 °C
- Solubility: Slightly soluble in water; soluble in alkaline solutions and ethanol
- Density: Approx. 1.4 g/cm³
3. Safety & Hazard Attributes
- GHS Classification: May cause allergic skin reactions and hypersensitivity
- Toxicity: Moderate toxicity; avoid prolonged exposure
- Exposure Limits: No specific occupational limits; observe good industrial hygiene
4. Storage & Handling Attributes
- Storage Conditions: Store in a cool, dry, well-ventilated area away from light and moisture
- Container Type: Sealed airtight containers or drums
- Shelf Life: 24 months under recommended conditions
- Handling Precautions: Minimize dust generation; use gloves and dust masks
5. Regulatory & Compliance Attributes
- Complies with British Pharmacopoeia (BP) standards
- Manufactured under Good Manufacturing Practices (GMP)
- Suitable for human and veterinary pharmaceutical use
6. Environmental & Health Impact
- Biodegradability: Limited; degrades slowly under aerobic conditions
- Ecotoxicity: Potentially harmful to aquatic life; avoid environmental discharge
- Bioaccumulation: Not significant
Safety Handling Precautions
- PPE Required: Gloves, protective clothing, and dust masks recommended
- Handling Guidelines: Use adequate ventilation to control dust exposure
- Storage Measures: Keep containers tightly sealed and dry
First Aid Measures
- Inhalation: Remove to fresh air; seek medical attention if symptoms develop
- Skin Contact: Wash thoroughly with soap and water
- Eye Contact: Flush with water for 15 minutes; seek medical help if irritation continues
- Ingestion: Rinse mouth; obtain medical advice if necessary
Firefighting Measures
- Fire Hazards: Combustible solid
- Extinguishing Media: Water spray, foam, dry chemical, or CO₂ extinguishers
- Hazardous Combustion Products: Carbon oxides, nitrogen oxides, sulfur oxides
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Doxycycline Hyclate BP
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Gentamycin Sulphate
Gentamycin Sulphate is an aminoglycoside antibiotic derived from Micromonospora purpurea and Micromonospora griseorubida. It appears as a white or off-white crystalline powder, highly soluble in water, with a characteristic aminoglycoside odor. Gentamycin Sulphate is widely used in human and veterinary medicine for its broad-spectrum bactericidal activity against aerobic Gram-negative and some Gram-positive bacteria. It works by inhibiting bacterial protein synthesis through binding to the 30S ribosomal subunit, leading to bacterial cell death. Due to its effectiveness against severe infections and multi-drug resistant strains, it is an essential antibiotic in clinical settings.
Ivermectin BP Vet
Ivermectin BP Vet is a potent, broad-spectrum antiparasitic agent widely used in veterinary medicine. It belongs to the avermectin family and works by disrupting nerve and muscle function in parasites, leading to paralysis and death. Ivermectin is highly effective against a range of internal and external parasites, including gastrointestinal worms, lungworms, mites, lice, and certain ticks. Available in oral, injectable, and topical forms, it is trusted for use in livestock, poultry, and companion animals. Its reliable efficacy, wide safety margin, and ease of administration make it an essential treatment in animal health and parasite control programs.
Levamisole Hcl BP2000
Levamisole Hcl BP2000 is a white to off-white crystalline powder, soluble in water, with anthelmintic and immunomodulatory properties. It is primarily used as a veterinary antiparasitic agent effective against gastrointestinal nematodes in livestock. Levamisole HCL BP2000 conforms to British Pharmacopoeia standards, ensuring high purity and quality for pharmaceutical and veterinary formulations. Beyond veterinary uses, it is also researched for immunostimulant properties in medical applications.
Mepyramine Maleate BP
Mepyramine Maleate BP is an antihistamine drug commonly used to relieve allergic symptoms such as hay fever, urticaria, and other allergic reactions. It works by blocking histamine H1 receptors, reducing allergic responses like itching, swelling, and redness. This compound is a white or off-white crystalline powder, soluble in water and alcohol, widely used in pharmaceutical formulations including tablets, creams, and injectables.
Metronidazole Benzoate BP
Metronidazole Benzoate BP is a benzoate ester derivative of metronidazole, used primarily as an antiprotozoal and antibacterial agent. It is a prodrug that hydrolyzes in the body to release metronidazole, making it more palatable for pediatric and geriatric oral suspensions. It complies with the British Pharmacopoeia (BP) standards for purity and efficacy.
Miconazole Nitrate BP
Miconazole Nitrate BP is a high-purity, pharmaceutical-grade antifungal agent conforming to British Pharmacopoeia (BP) specifications. It is widely used in the formulation of topical and oral pharmaceutical products for the treatment of fungal infections caused by dermatophytes and yeasts, including Candida species. Miconazole Nitrate functions by inhibiting the biosynthesis of ergosterol, a vital component of fungal cell membranes, leading to cell death.
This white to off-white crystalline powder is highly effective and exhibits broad-spectrum antifungal and some antibacterial activity. It is commonly utilized in creams, ointments, powders, and gel formulations.
